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Neuroscience

D-Index
85
Citations
32623
World Ranking
1318
National Ranking
68

Research.com Recognitions

  • 2006 - Fellow of the Royal Society of Canada Academy of Science

Overview

Yu Tian Wang is affiliated with the University of British Columbia in Canada, focusing on research in medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including molecular biology, cellular and molecular neuroscience, neurology, plant science, and physiology.

Their research covers key topics such as neuroscience and neuropharmacology research, neuroinflammation and neurodegeneration mechanisms, receptor mechanisms and signaling, tryptophan and brain disorders, ion channel regulation and function, memory and neural mechanisms, and genetics and neurodevelopmental disorders.

Recent publications reflect this broad interest and include the following works:

  • NMDARs in Cell Survival and Death: Implications in Stroke Pathogenesis and Treatment (2020, Trends in Molecular Medicine)
  • TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease (2020, Aging Cell)
  • Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression (2020, Molecular Brain)
  • Mitochondrial dysfunction triggers the pathogenesis of Parkinson's disease in neuronal C/EBPβ transgenic mice (2021, Molecular Psychiatry)
  • GluA1-homomeric AMPA receptor in synaptic plasticity and neurological diseases (2021, Neuropharmacology)

Yu Tian Wang frequently collaborates with several co-authors, including:

  • Zhifang Dong
  • Lidong Liu
  • Yehong Du
  • Yang Ge
  • Yayan Pang

Their work has been published in multiple venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Neuropharmacology
  • Nature Communications
  • Frontiers in Pharmacology

Yu Tian Wang received recognition as a Fellow of the Royal Society of Canada in 2006, awarded by the Academy of Science.

Best Publications

  • Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity

    Lidong Liu;Tak Pan Wong;Mario F. Pozza;Kurt Lingenhoehl

  • Receptor trafficking and synaptic plasticity

    Graham L. Collingridge;Graham L. Collingridge;John T. R. Isaac;John T. R. Isaac;Yu Tian Wang

  • Treatment of Ischemic Brain Damage by Perturbing NMDA Receptor- PSD-95 Protein Interactions

    Michelle Aarts;Yitao Liu;Lidong Liu;Shintaro Besshoh

  • Excitotoxicity and stroke: identifying novel targets for neuroprotection.

    Ted Weita Lai;Shu Zhang;Yu Tian Wang

  • Activation of Synaptic NMDA Receptors Induces Membrane Insertion of New AMPA Receptors and LTP in Cultured Hippocampal Neurons

    Wei-Yang Lu;Heng-Ye Man;William Ju;William S. Trimble

  • Long-term depression in the CNS

    Graham L. Collingridge;Stephane Peineau;John G. Howland;Yu Tian Wang;Yu Tian Wang

  • NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

    Yitao Liu;Tak Pan Wong;Michelle Aarts;Amanda Rooyakkers

  • Regulation of NMDA receptors by tyrosine kinases and phosphatases.

    Yu Tian Wang;Michael W. Salter

  • Regulation of AMPA Receptor–Mediated Synaptic Transmission by Clathrin-Dependent Receptor Internalization

    Heng-Ye Man;Jerry W. Lin;William H. Ju;Gholamreza Ahmadian

  • LTP inhibits LTD in the hippocampus via regulation of GSK3beta.

    Stéphane Peineau;Changiz Taghibiglou;Clarrisa Bradley;Tak Pan Wong

  • Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy

    Patrick Cossette;Lidong Liu;Katéri Brisebois;Haiheng Dong;Haiheng Dong

  • Dual Regulation of NMDA Receptor Functions by Direct Protein-Protein Interactions with the Dopamine D1 Receptor

    Frank J.S. Lee;Sheng Xue;Lin Pei;Brian Vukusic

  • Differential Roles of NR2A- and NR2B-Containing NMDA Receptors in Ras-ERK Signaling and AMPA Receptor Trafficking

    Myung Jong Kim;Anthone W. Dunah;Yu Tian Wang;Morgan Sheng

  • Recruitment of functional GABA A receptors to postsynaptic domains by insulin

    Q. Wan;Z. G. Xiong;H. Y. Man;C. A. Ackerley

  • Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

    Jerry W. Lin;William Ju;Kelly Foster;Kelly Foster;Sang Hyoung Lee;Sang Hyoung Lee

  • Expression of Cerebellar Long-Term Depression Requires Postsynaptic Clathrin-Mediated Endocytosis

    Yu Tian Wang;David J. Linden

  • Direct protein–protein coupling enables cross-talk between dopamine D5 and γ-aminobutyric acid A receptors

    Fang Liu;Qi Wan;Zdenek B. Pristupa;Xian-Min Yu

  • Clathrin Adaptor AP2 and NSF Interact with Overlapping Sites of GluR2 and Play Distinct Roles in AMPA Receptor Trafficking and Hippocampal LTD

    Sang Hyoung Lee;Lidong Liu;Lidong Liu;Yu Tian Wang;Yu Tian Wang;Morgan Sheng

  • Glycine binding primes NMDA receptor internalization

    Yi Nong;Yue-Qiao Huang;William Ju;Lorraine V. Kalia

  • A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin

    Oliver Prange;Tak Pan Wong;Kimberly Gerrow;Yu Tian Wang

Frequent Co-Authors

Tak Pan Wong
Tak Pan Wong McGill University
Anthony G. Phillips
Anthony G. Phillips University of British Columbia
Michael W. Salter
Michael W. Salter University of Toronto
Fang Liu
Fang Liu Centre for Addiction and Mental Health
Graham L. Collingridge
Graham L. Collingridge Lunenfeld-Tanenbaum Research Institute
Morgan Sheng
Morgan Sheng Broad Institute
Ann Marie Craig
Ann Marie Craig University of British Columbia
Max S. Cynader
Max S. Cynader University of British Columbia
Michael Tymianski
Michael Tymianski University Health Network
Weihong Song
Weihong Song University of British Columbia

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