D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 96 Citations 34,426 240 World Ranking 326 National Ranking 12
Medicine D-index 97 Citations 35,783 259 World Ranking 4324 National Ranking 129

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Virus
  • Antibody

Frank Miedema spends much of his time researching Immunology, Virology, T cell, CD8 and Cytotoxic T cell. As a member of one scientific family, Frank Miedema mostly works in the field of Immunology, focusing on Acquired immunodeficiency syndrome and, on occasion, Pathogenesis. His Virology research incorporates elements of Peripheral blood mononuclear cell and Asymptomatic.

The various areas that Frank Miedema examines in his T cell study include Molecular biology and Monoclonal antibody. His research investigates the connection between CD8 and topics such as Antiretroviral therapy that intersect with problems in Peripheral blood, Triple combination, Biphasic kinetics and Repopulation. His Cytotoxic T cell research focuses on subjects like Naive T cell, which are linked to Cell movement and Peripheral.

His most cited work include:

  • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. (981 citations)
  • HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. (868 citations)
  • Programmed death of T cells in HIV-1 infection (835 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Immunology, Virology, T cell, Cytotoxic T cell and CD8. Immunology and Acquired immunodeficiency syndrome are commonly linked in his work. His Antigen research extends to the thematically linked field of Virology.

His T cell research includes themes of Molecular biology, Antibody, Monoclonal antibody and CD3. His Cytotoxic T cell research is multidisciplinary, incorporating perspectives in Human leukocyte antigen and Epstein–Barr virus. His work carried out in the field of Virus brings together such families of science as Phenotype and Peripheral blood mononuclear cell.

He most often published in these fields:

  • Immunology (76.67%)
  • Virology (50.33%)
  • T cell (33.67%)

What were the highlights of his more recent work (between 2004-2015)?

  • Immunology (76.67%)
  • Virology (50.33%)
  • CD8 (26.00%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Virology, CD8, T cell and Immune system. Frank Miedema regularly links together related areas like Cytotoxic T cell in his Immunology studies. His Virology research is multidisciplinary, incorporating elements of Acquired immunodeficiency syndrome and Antigen.

The concepts of his CD8 study are interwoven with issues in Receptor and Thymic Tissue. His study explores the link between T cell and topics such as Whole blood that cross with problems in Cell cycle, Lymphocyte, Apoptosis and Mycophenolate. His Immune system study incorporates themes from HUMAN THYMUS, Antibody and CD38.

Between 2004 and 2015, his most popular works were:

  • Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool. (159 citations)
  • Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool. (159 citations)
  • CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater. (146 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Antibody
  • Virus

Frank Miedema focuses on Immunology, Immune system, T cell, CD8 and Virology. His Immunology research incorporates themes from Cytotoxic T cell, Internal medicine, Cohort and Antiretroviral therapy. Frank Miedema has included themes like Viral rebound, Viral load, Viral replication and Acquired immunodeficiency syndrome in his Internal medicine study.

The study incorporates disciplines such as Hematopoietic stem cell transplantation, Stem cell, Severe combined immunodeficiency and Immunopathology in addition to T cell. The CD8 study combines topics in areas such as Acquired immune system, Interferon and Senescence. He combines subjects such as Perforin, Granzyme and Granzyme B with his study of Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population.

H Schuitemaker;M Koot;N A Kootstra;M W Dercksen.
Journal of Virology (1992)

1539 Citations

Programmed death of T cells in HIV-1 infection

L Meyaard;SA Otto;RR Jonker;MJ Mijnster.
Science (1992)

1327 Citations

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors.

Stephen A. Migueles;Alisha C. Laborico;W. Lesley Shupert;M. Shirin Sabbaghian.
Nature Immunology (2002)

1146 Citations

Prognostic Value of HIV-1 Syncytium-Inducing Phenotype for Rate of CD4+ Cell Depletion and Progression to AIDS

Maarten Koot;Ireneus P. M. Keet;Aster H. V. Vos;Ruud E. Y. de Goede.
Annals of Internal Medicine (1993)

1094 Citations

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

Mette D. Hazenberg;Sigrid A. Otto;Birgit H. B. Van Benthem;Marijke Th. L. Roos.
AIDS (2003)

1016 Citations

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule.

R A Fouchier;M Groenink;N A Kootstra;M Tersmette.
Journal of Virology (1992)

956 Citations

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates.

M. Tersmette;R. A. Gruters;F. De Wolf;R. E. Y. De Goede.
Journal of Virology (1989)

872 Citations

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.

M Tersmette;R E de Goede;B J Al;I N Winkel.
Journal of Virology (1988)

853 Citations

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation

N. G. Pakker;D. W. Notermans;R. J. De Boer;M. T. L. Roos.
Nature Medicine (1998)

848 Citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

M R Klein;C A van Baalen;A M Holwerda;S R Kerkhof Garde.
Journal of Experimental Medicine (1995)

798 Citations

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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