John J. Miles spends much of his time researching T-cell receptor, Antigen, Immunology, T cell and Major histocompatibility complex. In most of his Antigen studies, his work intersects topics such as Receptor. His Immune system, Vaccination and Adjuvant study in the realm of Immunology interacts with subjects such as Repertoire.
Mucosal associated invariant T cell is the focus of his T cell research. His work carried out in the field of Major histocompatibility complex brings together such families of science as CD8 and Cell biology. His CD8 research focuses on Epitope and how it relates to Human leukocyte antigen, Molecular biology, Mononucleosis, Seroconversion and Tetanus.
John J. Miles mostly deals with T-cell receptor, T cell, Immunology, Antigen and Major histocompatibility complex. His T-cell receptor study combines topics in areas such as Molecular biology, Human leukocyte antigen, CD8 and Cell biology. His T cell research includes elements of MHC class I, Gene and Stem cell.
The Antigen study combines topics in areas such as Receptor and Computational biology. His studies in Major histocompatibility complex integrate themes in fields like T-Cell Antigen Receptor Specificity, Acquired immune system and Plasma protein binding. His Epitope research focuses on subjects like Virology, which are linked to Mutation.
The scientist’s investigation covers issues in Immune system, Cancer research, T-cell receptor, T cell and Immunology. His research in Immune system intersects with topics in Epitope, Antigen, Ex vivo and Cytokine. His T-cell receptor research is multidisciplinary, incorporating elements of Receptor, Ligand, Cell biology, Computational biology and Major histocompatibility complex.
The concepts of his Major histocompatibility complex study are interwoven with issues in Amino acid and Peptide. His study in T cell is interdisciplinary in nature, drawing from both UniProt, Proteomics, Quantitative proteomics, Genomics and PeptideAtlas. His research integrates issues of Phenotype, Hypoestrogenism and Pectus excavatum in his study of Immunology.
His primary areas of study are Cancer research, Cell cycle, Major histocompatibility complex, Immune system and Programmed cell death. His Cancer research research includes themes of Foreskin, Infectious disease, Immune checkpoint, Phenotype and CD8. John J. Miles has researched Major histocompatibility complex in several fields, including Epitope, T cell and Influenza A virus.
John J. Miles combines subjects such as Priming, Autologous transplantation, Multiple myeloma and Immunotherapy with his study of T cell. The study incorporates disciplines such as Ex vivo, Colitis, Inflammatory bowel disease, Ancylostoma caninum and Ancylostoma in addition to Immune system. The various areas that John J. Miles examines in his Antigen study include Receptor, Cell biology, Antigen presentation and T-cell receptor.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko.
Nature (2012)
T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules
Jamie Rossjohn;Stephanie Gras;John James Miles;Stephen J. Turner.
Annual Review of Immunology (2015)
A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides
Linda Wooldridge;Julia Ekeruche-Makinde;Hugo A. van den Berg;Anna Skowera;Anna Skowera.
Journal of Biological Chemistry (2012)
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.
Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements.
Nature Immunology (2005)
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Fleur Elizabeth Tynan;Hugh Harrington Reid;Lars Kjer-Nielsen;John J Miles.
Nature Immunology (2007)
Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination.
John James Miles;John James Miles;Daniel C. Douek;David Price;David Price.
Immunology and Cell Biology (2011)
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Onisha Patel;Lars Kjer-Nielsen;Jérôme Le Nours;Jérôme Le Nours;Sidonia B G Eckle.
Nature Communications (2013)
IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling
Shuo Li;Marie-Paule Lefranc;John J. Miles;John J. Miles;John J. Miles;Eltaf Alamyar.
Nature Communications (2013)
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Anna Marta Bulek;David Cole;Ania Skowera;Ania Skowera;Garry Michael Dolton.
Nature Immunology (2012)
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.
Natalie A Borg;Lauren Kate Ely;Travis Clarke Beddoe;Whitney Alison Macdonald.
Nature Immunology (2005)
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