His primary areas of investigation include Immunology, Autoimmunity, T cell, Type 1 diabetes and Immune system. His Immunology study often links to related topics such as Islet. Mark Peakman combines subjects such as Autoimmune disease and Innate immune system with his study of Autoimmunity.
His studies deal with areas such as Acquired immune system, CD8, Microbiology, Human leukocyte antigen and Major histocompatibility complex as well as T cell. His study looks at the relationship between CD8 and fields such as T-cell receptor, as well as how they intersect with chemical problems. Mark Peakman works mostly in the field of Type 1 diabetes, limiting it down to concerns involving Immunotherapy and, occasionally, Proinsulin, Cytotoxic T cell and Antigen specific.
Mark Peakman spends much of his time researching Immunology, Type 1 diabetes, Immune system, T cell and Diabetes mellitus. In his study, which falls under the umbrella issue of Immunology, Transplantation is strongly linked to Islet. The study incorporates disciplines such as Clinical trial, Bioinformatics, Proinsulin, Intensive care medicine and Disease in addition to Type 1 diabetes.
His T cell research is multidisciplinary, incorporating perspectives in MHC class I, CD8, Major histocompatibility complex and Cell biology. His studies in CD8 integrate themes in fields like Cytotoxic T cell, IL-2 receptor and T lymphocyte. The Diabetes mellitus study combines topics in areas such as Autoantibody and Internal medicine.
The scientist’s investigation covers issues in Type 1 diabetes, Immunology, T cell, Autoimmunity and Immune system. His Type 1 diabetes research incorporates themes from Intensive care medicine, Internal medicine, Disease and Immunotherapy. The concepts of his Immunology study are interwoven with issues in Phenotype, Cytotoxic T cell and Islet.
His T cell study combines topics from a wide range of disciplines, such as Epitope, Computational biology, Major histocompatibility complex and Abatacept. His study focuses on the intersection of Autoimmunity and fields such as Vaccination with connections in the field of Glutamate decarboxylase and Adverse effect. Immune system and Human leukocyte antigen are frequently intertwined in his study.
Type 1 diabetes, Disease, Immunology, Autoimmunity and T cell are his primary areas of study. Mark Peakman combines subjects such as Cytotoxic T cell, Immune tolerance and Immunotherapy with his study of Type 1 diabetes. He interconnects Precision medicine, Clinical trial, Myeloid, Immune system and Intensive care medicine in the investigation of issues within Disease.
His Immunology study integrates concerns from other disciplines, such as Phenotype and Young adult. His study in Autoimmunity is interdisciplinary in nature, drawing from both Acquired immune system, Autoimmune disease, Adverse effect, Influenza A virus and Vaccination. His studies deal with areas such as Staining and Antigen as well as T cell.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes
Shelley Lindley;Colin M. Dayan;Amanda Bishop;Bart O. Roep.
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health
Sefina Arif;Timothy I. Tree;Thomas P. Astill;Jennifer M. Tremble.
Journal of Clinical Investigation (2004)
CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope
Ania Skowera;Richard J. Ellis;Ruben Varela-Calviño;Sefina Arif.
Journal of Clinical Investigation (2008)
A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides
Linda Wooldridge;Julia Ekeruche-Makinde;Hugo A. van den Berg;Anna Skowera;Anna Skowera.
Journal of Biological Chemistry (2012)
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM
M. J. Hussain;M. Peakman;H. Gallati;S. S. S. Lo.
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.
T. P. Di Lorenzo;M. Peakman;B. O. Roep.
Clinical and Experimental Immunology (2007)
Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation
Chung-Ching Chu;Niwa Ali;Panagiotis Karagiannis;Paola Di Meglio.
Journal of Experimental Medicine (2012)
Antigen Targets of Type 1 Diabetes Autoimmunity
Bart O Roep;Mark Peakman.
Cold Spring Harbor Perspectives in Medicine (2012)
Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Sefina Arif;Fabrice Moore;Katherine Marks;Thomas Bouckenooghe.
Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function
Garima Garg;Jennifer R Tyler;Jennie H M Yang;Antony J Cutler.
Journal of Immunology (2012)
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