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Genetics

D-Index
83
Citations
27720
World Ranking
1410
National Ranking
666

Research.com Recognitions

  • 2020 - Fellow of the American Academy of Arts and Sciences
  • 2011 - Fellow of the American Society of Tropical Medicine and Hygiene (ASTMH)
  • 2010 - Member of the National Academy of Medicine (NAM)
  • 2007 - Member of the National Academy of Sciences
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Thomas E. Wellems is affiliated with the National Institutes of Health in the United States. Their work spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Public Health, Environmental and Occupational Health, Molecular Biology, Infectious Diseases, Epidemiology, and Computational Theory and Mathematics.

The scientist's main research topics include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Computational Drug Discovery Methods
  • HIV/AIDS drug development and treatment
  • Aquaculture disease management and microbiota
  • Trypanosoma species research and implications
  • Viral Infections and Vectors

Thomas E. Wellems has contributed to various journals, frequently publishing in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antimicrobial Agents and Chemotherapy
  • Proceedings of the National Academy of Sciences
  • Malaria Journal
  • PLoS neglected tropical diseases

Recent papers authored or co-authored by them include:

  • 'Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression' (2020) published in PLoS Biology
  • 'Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development' (2021) published in Proceedings of the National Academy of Sciences
  • 'An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples' (2022) published in Wellcome Open Research
  • 'Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum' (2020) published in Malaria Journal
  • 'Artemisinin Resistance': Something New or Old? Something of a Misnomer?' (2020) published in Trends in Parasitology

Frequent co-authors in their research collaborations include:

  • Juliana M. Sá
  • Shuchi Amin
  • Angela C. Ellis
  • David Serre
  • Tales Vicari Pascini

Thomas E. Wellems has received several recognitions, including:

  • Fellow of the American Academy of Arts and Sciences (2020)
  • Fellow of the American Society of Tropical Medicine and Hygiene (ASTMH) (2011)
  • Member of the National Academy of Medicine (NAM) (2010)
  • Member of the National Academy of Sciences (2007)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2006)
  • Member of the Association of American Physicians

Best Publications

  • Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

    David A. Fidock;Takashi Nomura;Angela K. Talley;Roland A. Cooper

  • The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

    Xin zhuan Su;Virginia M. Heatwole;Samuel P. Wertheimer;Frangoise Guinet

  • A molecular marker for chloroquine-resistant falciparum malaria.

    Abdoulaye Djimdé;Ogobara K. Doumbo;Joseph F. Cortese;Kassoum Kayentao

  • Chloroquine-Resistant Malaria

    Thomas E. Wellems;Christopher V. Plowe

  • Genetic analysis of the human malaria parasite plasmodium falciparum

    David Walliker;Isabella A. Quakyi;Thomas E. Wellems;Thomas F. McCutchan

  • Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

    David S. Peterson;David Walliker;Thomas E. Wellems

  • Pyrimethamine and Proguanil Resistance-Conferring Mutations in Plasmodium falciparum Dihydrofolate Reductase: Polymerase Chain Reaction Methods for Surveillance in Africa

    Christopher V. Plowe;Abdoulaye Djimde;Madama Bouare;Ogobara Doumbo

  • Malaria biology and disease pathogenesis: insights for new treatments.

    Louis H Miller;Hans C Ackerman;Xin-zhuan Su;Thomas E Wellems

  • Chloroquine resistance not linked to mdr -like genes in a Plasmodium falciparum cross

    T. E. Wellems;L. J. Panton;I. Y. Gluzman;V. E. do Rosario

  • Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum

    Lúcio H. Freitas-Junior;Emmanuel Bottius;Lindsay A. Pirrit;Kirk W. Deitsch

  • Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.

    David S. Peterson;Wilbur K. Milhous;Thomas E. Wellems

  • Complex Polymorphisms in an ∼330 kDa Protein Are Linked to Chloroquine-Resistant P. falciparum in Southeast Asia and Africa

    Xin-zhuan Su;Laura A. Kirkman;Hisashi Fujioka;Thomas E. Wellems

  • Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine

    Yimin Wu;Laura A. Kirkman;Thomas E. Wellems

  • Transfection of Plasmodium falciparum within human red blood cells.

    Yimin Wu;C. D. Sifri;Hsien-Hsien Lei;Xin-Zhuan Su

  • Transformation of malaria parasites by the spontaneous uptake and expression of DNA from human erythrocytes

    Kirk W. Deitsch;Casey L. Driskill;Thomas E. Wellems

  • Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7.

    Thomas E. Wellems;Annie Walker-Jonah;Lindsey J. Panton

  • Plasmodium biology: genomic gleanings.

    L Aravind;Lakshminarayan M Iyer;Thomas E Wellems;Louis H Miller

  • Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes

    R J Howard;S Uni;M Aikawa;S B Aley

  • A Genetic Map and Recombination Parameters of the Human Malaria Parasite Plasmodium falciparum

    Xin-zhuan Su;Michael T. Ferdig;Yaming Huang;Chuong Q. Huynh

  • The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites.

    John H. Adams;Dlana E. Hudson;Motomi Torii;Gary E. Ward

Frequent Co-Authors

Xin-zhuan Su
Xin-zhuan Su National Institutes of Health
Rick M. Fairhurst
Rick M. Fairhurst AstraZeneca (United Kingdom)
Christopher V. Plowe
Christopher V. Plowe University of Maryland, Baltimore
David A. Fidock
David A. Fidock Columbia University
Jianbing Mu
Jianbing Mu National Institutes of Health
Ogobara K. Doumbo
Ogobara K. Doumbo University of Bamako
Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Kirk W. Deitsch
Kirk W. Deitsch Cornell University
Louis H. Miller
Louis H. Miller National Institute of Allergy and Infectious Diseases
Olivo Miotto
Olivo Miotto Mahidol University

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