D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 69 Citations 22,706 147 World Ranking 1157 National Ranking 41

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Immune system

Lucien A. Aarden mostly deals with Immunology, Internal medicine, Antibody, Molecular biology and Monoclonal antibody. His work on Immunology deals in particular with Arthritis, Adalimumab, Monoclonal, Rheumatoid arthritis and Tumor necrosis factor alpha. As part of one scientific family, he deals mainly with the area of Internal medicine, narrowing it down to issues related to the Gastroenterology, and often Multiple organ dysfunction syndrome.

His work deals with themes such as Clinical state and Immune system, which intersect with Antibody. His research in Molecular biology intersects with topics in Cell culture, Lymphokine, DNA, Mitochondrial DNA and Serology. His Monoclonal antibody research is multidisciplinary, relying on both Biotinylation, Recombinant DNA, Virology, Synovial fluid and Horseradish peroxidase.

His most cited work include:

  • Production of hybridoma growth factor by human monocytes. (1017 citations)
  • Increased plasma levels of interleukin-6 in sepsis. (736 citations)
  • Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange (701 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, Molecular biology, Antibody, Internal medicine and Monoclonal antibody. His Immunology research focuses on Cytokine, Rheumatoid arthritis, Adalimumab, Antigen and Interleukin 6. The Molecular biology study combines topics in areas such as T cell, IL-2 receptor, Cell culture and DNA.

Antibody is often connected to Radioimmunoassay in his work. His research integrates issues of Gastroenterology and Endocrinology in his study of Internal medicine. His study looks at the intersection of Monoclonal antibody and topics like Receptor with Interleukin-6 receptor and CD32.

He most often published in these fields:

  • Immunology (52.66%)
  • Molecular biology (31.88%)
  • Antibody (28.50%)

What were the highlights of his more recent work (between 2006-2016)?

  • Immunology (52.66%)
  • Adalimumab (8.70%)
  • Antibody (28.50%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Immunology, Adalimumab, Antibody, Monoclonal antibody and Rheumatoid arthritis. Immunology connects with themes related to Internal medicine in his study. His Adalimumab research includes elements of Area under the curve, Arthritis, Monoclonal, Infliximab and Prospective cohort study.

His Antibody research incorporates elements of Interleukin 3, Interleukin 20, Interleukin 5 and Interleukin 6. His Monoclonal antibody study combines topics in areas such as Molecular biology, Pharmacokinetics and In vitro. His studies in Rheumatoid arthritis integrate themes in fields like Connective tissue disease and Immunopathology.

Between 2006 and 2016, his most popular works were:

  • Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange (701 citations)
  • Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. (574 citations)
  • Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis (472 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Immune system

Lucien A. Aarden spends much of his time researching Immunology, Adalimumab, Rheumatoid arthritis, Internal medicine and Antibody. Monoclonal antibody and Immunogenicity are the primary areas of interest in his Immunology study. Lucien A. Aarden has researched Adalimumab in several fields, including Immunopathology and Arthritis.

His Rheumatoid arthritis research incorporates themes from Connective tissue disease and Infliximab. His biological study deals with issues like Gastroenterology, which deal with fields such as Surgery and Methotrexate. His Antibody research integrates issues from Proinflammatory cytokine, Immune system and Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Production of hybridoma growth factor by human monocytes.

Lucien A. Aarden;Els R. De Groot;Otto L. Schaap;Peter M. Lansdorp.
European Journal of Immunology (1987)

1327 Citations

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways

S. J. H. Van Deventer;H. R. Buller;J. W. Ten Cate;L. A. Aarden.
Blood (1990)

1052 Citations

Increased plasma levels of interleukin-6 in sepsis [see comments]

CE Hack;ER De Groot;RJ Felt-Bersma;JH Nuijens.
Blood (1989)

1044 Citations

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production.

T. C. T. M. Van Der Pouw Kraan;L. C. M. Boeije;R. J. T. Smeenk;J. Wijdenes.
Journal of Experimental Medicine (1995)

996 Citations

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten;Janine Schuurman;Mario Losen;Wim K. Bleeker.
Science (2007)

802 Citations

IMMUNOLOGY OF DNA. III. CRITHIDIA LUCILIAE, A SIMPLE SUBSTRATE FOR THE DETERMINATION OF ANTI‐dsDNA WITH THE IMMUNOFLUORESCENCE TECHNIQUE*

L. A. Aarden;Els R. de Groot;T. E. W. Feltkamp.
Annals of the New York Academy of Sciences (1975)

769 Citations

Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up.

Geertje M. Bartelds;Charlotte L. M. Krieckaert;Michael T. Nurmohamed;Pauline A. van Schouwenburg.
JAMA (2011)

750 Citations

Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis

Geertje M Bartelds;Carla A Wijbrandts;Michael T Nurmohamed;Steven Stapel.
Annals of the Rheumatic Diseases (2007)

616 Citations

Functional discrimination between interleukin 6 and interleukin 1

Maarten Helle;Leonie Boeije And and;Lucien A. Aarden.
European Journal of Immunology (1988)

613 Citations

Serum levels of interleukin-6 and acute phase responses.

M.W.N. Nijsten;E.R. De Groot;H.J. Ten Duis;H.J. Klasen.
The Lancet (1987)

587 Citations

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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