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Anthony W. Purcell

Anthony W. Purcell

D-Index & Metrics

Immunology

D-Index
86
Citations
29149
World Ranking
1252
National Ranking
43

Overview

Anthony W. Purcell is affiliated with Monash University in Australia and has contributed extensively to the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their research spans core areas including Immunology, Molecular Biology, and Oncology, with additional work in Radiology, Nuclear Medicine and Imaging, and Epidemiology.

The scientist's research interests encompass several prominent topics such as vaccines and immunoinformatics approaches, immunotherapy and immune responses, T-cell and B-cell immunology, immune cell function and interaction, monoclonal and polyclonal antibodies research, peptidase inhibition and analysis, and CAR-T cell therapy research.

Recent publications by Anthony W. Purcell include:

  • "Transcriptional signature in microglia associated with Aβ plaque phagocytosis," 2021, Nature Communications
  • "Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system," 2020, PLoS Computational Biology
  • "A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice," 2020, Cell Host & Microbe
  • "ggVolcanoR: A Shiny app for customizable visualization of differential expression datasets," 2021, Computational and Structural Biotechnology Journal
  • "PCprophet: a framework for protein complex prediction and differential analysis using proteomic data," 2021, Nature Methods

Frequent co-authors collaborating with Purcell include:

  • Patricia T. Illing (35 joint publications)
  • Pouya Faridi (35 joint publications)
  • Nicole A. Mifsud (31 joint publications)
  • Sri H. Ramarathinam (31 joint publications)
  • Ruedi Aebersold (25 joint publications)

The researcher has published frequently in scientific venues such as:

  • PROTEOMICS (25 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (16 publications)
  • Frontiers in Immunology (9 publications)
  • Nature Communications (6 publications)
  • Molecular & Cellular Proteomics (6 publications)

Best Publications

  • MR1 presents microbial vitamin B metabolites to MAIT cells

    Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours

  • Linear ubiquitination prevents inflammation and regulates immune signalling

    Bjã¶rn Gerlach;Stefanie M. Cordier;Anna C. Schmukle;Christoph H. Emmerich;Christoph H. Emmerich

  • More than one reason to rethink the use of peptides in vaccine design

    Anthony W. Purcell;James McCluskey;Jamie Rossjohn

  • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

    Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko

  • Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

    Annalise M. Martin;David Nolan;Silvana Gaudieri;Silvana Gaudieri;Coral Ann Almeida

  • A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

    Stephen Scally;Jan Petersen;Soi Cheng Cheng Law;Nadine Lee Dudek

  • Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin

    Anthony P Williams;Chen Au Peh;Anthony W Purcell;James McCluskey

  • A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

    Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks

  • Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients.

    Helen Benham;Helen Benham;Hendrik J. Nel;Soi Cheng Law;Ahmed M. Mehdi

  • Transcriptional signature in microglia associated with Aβ plaque phagocytosis.

    Alexandra Grubman;Alexandra Grubman;Alexandra Grubman;Xin Yi Choo;Gabriel Chew;John F Ouyang

  • Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

    Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell

  • Mass spectrometry-based identification of MHC-bound peptides for immunopeptidomics.

    Anthony W. Purcell;Sri H. Ramarathinam;Nicola Ternette

  • T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

    Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements

  • T Cell Allorecognition via Molecular Mimicry

    Whitney Alison Macdonald;Zhenjun Chen;Stephanie Gras;Julia Kate Archbold

  • A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

    Fleur Elizabeth Tynan;Hugh Harrington Reid;Lars Kjer-Nielsen;John J Miles

  • Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

    Balasubramanian Krishnamurthy;Nadine L. Dudek;Mark D. McKenzie;Anthony W. Purcell

  • The insulin A-chain epitope recognized by human T cells is posttranslationally modified.

    Stuart I. Mannering;Leonard C. Harrison;Nicholas A. Williamson;Jessica S. Morris

  • Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

    Andrew N Keller;Sidonia B G Eckle;Weijun Xu;Ligong Liu

  • Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

    Marios Koutsakos;Patricia T. Illing;Thi H. O. Nguyen;Nicole A. Mifsud

  • A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

    Kate Henderson;Jason A Tye-Din;Jason A Tye-Din;Hugh Harrington Reid;Zhenjun Chen

  • Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

    Joshua D Ooi;Jan Petersen;Jan Petersen;Yu H Tan;Megan Huynh

  • A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

    Whitney A Macdonald;Anthony W Purcell;Nicole A Mifsud;Lauren Kate Ely

  • The Structure of H-2Kb and Kbm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance

    Andrew Ian Webb;Natalie A Borg;Michelle Anne Dunstone;Lars Kjer-Nielsen

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
James McCluskey
James McCluskey University of Melbourne
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Stephanie Gras
Stephanie Gras La Trobe University
Kurt Lambeck
Kurt Lambeck Australian National University
Scott R. Burrows
Scott R. Burrows QIMR Berghofer Medical Research Institute
John J. Miles
John J. Miles James Cook University
Travis Clarke Beddoe
Travis Clarke Beddoe La Trobe University
Andrew G. Brooks
Andrew G. Brooks University of Melbourne
Zhenjun Chen
Zhenjun Chen University of Melbourne

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