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Jan G. J. van de Winkel

Jan G. J. van de Winkel

D-Index & Metrics

Immunology

D-Index
91
Citations
28123
World Ranking
1046
National Ranking
565

Overview

Jan G. J. van de Winkel is affiliated with Genmab in the United States. Their professional focus is reflected through their association with this organization, which is known for its work in biotechnology and pharmaceutical research.

There are no records of recent publications, co-authors, or specific fields and subfields of study associated with Jan G. J. van de Winkel in the available data. Similarly, there are no listed awards or book publications attributed to this scientist in the current dataset.

The absence of data on main topics of work, frequent publication venues, or notable collaborations limits the detailed analysis of their research focus and academic impact. However, the connection to Genmab indicates involvement in applied biomedical research or related scientific endeavors.

The profile is based solely on the verified affiliation information, providing a factual representation without assumptions about the scope or nature of their research activities.

Best Publications

  • Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors

    Michel De Weers;Yu Tzu Tai;Michael S. Van Der Veer;Joost M. Bakker

  • Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

    Marijn van der Neut Kolfschoten;Janine Schuurman;Mario Losen;Wim K. Bleeker

  • Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications.

    Jan G.J. van de Winkel;Peter J.A. Capel

  • Complement is activated by IgG hexamers assembled at the cell surface.

    Christoph A. Diebolder;Christoph A. Diebolder;Frank J. Beurskens;Rob N. de Jong;Roman I. Koning

  • Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas

    Jessica L Teeling;Ruth R French;Mark S Cragg;Jeroen van den Brakel

  • The Biological Activity of Human CD20 Monoclonal Antibodies Is Linked to Unique Epitopes on CD20

    Jessica L. Teeling;Wendy J.M. Mackus;Luus J.J.M. Wiegman;Jeroen H.N. van den Brakel

  • Human monoclonal antibodies against cd20

    Jessica Woodmill Cottage Teeling;Sigrid Ruuls;Martin Glennie;Jan G. J. Van De Winkel

  • Impaired IgG-Dependent Anaphylaxis and Arthus Reaction in FcγRIII (CD16) Deficient Mice

    Wouter L.W Hazenbos;J.Engelbert Gessner;Frans M.A Hofhuis;Henri Kuipers

  • Effector Function Activities of a Panel of Mutants of a Broadly Neutralizing Antibody against Human Immunodeficiency Virus Type 1

    Marjan Hezareh;Ann J. Hessell;Richard C. Jensen;Jan G. J. van de Winkel

  • On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2.

    P. W. H. I. Parren;P. A. M. Warmerdam;L. C. M. Boeije;J. Arts

  • Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

    Aran F Labrijn;Antonio Ortiz Buijsse;Ewald T J van den Bremer;Annemiek Y W Verwilligen

  • Fc gamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus - Contribution of FCGR2B to genetic susceptibility

    Chieko Kyogoku;Hilde M. Dijstelbloem;Naoyuki Tsuchiya;Yoko Hatta

  • IgA and the IgA Fc receptor.

    Marjolein van Egmond;Cora A Damen;Annemiek B van Spriel;Gestur Vidarsson

  • Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange

    Aran F. Labrijn;Joyce I. Meesters;Bart E. C. G. de Goeij;Ewald T. J. van den Bremer

  • Targeting interleukin‐15 in patients with rheumatoid arthritis: A proof‐of‐concept study

    Bo Baslund;Niels Tvede;Bente Danneskiold-Samsoe;Per Larsson

  • Heterodimeric antibody fc-containing proteins and methods for production thereof

    Aran Frank Labrijn;Joyce I. Meesters;Ewald T. J. Van Den Bremer;Joost J. Neijssen

  • Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX.

    Andrew W. Pawluczkowycz;Frank J. Beurskens;Paul V. Beum;Margaret A. Lindorfer

  • Clinical significance of IgG Fc receptors and FcγR-directed immunotherapies

    Yashwant M. Deo;Robert F. Graziano;Roland Repp;Jan G.J. van de Winkel

  • Recombinant monovalent antibodies and methods for production thereof

    Paul Parren;Janine Schuurman;Tom Vink;Willem Karel Bleeker

  • Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

    Tanja Schneider-Merck;Jeroen J. Lammerts van Bueren;Sven Berger;Kai Rossen

Frequent Co-Authors

Paul W. H. I. Parren
Paul W. H. I. Parren Leiden University Medical Center
Jeanette H. W. Leusen
Jeanette H. W. Leusen Utrecht University
Thomas Valerius
Thomas Valerius Kiel University
Ole Baadsgaard
Ole Baadsgaard Genmab (United States)
Matthias Peipp
Matthias Peipp Kiel University
Marjolein van Egmond
Marjolein van Egmond VU University Medical Center
Gestur Vidarsson
Gestur Vidarsson University of Amsterdam
Ronald P. Taylor
Ronald P. Taylor University of Virginia
Margaret A. Lindorfer
Margaret A. Lindorfer University of Virginia
Martin J. Glennie
Martin J. Glennie University of Southampton

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