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Immunology

D-Index
73
Citations
20102
World Ranking
2130
National Ranking
85

Overview

Theo Rispens is affiliated with the University of Amsterdam in the Netherlands and specializes in research primarily within Medicine, Immunology, and Microbiology. Their work focuses extensively on Immunology and Infectious Diseases, with additional contributions in Radiology, Nuclear Medicine and Imaging, Rheumatology, and Molecular Biology.

Their research topics cover a range of areas, including:

  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • COVID-19 Clinical Research Studies
  • T-cell and B-cell Immunology
  • Systemic Lupus Erythematosus Research
  • Multiple Sclerosis Research Studies
  • Rheumatoid Arthritis Research and Therapies

Theo Rispens has published in multiple venues, with frequent contributions to:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • The Journal of Immunology
  • RMD Open

Among recent publications, the following papers are notable:

  • "Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity" (2020, Science)
  • "MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation" (2020, Frontiers in Immunology)
  • "High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages" (2021, Science Translational Medicine)
  • "The unique properties of IgG4 and its roles in health and disease" (2023, Nature Reviews Immunology)
  • "FcγR Binding and ADCC Activity of Human IgG Allotypes" (2020, Frontiers in Immunology)

Frequent co-authors collaborating with Theo Rispens include:

  • Gertjan Wolbink
  • Maurice Steenhuis
  • S. Marieke van Ham
  • Anja ten Brinke
  • Taco W. Kuijpers

Best Publications

  • IgG subclasses and allotypes: from structure to effector functions.

    Gestur Vidarsson;Gillian Dekkers;Theo Rispens

  • Immunoglobulin G4: an odd antibody

    R. C. Aalberse;S. O. Stapel;J. Schuurman;T. Rispens

  • Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis.

    Pauline A. van Schouwenburg;Theo Rispens;Gerrit Jan Wolbink

  • Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis

    Johannan F. Brandse;Gijs R. van den Brink;Manon E. Wildenberg;Desiree van der Kleij

  • MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation

    Thomas Sénard;Andrea F. G. Gargano;Andrea F. G. Gargano;David Falck;Steven W. de Taeye

  • Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.

    Mads Delbo Larsen;Erik L. de Graaf;Myrthe E. Sonneveld;H. Rosina Plomp

  • Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities.

    Gillian Dekkers;Louise Treffers;Rosina Plomp;Arthur E H Bentlage

  • The Emerging Importance of IgG Fab Glycosylation in Immunity.

    Fleur S. van de Bovenkamp;Lise Hafkenscheid;Theo Rispens;Yoann Rombouts;Yoann Rombouts

  • Affinity of human IgG subclasses to mouse Fc gamma receptors

    Gillian Dekkers;Arthur E. H. Bentlage;Tamara C. Stegmann;Heather L. Howie

  • Key findings towards optimising adalimumab treatment: the concentration–effect curve

    Mieke F Pouw;Charlotte L Krieckaert;Michael T Nurmohamed;Desiree van der Kleij

  • Detection of infliximab levels and anti-infliximab antibodies: a comparison of three different assays

    N. Vande Casteele;D. J. Buurman;M. G. G. Sturkenboom;J. H. Kleibeuker

  • Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation

    Pauline A van Schouwenburg;Lotte A van de Stadt;Rob N de Jong;Esther E L van Buren

  • Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis

    Yoann Rombouts;Annemiek Willemze;Joyce J B C van Beers;Jing Shi

  • A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

    Rick Kapur;Iwan Kustiawan;Anne Vestrheim;Anne Vestrheim;Carolien A. M. Koeleman

  • High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.

    Willianne Hoepel;Hung Jen Chen;Chiara E. Geyer;Sona Allahverdiyeva

  • Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis

    Johannan F. Brandse;Ron A. Mathôt;Desiree van der Kleij;Theo Rispens

  • Differential effect of drug interference in immunogenicity assays

    Margreet H. Hart;Henk de Vrieze;Diana Wouters;Gerrit-Jan Wolbink

  • Mechanism of immunoglobulin G4 Fab-arm exchange.

    Theo Rispens;Pleuni Ooijevaar-de Heer;Onno Bende;Rob C. Aalberse

  • FcγR Binding and ADCC Activity of Human IgG Allotypes.

    Steven W. de Taeye;Arthur E. H. Bentlage;Mirjam M. Mebius;Joyce I. Meesters

  • Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages

    Lisa T. C. Vogelpoel;Ivo S. Hansen;Theo Rispens;Femke J. M. Muller

  • Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis

    Leendert A. Trouw;Theo Rispens;Rene E. M. Toes

Frequent Co-Authors

Gertjan Wolbink
Gertjan Wolbink University of Amsterdam
Rob C. Aalberse
Rob C. Aalberse University of Amsterdam
Gestur Vidarsson
Gestur Vidarsson University of Amsterdam
Michael T. Nurmohamed
Michael T. Nurmohamed University of Amsterdam
Manfred Wuhrer
Manfred Wuhrer Leiden University Medical Center
Taco W. Kuijpers
Taco W. Kuijpers University of Amsterdam
Eleanor Barnes
Eleanor Barnes University of Oxford
Lucien A. Aarden
Lucien A. Aarden University of Amsterdam
Geert R. D'Haens
Geert R. D'Haens University of Amsterdam
Brian J. Sutton
Brian J. Sutton King's College London

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