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D-Index & Metrics

Immunology

D-Index
60
Citations
11685
World Ranking
3348
National Ranking
131

Overview

Michèl R. Klein is affiliated with Leiden University Medical Center in the Netherlands. Their research is situated primarily within the field of Medicine, with a particular focus on Infectious Diseases, Epidemiology, and Surgery.

Their work centers around several related topics including Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, Diagnosis and treatment of tuberculosis, and Infectious Diseases and Tuberculosis.

Klein has contributed to the following recent papers:

  • RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response (2020, Scientific Reports)
  • T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection (2023, Nature Medicine)

They have collaborated frequently with a core group of co-authors, including Nicole Bilek, Thomas J. Scriba, E. Jane Hughes, Ashley Veldsman, and Mzwandile Erasmus.

The main publication venues for Klein's work are Scientific Reports and Nature Medicine.

Best Publications

  • Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

    Dörte Hamann;Paul A. Baars;Martin H.G. Rep;Berend Hooibrink

  • Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

    M R Klein;C A van Baalen;A M Holwerda;S R Kerkhof Garde

  • MASS ACCUMULATION RATES IN ASIA DURING THE CENOZOIC

    François Métivier;Yves Gaudemer;Paul Tapponnier;Michel Klein

  • Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

    Eliane M.S. Leyten;May Young Lin;Kees L.M.C. Franken;Annemieke H. Friggen

  • Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

    Jaap T. van Dissel;Sandra M. Arend;Corine Prins;Peter Bang

  • Recognition of Stage-Specific Mycobacterial Antigens Differentiates between Acute and Latent Infections with Mycobacterium tuberculosis

    Abebech Demissie;Eliane M. S. Leyten;Markos Abebe;Liya Wassie

  • Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inversely correlate with rapid progression to AIDS

    C.A. van Baalen;O. Pontesilli;R.C. Huisman;A.M. Geretti

  • High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: evidence for impaired CTL effector function.

    S Kostense;G S Ogg;E H Manting;G Gillespie

  • Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4.

    Simone A. Joosten;Krista E. van Meijgaarden;Nigel D. L. Savage;Tjitske de Boer

  • Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice

    Virginie Roupie;Marta Romano;Lei Zhang;Hannelie Korf

  • Longitudinal Phenotypic Analysis of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes: Correlation with Disease Progression

    Graham S. Ogg;Stefan Kostense;Michel R. Klein;Suzanne Jurriaans

  • Changing virus-host interactions in the course of HIV-1 infection.

    Frank Miedema;Linde Meyaard;Maarten Koot;Michel Klein

  • Protection against respiratory syncytial virus infection by DNA immunization.

    Xiaomao Li;Suryaprakash Sambhara;Cindy Xin Li;Mary Ewasyshyn

  • Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8+ T-cells with cytotoxic as well as regulatory activity.

    Simone A. Joosten;Krista E. van Meijgaarden;Pascale C. van Weeren;Fatima Kazi

  • Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.

    Gillian F. Black;Bonnie A. Thiel;Martin O. Ota;Shreemanta K. Parida

  • Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients.

    Norbert A. Foudraine;Egbert Hovenkamp;Daan W. Notermans;Pieter L. Meenhorst

  • Human CD8+ CTL Specific for the Mycobacterial Major Secreted Antigen 85A

    Steven M. Smith;Roger Brookes;Michèl R. Klein;Adam S. Malin

  • Review of enterovirus 71 vaccines

    Pele Chong;Chia-Chyi Liu;Yen-Hung Chow;Yen-Hung Chow;Ai-Hsiang Chou

  • Expression of biological effector functions by immunoglobulin G molecules lacking the hinge region.

    Michel Klein;Nicole Haeffner-Cavaillon;David E. Isenman;Claude Rivat

  • Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.

    M. R. Klein;S. H. Van Der Burg;E. Hovenkamp;A. M. Holwerda

Frequent Co-Authors

Frank Miedema
Frank Miedema Utrecht University
Tom H. M. Ottenhoff
Tom H. M. Ottenhoff Leiden University Medical Center
Kees L. M. C. Franken
Kees L. M. C. Franken Leiden University Medical Center
Krista E. van Meijgaarden
Krista E. van Meijgaarden Leiden University Medical Center
F. de Wolf
F. de Wolf Imperial College London
Annemieke Geluk
Annemieke Geluk Leiden University Medical Center
Suryaprakash Sambhara
Suryaprakash Sambhara Centers for Disease Control and Prevention
Hazel M. Dockrell
Hazel M. Dockrell London School of Hygiene & Tropical Medicine
Anna Maria Geretti
Anna Maria Geretti University of Liverpool
Nicole Haeffner-Cavaillon
Nicole Haeffner-Cavaillon Inserm : Institut national de la santé et de la recherche médicale

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Related Online Degrees & Career Pathways

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Combining immunology with these nursing tracks can lead to impactful careers in clinical research, public health, and specialized nursing roles focused on immunotherapies and infectious diseases.

Best Scientists Citing Michèl R. Klein

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