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Biology and Biochemistry

D-Index
56
Citations
10413
World Ranking
14508
National Ranking
1030

Overview

Michael Lanzer is affiliated with the University Hospital Heidelberg in Germany, where their research primarily focuses on topics related to malaria and molecular biology. Their scholarly output covers various aspects of infectious diseases, with a significant emphasis on malaria research and control.

The main fields of study for Michael Lanzer include Medicine and Biochemistry, Genetics and Molecular Biology, supported by numerous publications in these areas. Within these fields, their work extends into subfields such as Public Health, Environmental and Occupational Health, Molecular Biology, Genetics, Oncology, and Immunology.

The scientist's research explores several main topics, including:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Lipid Membrane Structure and Behavior
  • Drug Transport and Resistance Mechanisms
  • Hemoglobinopathies and Related Disorders
  • Venomous Animal Envenomation and Studies
  • Erythrocyte Function and Pathophysiology

Michael Lanzer has published multiple recent papers, contributing to a range of journals and scientific venues. Notable recent publications include:

  • "Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial," 2020, npj Vaccines
  • "Structure of the merozoite surface protein 1 from Plasmodium falciparum," 2021, Science Advances
  • "The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum," 2022, Microbiology Spectrum
  • "PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport," 2023, PLoS Pathogens
  • "The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake," 2023, Proceedings of the National Academy of Sciences

Frequent co-authors in Michael Lanzer's research collaborations include:

  • Cecília P. Sanchez
  • Ulrich S. Schwarz
  • Marek Cyrklaff
  • Pintu Patra
  • Kristin Fürle

Michael Lanzer's work appears regularly in several publication venues, with multiple papers featured in:

  • Methods in Molecular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Vaccines
  • Biophysical Journal
  • Science Advances

Best Publications

  • Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra‐erythrocytic development in Plasmodium falciparum

    A. Scherf;R. Hernandez‐Rivas;P. Buffet;E. Bottius

  • Promoters largely determine the efficiency of repressor action

    Michael Lanzer;Hermann Bujard

  • A T5 promoter-based transcription-translation system for the analysis of proteins in vitro and in vivo

    Hermann Bujard;Reiner Gentz;Michael Lanzer;Dietrich Stueber

  • Drug-resistant malaria: molecular mechanisms and implications for public health.

    Ines Petersen;Richard Eastman;Michael Lanzer

  • stevor and rif are Plasmodium falciparum multicopy gene families which potentially encode variant antigens.

    Qin Cheng;Nicole Cloonan;Katja Fischer;Jenny Thompson

  • A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax

    Hernando A. del Portillo;Carmen Fernandez-Becerra;Sharen Bowman;Karen Oliver

  • Hemoglobins S and C interfere with actin remodeling in Plasmodium falciparum-infected erythrocytes.

    Marek Cyrklaff;Cecilia P. Sanchez;Nicole Kilian;Cyrille Bisseye

  • A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A

    Nicola K Viebig;Benoit Gamain;Christine Scheidig;Catherine Lépolard

  • Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

    Petra Rohrbach;Cecilia P Sanchez;Karen Hayton;Oliver Friedrich

  • Maurer's clefts: A novel multi-functional organelle in the cytoplasm of Plasmodium falciparum-infected erythrocytes

    Michael Lanzer;Hannes Wickert;Georg Krohne;Laetitia Vincensini

  • Trafficking of STEVOR to the Maurer's clefts in Plasmodium falciparum-infected erythrocytes.

    Jude M Przyborski;Susanne K Miller;Judith M Pfahler;Philipp P Henrich

  • Transporters as mediators of drug resistance in Plasmodium falciparum

    Cecilia P. Sanchez;Anurag Dave;Wilfred D. Stein;Michael Lanzer

  • Quantitative pH measurements in Plasmodium falciparum-infected erythrocytes using pHluorin

    Yvonne Kuhn;Petra Rohrbach;Michael Lanzer

  • Subregions of a conserved part of the HIV gp41 transmembrane protein are differentially recognized by antibodies of infected individuals.

    U Certa;W Bannwarth;D Stüber;R Gentz

  • Differential Stimulation of the Na+/H+ Exchanger Determines Chloroquine Uptake in Plasmodium falciparum

    Stefan Wünsch;Cecilia P. Sanchez;Michael Gekle;Lars Große-Wortmann

  • Identification of a Chloroquine Importer in Plasmodium falciparum DIFFERENCES IN IMPORT KINETICS ARE GENETICALLY LINKED WITH THE CHLOROQUINE-RESISTANT PHENOTYPE

    Cecilia P. Sanchez;Stefan Wünsch;Michael Lanzer

  • Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum.

    Cecilia P. Sanchez;Alexander Rotmann;Wilfred D. Stein;Michael Lanzer

  • Control of gene expression in Plasmodium falciparum

    Paul Horrocks;Koen Dechering;Koen Dechering;Michael Lanzer

  • Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum.

    Cecilia P. Sanchez;Wilfred Stein;Michael Lanzer

  • Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites.

    Tobias Müller;Laure Johann;Beate Jannack;Margit Brückner

Frequent Co-Authors

Wilfred D. Stein
Wilfred D. Stein Hebrew University of Jerusalem
Katherine Thea Andrews
Katherine Thea Andrews Griffith University
Motomu Tanaka
Motomu Tanaka Heidelberg University
Friedrich Frischknecht
Friedrich Frischknecht Heidelberg University
Ulrich S. Schwarz
Ulrich S. Schwarz Heidelberg University
Georg Krohne
Georg Krohne University of Würzburg
Brendan S. Crabb
Brendan S. Crabb Monash University
David A. Fidock
David A. Fidock Columbia University
Artur Scherf
Artur Scherf Institut Pasteur
Vanessa Yardley
Vanessa Yardley London School of Hygiene & Tropical Medicine

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