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Neuroscience

D-Index
55
Citations
13587
World Ranking
4657
National Ranking
2098

Overview

Benjamin D. Philpot is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, and neuroscience, covering a wide range of topics related to genetic syndromes, neurodevelopmental disorders, and neural dynamics.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Within these areas, specific subfields have been explored extensively, such as:

  • Genetics
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Pediatrics, Perinatology and Child Health

The principal topics of their work include:

  • Genetic Syndromes and Imprinting
  • Neuroscience and Neuropharmacology Research
  • Genetics and Neurodevelopmental Disorders
  • Neural dynamics and brain function
  • Epigenetics and DNA Methylation
  • Photoreceptor and optogenetics research
  • Congenital heart defects research

Benjamin D. Philpot has collaborated frequently with colleagues such as A Burette, Mark J. Zylka, Matthew C. Judson, Jeremy M. Simon, and Hyojin Kim, with these coauthors contributing to numerous publications.

Notable recent papers include:

  • A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder, 2020, Nature Neuroscience
  • Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research, 2020, Genetics
  • Region and Cell Type Distribution of TCF4 in the Postnatal Mouse Brain, 2020, Frontiers in Neuroanatomy
  • Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice, 2021, JCI Insight
  • Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity, 2020, UNC Libraries

Their work has been published extensively in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Neuroanatomy, JCI Insight, and the Journal of Neurodevelopmental Disorders.

Best Publications

  • Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity.

    Koji Yashiro;Benjamin D. Philpot

  • Conditional Knock-Out of Kir4.1 Leads to Glial Membrane Depolarization, Inhibition of Potassium and Glutamate Uptake, and Enhanced Short-Term Synaptic Potentiation

    Biljana Djukic;Kristen B. Casper;Benjamin D. Philpot;Lih Shen Chin

  • Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo

    Elizabeth M. Quinlan;Benjamin D. Philpot;Richard L. Huganir;Mark F. Bear

  • Internalization of ionotropic glutamate receptors in response to mGluR activation.

    Eric M. Snyder;Benjamin D. Philpot;Kimberly M. Huber;Xin Dong

  • Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

    Xiaoming Wang;Portia A. McCoy;Ramona M. Rodriguiz;Yanzhen Pan

  • Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory.

    Hongkui Zeng;Sumantra Chattarji;Sumantra Chattarji;Michaela Barbarosie;Laure Rondi-Reig

  • NMDA receptor-dependent ocular dominance plasticity in adult visual cortex.

    Nathaniel B Sawtell;Mikhail Y Frenkel;Benjamin D Philpot;Kazu Nakazawa

  • Visual Experience and Deprivation Bidirectionally Modify the Composition and Function of NMDA Receptors in Visual Cortex

    Benjamin D. Philpot;Aarti K. Sekhar;Harel Z. Shouval;Mark F. Bear

  • Topoisomerases facilitate transcription of long genes linked to autism

    Ian F. King;Chandri N. Yandava;Angela M. Mabb;Jack S. Hsiao

  • Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.

    Hsien Sung Huang;John A. Allen;Angela M. Mabb;Ian F. King

  • Ube3a is required for experience-dependent maturation of the neocortex

    Koji Yashiro;Koji Yashiro;Thorfinn T Riday;Kathryn H Condon;Adam C Roberts

  • Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes.

    Angela M. Mabb;Matthew C. Judson;Mark J. Zylka;Benjamin D. Philpot

  • Transsynaptic Signaling by Activity-Dependent Cleavage of Neuroligin-1

    Rui T. Peixoto;Portia A. Kunz;Hyungbae Kwon;Angela M. Mabb

  • Obligatory Role of NR2A for Metaplasticity in Visual Cortex

    Benjamin D. Philpot;Kathleen K.A. Cho;Mark F. Bear

  • Evidence for Altered NMDA Receptor Function as a Basis for Metaplasticity in Visual Cortex

    Benjamin D. Philpot;Juan S. Espinosa;Mark F. Bear

  • Influence of the NR3A subunit on NMDA receptor functions

    Maile A. Henson;Adam C. Roberts;Isabel Pérez-Otaño;Benjamin D. Philpot

  • Maternal Loss of Ube3a Produces an Excitatory/Inhibitory Imbalance through Neuron Type-Specific Synaptic Defects

    Michael L. Wallace;Alain C. Burette;Richard J. Weinberg;Benjamin D. Philpot

  • Presynaptic NMDA Receptors: Newly Appreciated Roles in Cortical Synaptic Function and Plasticity

    Rebekah Corlew;Daniel J. Brasier;Daniel E. Feldman;Benjamin D. Philpot

  • Developmental Switch in the Contribution of Presynaptic and Postsynaptic NMDA Receptors to Long-Term Depression

    Rebekah Corlew;Yun Wang;Haben Ghermazien;Alev Erisir

  • Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation

    Adam C. Roberts;Javier Díez-García;Ramona M. Rodriguiz;Iciar Paula López

  • Conditional knock-out of K(ir)4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic Potentiation

    Biljana Djukic;Kristen B. Casper;Benjamin D. Philpot;Lih-Shen Chin

Frequent Co-Authors

Richard J. Weinberg
Richard J. Weinberg University of North Carolina at Chapel Hill
Michael D. Ehlers
Michael D. Ehlers MPM BioImpact
Ype Elgersma
Ype Elgersma Erasmus University Rotterdam
Sheryl S. Moy
Sheryl S. Moy University of North Carolina at Chapel Hill
J. David Sweatt
J. David Sweatt University of Alabama at Birmingham
Fernando Pardo-Manuel de Villena
Fernando Pardo-Manuel de Villena University of North Carolina at Chapel Hill
David W. Threadgill
David W. Threadgill Texas A&M University
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill

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Related Online Degrees & Career Pathways

Exploring neuroscience often leads students toward varied career pathways in mental health, research, and therapy. Many related disciplines offer flexible online degree options, allowing learners to balance education with personal commitments.

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Each pathway complements neuroscience by strengthening your interdisciplinary knowledge and expanding your career opportunities in research, therapy, or social services.

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