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Neuroscience

D-Index
56
Citations
15287
World Ranking
4459
National Ranking
2019

Research.com Recognitions

  • 1998 - Fellow of Alfred P. Sloan Foundation

Overview

Alfredo Kirkwood is affiliated with Johns Hopkins University in the United States and has contributed extensively to the field of neuroscience, focusing particularly on cellular and molecular neuroscience as well as cognitive neuroscience. Their research spans several subfields, with a primary emphasis on neural dynamics, brain function, and molecular biology.

Their work has been published in various scientific venues, notably including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 11 publications
  • Frontiers in Synaptic Neuroscience, 4 publications
  • iScience, 3 publications
  • Nature Communications, 2 publications
  • Proceedings of the National Academy of Sciences, 2 publications

Alfredo Kirkwood's recent papers demonstrate a focus on synaptic plasticity, neural signaling mechanisms, and cognitive functions. Some of their latest publications include:

  • "SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity," 2024, Science
  • "Norepinephrine potentiates and serotonin depresses visual cortical responses by transforming eligibility traces," 2022, Nature Communications
  • "NMDA Receptor-Arc Signaling Is Required for Memory Updating and Is Disrupted in Alzheimer's Disease," 2023, Biological Psychiatry
  • "All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity," 2021, Proceedings of the National Academy of Sciences
  • "Mouse models of SYNGAP1-related intellectual disability," 2023, Proceedings of the National Academy of Sciences

Their collaborative network includes frequent coauthors such as Daniel Severín, Michelle Bridi, Su Z. Hong, Cristian Moreno, and Hey-Kyoung Lee.

In terms of research topics, Alfredo Kirkwood covers a diverse range, including:

  • Neuroscience and Neuropharmacology Research
  • Neural dynamics and brain function
  • Photoreceptor and optogenetics research
  • Memory and Neural Mechanisms
  • Genetics and Neurodevelopmental Disorders
  • Retinal Development and Disorders
  • Cellular transport and secretion

Their published books include a title from Frontiers Media:

  • "The Synaptic Basis of Neuropathology," 2023

Alfredo Kirkwood has received recognition as a Fellow of the Alfred P. Sloan Foundation, awarded in 1998.

Best Publications

  • BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

    Z. Josh Huang;Alfredo Kirkwood;Tommaso Pizzorusso;Vittorio Porciatti

  • Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration

    Carlos A. Saura;Se Young Choi;Vassilios Beglopoulos;Seema Malkani

  • Experience-dependent modification of synaptic plasticity in visual cortex.

    Alfredo Kirkwood;Marika G. Rioult;Mark F. Bear

  • Aberrant light directly impairs mood and learning through melanopsin-expressing neurons

    Tara A. Legates;Cara M. Altimus;Hui Wang;Hey Kyoung Lee

  • Common forms of synaptic plasticity in the hippocampus and neocortex in vitro.

    Alfredo Kirkwood;Serena M. Dudek;Joel T. Gold;Carlos D. Aizenman

  • Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience

    Alfredo Kirkwood;Hey Kyoung Lee;Mark F. Bear

  • α-CaMKII-dependent plasticity in the cortex is required for permanent memory

    Paul W. Frankland;Cara O'Brien;Masuo Ohno;Alfredo Kirkwood

  • Hebbian synapses in visual cortex

    Alfredo Kirkwood;Mark F. Bear

  • Seminars in Cell & Developmental Biology

    Hey-Kyoung Lee;Alfredo Kirkwood

  • Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity.

    Geun Hee Seol;Jokubas Ziburkus;Jokubas Ziburkus;Shi Yong Huang;Lihua Song

  • Light Affects Mood and Learning through Distinct Retina-Brain Pathways

    Diego Carlos Fernandez;P. Michelle Fogerson;Lorenzo Lazzerini Ospri;Michael B. Thomsen

  • Modulation of Long-Term Synaptic Depression in Visual Cortex by Acetylcholine and Norepinephrine

    Alfredo Kirkwood;Carlos Rozas;John Kirkwood;Fernanda Perez

  • Dark Rearing Alters the Development of GABAergic Transmission in Visual Cortex

    Bernardo Morales;Se Young Choi;Alfredo Kirkwood

  • Homosynaptic long-term depression in the visual cortex.

    Alfredo Kirkwood;Mark F. Bear

  • Timing is not Everything: Neuromodulation Opens the STDP Gate

    Verena Pawlak;Jeffery R Wickens;Alfredo Kirkwood;Jason N D Kerr

  • Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice

    Mansuo L. Hayashi;Se Young Choi;B. S. Shankaranarayana Rao;Hae Yoon Jung

  • APP Processing and Synaptic Plasticity in Presenilin-1 Conditional Knockout Mice

    Huakui Yu;Carlos A. Saura;Se Young Choi;Linus D. Sun

  • Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF

    Laura Gianfranceschi;Rosita Siciliano;Jennifer Walls;Bernardo Morales

  • Cross-modal regulation of synaptic AMPA receptors in primary sensory cortices by visual experience

    Anubhuthi Goel;Bin Jiang;Linda W Xu;Lihua Song

  • Distinct Eligibility Traces for LTP and LTD in Cortical Synapses

    Kaiwen He;Marco Huertas;Su Z. Hong;Xiao Xiu Tie

  • Neocortical long-term potentiation.

    Mark F. Bear;Alfredo Kirkwood

Frequent Co-Authors

Hey Kyoung Lee
Hey Kyoung Lee Johns Hopkins University
Michela Gallagher
Michela Gallagher Johns Hopkins University
Samer Hattar
Samer Hattar National Institutes of Health
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Sumantra Chattarji
Sumantra Chattarji National Centre for Biological Sciences
Z. Josh Huang
Z. Josh Huang Cold Spring Harbor Laboratory
Stefan Mihalas
Stefan Mihalas Allen Institute for Brain Science
Karen Duff
Karen Duff University College London

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