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Krista E. van Meijgaarden

Krista E. van Meijgaarden

D-Index & Metrics

Immunology

D-Index
48
Citations
8257
World Ranking
4439
National Ranking
175

Overview

Krista E. van Meijgaarden is affiliated with Leiden University Medical Center in the Netherlands and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their work focuses largely on immunological responses, infectious diseases, and host-pathogen interactions, with a particular emphasis on tuberculosis and immune system dynamics.

The main research topics addressed in their publications include:

  • Tuberculosis Research and Epidemiology
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Mycobacterium research and diagnosis
  • Immune responses and vaccinations
  • SARS-CoV-2 and COVID-19 Research

Their frequent publication venues encompass:

  • iScience
  • Scientific Reports
  • Frontiers in Immunology
  • The Journal of Immunology
  • European Journal of Pharmaceutical Sciences

Krista E. van Meijgaarden's collaborations involve several recurrent coauthors including:

  • Tom H. M. Ottenhoff
  • Simone A. Joosten
  • Kees L. M. C. Franken
  • Annemieke Geluk
  • Thomas J. Scriba

Their published works include several notable papers, such as:

  • "RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response" (2020) in Scientific Reports
  • "T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection" (2023) in Nature Medicine
  • "A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity" (2023) in Cell Reports
  • "Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups" (2020) in Frontiers in Immunology
  • "Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults" (2022) in Frontiers in Immunology

Within the subfields of study, their contributions primarily relate to:

  • Immunology
  • Infectious Diseases
  • Molecular Biology
  • Epidemiology
  • Surgery

Best Publications

  • Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

    Eliane M.S. Leyten;May Young Lin;Kees L.M.C. Franken;Annemieke H. Friggen

  • Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvent.

    Kees L.M.C. Franken;Hoebert S. Hiemstra;Krista E. van Meijgaarden;Yanri Subronto

  • Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

    Nigel D. L. Savage;Tjitske de Boer;Kimberley V. Walburg;Simone A. Joosten

  • Detection of Active Tuberculosis Infection by T Cell Responses to Early-Secreted Antigenic Target 6-kDa Protein and Culture Filtrate Protein 10

    Sandra M. Arend;Peter Andersen;Krista E. van Meijgaarden;Rikke L. V. Skjøt

  • Antigenic Equivalence of Human T-Cell Responses to Mycobacterium tuberculosis-Specific RD1-Encoded Protein Antigens ESAT-6 and Culture Filtrate Protein 10 and to Mixtures of Synthetic Peptides

    Sandra M. Arend;Annemieke Geluk;Krista E. van Meijgaarden;Jaap T. van Dissel

  • Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10

    Delphine Rea;Cees van Kooten;Krista E. van Meijgaarden;Tom H. M. Ottenhoff

  • Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis.

    Maytal Bivas-Benita;Krista E. van Meijgaarden;Kees L.M.C. Franken;Hans E. Junginger

  • Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4.

    Simone A. Joosten;Krista E. van Meijgaarden;Nigel D. L. Savage;Tjitske de Boer

  • Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes.

    Sjoerd H. van der Burg;Maaike E. Ressing;Kitty M.C. Kwappenberg;Annemieke de Jong

  • Tuberculin Skin Testing and In Vitro T Cell Responses to ESAT-6 and Culture Filtrate Protein 10 after Infection with Mycobacterium marinum or M. kansasii

    Sandra M. Arend;Krista E. van Meijgaarden;Kirsten de Boer;Elisabeth Cerdá de Palou

  • Identification of Major Epitopes of Mycobacterium tuberculosis AG85B That Are Recognized by HLA-A*0201-Restricted CD8+ T Cells in HLA-Transgenic Mice and Humans

    A. Geluk;K. E. van Meijgaarden;K. L. M. C. Franken;J. W. Drijfhout

  • Mycobacterial growth inhibition is associated with trained innate immunity

    Simone A. Joosten;Krista E. van Meijgaarden;Sandra M. Arend;Corine Prins

  • Frequent Detection of Human Papillomavirus 16 E2-specific T-helper Immunity in Healthy Subjects

    Annemieke de Jong;Sjoerd H. van der Burg;Kitty M. C. Kwappenberg;Jeanette M. van der Hulst

  • Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8+ T-cells with cytotoxic as well as regulatory activity.

    Simone A. Joosten;Krista E. van Meijgaarden;Pascale C. van Weeren;Fatima Kazi

  • Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

    Simone A. Joosten;Krista E. van Meijgaarden;Franca del Nonno;Andrea Baiocchini

  • Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.

    Annemieke Geluk;Krista E. van Meijgaarden;Kees L. M. C. Franken;Yanri W. Subronto

  • RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

    Adam Penn-Nicholson;Stanley Kimbung Mbandi;Ethan Thompson;Simon C Mendelsohn

  • Metabolite changes in blood predict the onset of tuberculosis

    January rd Weiner;Jeroen Maertzdorf;Jayne S. Sutherland;Fergal J. Duffy

  • Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice.

    Maytal Bivas-Benita;May Young Lin;Suzanne M. Bal;Krista E. van Meijgaarden

  • Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity

    Simone A Joosten;Krista E van Meijgaarden;Pascale C van Weeren;Fatima Kazi

  • T-Cell Recognition of the HspX Protein of Mycobacterium tuberculosis Correlates with Latent M. tuberculosis Infection but Not with M. bovis BCG Vaccination

    Annemieke Geluk;May Young Lin;Krista E. van Meijgaarden;Eliane M. S. Leyten

Frequent Co-Authors

Tom H. M. Ottenhoff
Tom H. M. Ottenhoff Leiden University Medical Center
Annemieke Geluk
Annemieke Geluk Leiden University Medical Center
Kees L. M. C. Franken
Kees L. M. C. Franken Leiden University Medical Center
Simone A. Joosten
Simone A. Joosten Leiden University Medical Center
Michèl R. Klein
Michèl R. Klein Leiden University Medical Center
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Francesco Dieli
Francesco Dieli University of Palermo
Jaap T. van Dissel
Jaap T. van Dissel Leiden University Medical Center
Hazel M. Dockrell
Hazel M. Dockrell London School of Hygiene & Tropical Medicine
Gary K. Schoolnik
Gary K. Schoolnik Stanford University

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