World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
68
Citations
11689
World Ranking
2633
National Ranking
102

Kees L. M. C. Franken publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Kees L. M. C. Franken sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 159 publications — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Kees L. M. C. Franken D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Kees L. M. C. Franken sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 68 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Kees L. M. C. Franken is affiliated with Leiden University Medical Center in the Netherlands. Their research spans several fields within medicine, focusing notably on immunology and microbiology.

Their work encompasses various subfields including immunology, infectious diseases, epidemiology, oncology, and molecular biology. The main topics they have contributed to include tuberculosis research and epidemiology, immune cell function and interaction, immunotherapy and immune responses, T-cell and B-cell immunology, Mycobacterium research and diagnosis, vaccines and immunoinformatics approaches, as well as cancer immunotherapy and biomarkers.

Frequent publication venues for their research include:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • npj Vaccines
  • SSRN Electronic Journal

Some of their recent papers are listed below:

  • "RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response" (2020) published in Scientific Reports
  • "T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection" (2023) published in Nature Medicine
  • "A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection" (2022) published in Nature Communications
  • "IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors" (2021) published in Journal for ImmunoTherapy of Cancer
  • "Cell-Mediated Immune Responses to in vivo-Expressed and Stage-Specific Mycobacterium tuberculosis Antigens in Latent and Active Tuberculosis Across Different Age Groups" (2020) published in Frontiers in Immunology

Their frequent co-authors include:

  • Tom H. M. Ottenhoff (27 collaborations)
  • Simone A. Joosten (14 collaborations)
  • Krista E. van Meijgaarden (13 collaborations)
  • Annemieke Geluk (10 collaborations)
  • Thomas J. Scriba (8 collaborations)

Kees L. M. C. Franken's work covers a significant volume of publications, with 63 contributions classified under Medicine and 57 under Immunology and Microbiology. Their research contributions focus substantially on immune mechanisms related to infectious diseases such as tuberculosis, as well as on immune responses in oncology and vaccine development.

Best Publications

  • Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

    J. P. Medema;J. de Jong;L. T. C. Peltenburg;E. M. E. Verdegaal

  • CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund’s Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity

    Martijn S. Bijker;Susan J. F. van den Eeden;Kees L. Franken;Cornelis J. M. Melief

  • Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

    Eliane M.S. Leyten;May Young Lin;Kees L.M.C. Franken;Annemieke H. Friggen

  • Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvent.

    Kees L.M.C. Franken;Hoebert S. Hiemstra;Krista E. van Meijgaarden;Yanri Subronto

  • Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses

    Marij J. P. Welters;Gemma G. Kenter;Peggy J. de Vos van Steenwijk;Margriet J. G. Löwik

  • Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter.

    Marij J. P. Welters;Annemieke de Jong;Susan J. F. van den Eeden;Jeanette M. van der Hulst

  • Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

    Martijn S. Bijker;Susan J. F. van den Eeden;Kees L. Franken;Cornelis J. M. Melief

  • Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation.

    Rodney A. Rosalia;Esther D. Quakkelaar;Anke Redeker;Selina Khan

  • Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

    Hoebert S. Hiemstra;Nanette C. Schloot;Peter A. van Veelen;Sabine J. M. Willemen

  • Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis.

    Maytal Bivas-Benita;Krista E. van Meijgaarden;Kees L.M.C. Franken;Hans E. Junginger

  • Natural T-helper immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: identification of 3 human leukocyte antigen class II-restricted epitopes.

    Sjoerd H. van der Burg;Maaike E. Ressing;Kitty M.C. Kwappenberg;Annemieke de Jong

  • Simultaneous Detection of Circulating Autoreactive CD8 + T-Cells Specific for Different Islet Cell–Associated Epitopes Using Combinatorial MHC Multimers

    Jurjen H. Velthuis;Wendy W. Unger;Joana R.F. Abreu;Gaby Duinkerken;Gaby Duinkerken

  • Identification of Major Epitopes of Mycobacterium tuberculosis AG85B That Are Recognized by HLA-A*0201-Restricted CD8+ T Cells in HLA-Transgenic Mice and Humans

    A. Geluk;K. E. van Meijgaarden;K. L. M. C. Franken;J. W. Drijfhout

  • Frequent Detection of Human Papillomavirus 16 E2-specific T-helper Immunity in Healthy Subjects

    Annemieke de Jong;Sjoerd H. van der Burg;Kitty M. C. Kwappenberg;Jeanette M. van der Hulst

  • Immunization with Human Papillomavirus Type 16 (HPV16) Oncoprotein-loaded Dendritic Cells as well as Protein in Adjuvant Induces MHC Class I-restricted Protection to HPV16-induced Tumor Cells

    M. L. H. De Bruijn;D. H. Schuurhuis;M. P. M. Vierboom;H. Vermeulen

  • Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis

    Ann Williams;Graham J. Hatch;Simon O. Clark;Karen E. Gooch

  • Immunogenicity of Eight Dormancy Regulon-Encoded Proteins of Mycobacterium tuberculosis in DNA-Vaccinated and Tuberculosis-Infected Mice

    Virginie Roupie;Marta Romano;Lei Zhang;Hannelie Korf

  • Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants

    Thorbald van Hall;Elisabeth Z Wolpert;Peter van Veelen;Sandra Laban

  • Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.

    Gillian F. Black;Bonnie A. Thiel;Martin O. Ota;Shreemanta K. Parida

  • Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.

    Annemieke Geluk;Krista E. van Meijgaarden;Kees L. M. C. Franken;Yanri W. Subronto

Frequent Co-Authors

Tom H. M. Ottenhoff
Tom H. M. Ottenhoff Leiden University Medical Center
Annemieke Geluk
Annemieke Geluk Leiden University Medical Center
Cornelis J. M. Melief
Cornelis J. M. Melief ISA Pharmaceuticals (Netherlands)
Krista E. van Meijgaarden
Krista E. van Meijgaarden Leiden University Medical Center
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Sjoerd H. van der Burg
Sjoerd H. van der Burg Leiden University Medical Center
Rienk Offringa
Rienk Offringa German Cancer Research Center
Michèl R. Klein
Michèl R. Klein Leiden University Medical Center
Ferry Ossendorp
Ferry Ossendorp Leiden University Medical Center
Abraham Aseffa
Abraham Aseffa Armauer Hansen Research Institute

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