D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 76 Citations 25,471 197 World Ranking 1187 National Ranking 43

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Immune system

Lucien A. Aarden mostly deals with Immunology, Internal medicine, Antibody, Molecular biology and Monoclonal antibody. His work on Immunology deals in particular with Arthritis, Adalimumab, Monoclonal, Rheumatoid arthritis and Tumor necrosis factor alpha. As part of one scientific family, he deals mainly with the area of Internal medicine, narrowing it down to issues related to the Gastroenterology, and often Multiple organ dysfunction syndrome.

His work deals with themes such as Clinical state and Immune system, which intersect with Antibody. His research in Molecular biology intersects with topics in Cell culture, Lymphokine, DNA, Mitochondrial DNA and Serology. His Monoclonal antibody research is multidisciplinary, relying on both Biotinylation, Recombinant DNA, Virology, Synovial fluid and Horseradish peroxidase.

His most cited work include:

  • Production of hybridoma growth factor by human monocytes. (1017 citations)
  • Increased plasma levels of interleukin-6 in sepsis. (736 citations)
  • Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange (701 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, Molecular biology, Antibody, Internal medicine and Monoclonal antibody. His Immunology research focuses on Cytokine, Rheumatoid arthritis, Adalimumab, Antigen and Interleukin 6. The Molecular biology study combines topics in areas such as T cell, IL-2 receptor, Cell culture and DNA.

Antibody is often connected to Radioimmunoassay in his work. His research integrates issues of Gastroenterology and Endocrinology in his study of Internal medicine. His study looks at the intersection of Monoclonal antibody and topics like Receptor with Interleukin-6 receptor and CD32.

He most often published in these fields:

  • Immunology (52.66%)
  • Molecular biology (31.88%)
  • Antibody (28.50%)

What were the highlights of his more recent work (between 2006-2016)?

  • Immunology (52.66%)
  • Adalimumab (8.70%)
  • Antibody (28.50%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Immunology, Adalimumab, Antibody, Monoclonal antibody and Rheumatoid arthritis. Immunology connects with themes related to Internal medicine in his study. His Adalimumab research includes elements of Area under the curve, Arthritis, Monoclonal, Infliximab and Prospective cohort study.

His Antibody research incorporates elements of Interleukin 3, Interleukin 20, Interleukin 5 and Interleukin 6. His Monoclonal antibody study combines topics in areas such as Molecular biology, Pharmacokinetics and In vitro. His studies in Rheumatoid arthritis integrate themes in fields like Connective tissue disease and Immunopathology.

Between 2006 and 2016, his most popular works were:

  • Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange (701 citations)
  • Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. (574 citations)
  • Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis (472 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Immune system

Lucien A. Aarden spends much of his time researching Immunology, Adalimumab, Rheumatoid arthritis, Internal medicine and Antibody. Monoclonal antibody and Immunogenicity are the primary areas of interest in his Immunology study. Lucien A. Aarden has researched Adalimumab in several fields, including Immunopathology and Arthritis.

His Rheumatoid arthritis research incorporates themes from Connective tissue disease and Infliximab. His biological study deals with issues like Gastroenterology, which deal with fields such as Surgery and Methotrexate. His Antibody research integrates issues from Proinflammatory cytokine, Immune system and Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Production of hybridoma growth factor by human monocytes.

Lucien A. Aarden;Els R. De Groot;Otto L. Schaap;Peter M. Lansdorp.
European Journal of Immunology (1987)

1387 Citations

Increased plasma levels of interleukin-6 in sepsis.

CE Hack;ER De Groot;RJ Felt-Bersma;JH Nuijens.
Blood (1989)

1176 Citations

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways

S. J. H. Van Deventer;H. R. Buller;J. W. Ten Cate;L. A. Aarden.
Blood (1990)

1126 Citations

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production.

T. C. T. M. Van Der Pouw Kraan;L. C. M. Boeije;R. J. T. Smeenk;J. Wijdenes.
Journal of Experimental Medicine (1995)

985 Citations

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten;Janine Schuurman;Mario Losen;Wim K. Bleeker.
Science (2007)

984 Citations

Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up.

