World's Best Scientists 2026 revealed!
Mark F. Bear

Mark F. Bear

D-Index & Metrics

Neuroscience

D-Index
112
Citations
66992
World Ranking
499
National Ranking
294

Research.com Recognitions

  • 2004 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Mark F. Bear is affiliated with MIT in the United States and is active in research related to neuroscience and related fields. Their work spans multiple areas, including neuroscience, biochemistry, genetics, molecular biology, and medicine, with a particular focus on subfields such as cellular and molecular neuroscience, cognitive neuroscience, molecular biology, ophthalmology, and genetics.

Their main research topics include:

  • Neuroscience and neuropharmacology research
  • Genetics and neurodevelopmental disorders
  • Neural dynamics and brain function
  • Retinal development and disorders
  • Glaucoma and retinal disorders
  • Photoreceptor and optogenetics research
  • Memory and neural mechanisms

Mark F. Bear has contributed to several recent papers, including:

  • Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain (2021, Cell Reports)
  • Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator (2020, Neuron)
  • Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics (2020, Cell)
  • Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice (2020, Molecular Psychiatry)
  • Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome (2020, Science Translational Medicine)

The scientist frequently publishes in outlets such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Journal of Neuroscience, Journal of Neuro-Ophthalmology, and Neuron. The volume of publications in these venues includes 13 in bioRxiv, 3 in Cell Reports, 3 in Journal of Neuroscience, 2 in Journal of Neuro-Ophthalmology, and 1 in Neuron.

Mark F. Bear has collaborated repeatedly with several researchers, including:

  • Samuel F. Cooke
  • Peter S.B. Finnie
  • Eric D. Gaier
  • Arnold J. Heynen
  • Aurore Thomazeau

The scientist has been recognized as a fellow by multiple organizations, including the American Academy of Arts and Sciences since 2004, the American Association for the Advancement of Science (AAAS) since 2003, and the Alfred P. Sloan Foundation starting in 1987.

Best Publications

  • LTP and LTD: an embarrassment of riches.

    Robert C. Malenka;Mark F. Bear

  • Neuroscience: Exploring the Brain

    Mark F. Bear;Barry W. Connors;Michael A. Paradiso

  • Learning Induces Long-Term Potentiation in the Hippocampus

    Jonathan R. Whitlock;Jonathan R. Whitlock;Arnold J. Heynen;Marshall G. Shuler;Mark F. Bear

  • Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

    Serena M. Dudek;Mark F. Bear

  • Metaplasticity: the plasticity of synaptic plasticity.

    Wickliffe C. Abraham;Mark F. Bear

  • The mGluR theory of fragile X mental retardation

    Mark F Bear;Kimberly M Huber;Stephen T Warren

  • Synaptic plasticity: LTP and LTD

    Mark F. Bear;Robert C. Malenka

  • Altered synaptic plasticity in a mouse model of fragile X mental retardation

    Kimberly M. Huber;Kimberly M. Huber;Sean M. Gallagher;Stephen T. Warren;Mark F. Bear

  • BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

    Z. Josh Huang;Alfredo Kirkwood;Tommaso Pizzorusso;Vittorio Porciatti

  • Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity.

    Hey Kyoung Lee;Michaela Barbarosie;Kimihiko Kameyama;Mark F. Bear

  • Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression.

    Kimberly M. Huber;Matthew S. Kayser;Mark F. Bear

  • Correction of fragile X syndrome in mice.

    Gül Dölen;Emily Osterweil;B.S. Shankaranarayana Rao;Gordon B. Smith

  • Modulation of visual cortical plasticity by acetylcholine and noradrenaline

    Mark F. Bear;Mark F. Bear;Wolf Singer

  • Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex

    Andreas Kleinschmidt;Mark F. Bear;Wolf Singer

  • NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus

    Hey Kyoung Lee;Kimihiko Kameyama;Richard L. Huganir;Mark F. Bear

  • Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

    Huda Y. Zoghbi;Mark F. Bear

  • Experience-dependent modification of synaptic plasticity in visual cortex.

    Alfredo Kirkwood;Marika G. Rioult;Mark F. Bear

  • Long-Term Depression in Hippocampus

    Mark F. Bear;Wickliffe C. Abraham

  • A unified model of NMDA receptor-dependent bidirectional synaptic plasticity

    Harel Z. Shouval;Mark F. Bear;Leon N Cooper

  • Reward Timing in the Primary Visual Cortex

    Marshall G. Shuler;Mark F. Bear

  • Learning and memory

    Daniel L. Alkon;David G. Amaral;Mark F. Bear;Joel Black

Frequent Co-Authors

Kimberly M. Huber
Kimberly M. Huber The University of Texas Southwestern Medical Center
Benjamin D. Philpot
Benjamin D. Philpot University of North Carolina at Chapel Hill
Alfredo Kirkwood
Alfredo Kirkwood Johns Hopkins University
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Stephen T. Warren
Stephen T. Warren Emory University
Peter C. Kind
Peter C. Kind University of Edinburgh
Sumantra Chattarji
Sumantra Chattarji National Centre for Biological Sciences
Barry W. Connors
Barry W. Connors Brown University
Hey Kyoung Lee
Hey Kyoung Lee Johns Hopkins University
Randi J Hagerman
Randi J Hagerman University of California, Davis

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