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Immunology
USA
2025

D-Index & Metrics

Immunology

D-Index
139
Citations
86876
World Ranking
166
National Ranking
111

Research.com Recognitions

  • 2025 - Research.com Immunology in United States Leader Award
  • 2018 - Robert Koch Prize
  • 2012 - Canada Gairdner International Award
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2008 - Fellow of the American Academy of Arts and Sciences
  • 2007 - Member of the National Academy of Medicine (NAM)
  • 2006 - Member of the National Academy of Sciences

Overview

Jeffrey V. Ravetch is affiliated with Rockefeller University in the United States. Their research primarily focuses on immunology and medicine, with significant contributions to the fields of immunology and microbiology. Within these broader areas, their work spans subfields including immunology, radiology, nuclear medicine and imaging, molecular biology, oncology, and infectious diseases.

Their main research topics include monoclonal and polyclonal antibodies research, glycosylation and glycoproteins research, immune cell function and interaction, cancer immunotherapy and biomarkers, immunotherapy and immune responses, galectins and cancer biology, and T-cell and B-cell immunology.

Recent papers authored or co-authored by Ravetch include:

  • The role of IgG Fc receptors in antibody-dependent enhancement (2020, Nature Reviews Immunology)
  • Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo (2020, The Journal of Experimental Medicine)
  • Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 (2020, Proceedings of the National Academy of Sciences)
  • Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function (2020, Cancer Research)
  • Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy (2021, Nature)

Frequent coauthors working with Ravetch include:

  • Stylianos Bournazos
  • David A. Knorr
  • Juan C. Osorio
  • Kevin S. Kao
  • Patrick Smith

Ravetch has published extensively in prominent scientific venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Regular and Young Investigator Award Abstracts, Cancer Research, and Neuro-Oncology.

The scientist's professional recognition includes election as a Fellow of the American Academy of Arts and Sciences in 2008, a Fellow of the American Association for the Advancement of Science (AAAS) also in 2008, and membership in the National Academy of Medicine (NAM) since 2007 and the National Academy of Sciences since 2006.

They have also been awarded the Canada Gairdner International Award in 2012 and the Robert Koch Prize in 2018.

Best Publications

  • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets.

    Raphael A. Clynes;Terri L. Towers;Leonard G. Presta;Jeffrey V. Ravetch

  • Fcγ receptors as regulators of immune responses

    Falk Nimmerjahn;Jeffrey V. Ravetch

  • Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

    Daniel Hawiger;Kayo Inaba;Kayo Inaba;Yair Dorsett;Ming Guo

  • IgG Fc Receptors

    Jeffrey V. Ravetch;Silvia Bolland

  • Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

    Yoshikatsu Kaneko;Falk Nimmerjahn;Jeffrey V. Ravetch

  • Immune inhibitory receptors.

    Jeffrey V. Ravetch;Lewis L. Lanier

  • Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

    Tyler R. Simpson;Fubin Li;Welby Montalvo-Ortiz;Manuel A. Sepulveda

  • Fcγ Receptors: Old Friends and New Family Members

    Falk Nimmerjahn;Jeffrey V. Ravetch

  • Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding

    Falk Nimmerjahn;Jeffrey V. Ravetch

  • Anti-inflammatory Activity of IVIG Mediated Through the Inhibitory Fc Receptor

    Astrid Samuelsson;Terri L. Towers;Jeffrey V. Ravetch

  • γ -Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

    Andrew D. Luster;Jay C. Unkeless;Jeffrey V. Ravetch

  • FcR γ chain deletion results in pleiotrophic effector cell defects

    Toshiyuki Takai;Min Li;Diana Sylvestre;Raphael Clynes

  • Structure of the human immunoglobulin mu locus: characterization of embryonic and rearranged J and D genes.

    Jeffrey V. Ravetch;Ulrich Siebenlist;Stanley Korsmeyer;Thomas Waldmann

  • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

    Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Michael S. Seaman

  • Augmented humoral and anaphylactic responses in FcγRII-deficient mice

    Toshiyuki Takai;Masao Ono;Masaki Hikida;Hitoshi Ohmori

  • The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy

    Junji Uchida;Yasuhito Hamaguchi;Julie A. Oliver;Jeffrey V. Ravetch

  • Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

    Robert M. Anthony;Falk Nimmerjahn;Falk Nimmerjahn;David J. Ashline;Vernon N. Reinhold

  • Uncoupling of Immune Complex Formation and Kidney Damage in Autoimmune Glomerulonephritis

    Raphael Clynes;Calin Dumitru;Jeffrey V. Ravetch

  • Spontaneous Autoimmune Disease in FcγRIIB-Deficient Mice Results from Strain-Specific Epistasis

    Silvia Bolland;Jeffrey V Ravetch

  • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

    Masao Ono;Silvia Bolland;Silvia Bolland;Paul Tempst;Jeffrey V. Ravetch;Jeffrey V. Ravetch

  • FcγRIV : A novel FcR with distinct IgG subclass specificity

    Falk Nimmerjahn;Pierre Bruhns;Ken Horiuchi;Jeffrey V. Ravetch

  • Fc receptors.

    Unknown

Frequent Co-Authors

Falk Nimmerjahn
Falk Nimmerjahn University of Erlangen-Nuremberg
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Silvia Bolland
Silvia Bolland National Institute of Allergy and Infectious Diseases
Raphael Clynes
Raphael Clynes Columbia University
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Toshiyuki Takai
Toshiyuki Takai Tohoku University
Ralph M. Steinman
Ralph M. Steinman Rockefeller University
Andrew D. Luster
Andrew D. Luster Harvard University
Michael Lanzer
Michael Lanzer University Hospital Heidelberg
Philip Leder
Philip Leder Harvard University

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