Geertje M. Bartelds;Charlotte L. M. Krieckaert;Michael T. Nurmohamed;Pauline A. van Schouwenburg.
JAMA (2011)

839 Citations

IMMUNOLOGY OF DNA. III. CRITHIDIA LUCILIAE, A SIMPLE SUBSTRATE FOR THE DETERMINATION OF ANTI‐dsDNA WITH THE IMMUNOFLUORESCENCE TECHNIQUE*

L. A. Aarden;Els R. de Groot;T. E. W. Feltkamp.
Annals of the New York Academy of Sciences (1975)

784 Citations

Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis

Geertje M Bartelds;Carla A Wijbrandts;Michael T Nurmohamed;Steven Stapel.
Annals of the Rheumatic Diseases (2007)

681 Citations

Functional discrimination between interleukin 6 and interleukin 1

Maarten Helle;Leonie Boeije And and;Lucien A. Aarden.
European Journal of Immunology (1988)

640 Citations

Serum levels of interleukin-6 and acute phase responses.

M.W.N. Nijsten;E.R. De Groot;H.J. Ten Duis;H.J. Klasen.
The Lancet (1987)

616 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Lucien A. Aarden

Theo Rispens

Theo Rispens

University of Amsterdam

Publications: 91

Jan G. J. van de Winkel

Jan G. J. van de Winkel

Genmab (United States)

Publications: 61

Stefan Rose-John

Stefan Rose-John

Kiel University

Publications: 53

Andrej Tarkowski

Andrej Tarkowski

Sahlgrenska University Hospital

Publications: 47

Paul W. H. I. Parren

Paul W. H. I. Parren

Leiden University Medical Center

Publications: 46

Marcel Levi

Marcel Levi

University of Amsterdam

Publications: 46

Tom van der Poll

Tom van der Poll

University of Amsterdam

Publications: 45

Klaus Bendtzen

Klaus Bendtzen

University of Copenhagen

Publications: 42

Tadamitsu Kishimoto

Tadamitsu Kishimoto

Osaka University

Publications: 42

Catharina Svanborg

Catharina Svanborg

Lund University

Publications: 41

S. J. H. Van Deventer

S. J. H. Van Deventer

Leiden University

Publications: 39

Peter C. Heinrich

Peter C. Heinrich

University of Freiburg

Publications: 38

Cezmi A. Akdis

Cezmi A. Akdis

University of Zurich

Publications: 37

T. van der Poll

T. van der Poll

University of Amsterdam

Publications: 37

C. Erik Hack

C. Erik Hack

Utrecht University

Publications: 37

Frank Miedema

Frank Miedema

University of Amsterdam

Publications: 36

Trending Scientists

Hendrik Blockeel

Hendrik Blockeel

KU Leuven

Chunyan Miao

Chunyan Miao

Nanyang Technological University

Geert Ridder

Geert Ridder

University of Southern California

Hsiao-Wuen Hon

Hsiao-Wuen Hon

Microsoft Research Asia (China)

Karu P. Esselle

Karu P. Esselle

University of Technology Sydney

Daniel Lincot

Daniel Lincot

Centre national de la recherche scientifique, CNRS

Fengling Zhang

Fengling Zhang

Linköping University

Xiaoming Wen

Xiaoming Wen

Swinburne University of Technology

Kristofer M. Helgen

Kristofer M. Helgen

Australian Museum

Jun-ichi Nakayama

Jun-ichi Nakayama

National Institute for Basic Biology

Naweed I. Syed

Naweed I. Syed

University of Calgary

Michael Kneba

Michael Kneba

Kiel University

Robert F. Storey

Robert F. Storey

University of Sheffield

Alain Ravaud

Alain Ravaud

University of Bordeaux

Derrick A. Bennett

Derrick A. Bennett

University of Oxford

George Fein

George Fein

University of Hawaii System

Something went wrong. Please try again later.