World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
42
Citations
10509
World Ranking
4874
National Ranking
214

Overview

Zhenjun Chen is affiliated with the University of Melbourne in Australia and conducts research primarily in the fields of immunology and microbiology, with additional work in medicine. Their research spans subfields including immunology, epidemiology, electrical and electronic engineering, molecular biology, and infectious diseases.

The scientist's work centers on several main topics: immune cell function and interaction, T-cell and B-cell immunology, cytomegalovirus and herpesvirus research, immunotherapy and immune responses, CAR-T cell therapy research, phagocytosis and immune regulation, and RNA modifications and cancer.

Frequent publication venues for Chen include:

  • Frontiers in Immunology
  • Nature Communications
  • Mucosal Immunology
  • The Journal of Experimental Medicine
  • Nature Immunology

Chen has collaborated regularly with researchers such as James McCluskey, Alexandra J. Corbett, Huimeng Wang, Sidonia B. G. Eckle, and Adam G. Nelson.

Some of the recent papers authored by or related to Chen's research include:

  • "Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection," 2021, Nature Communications
  • "IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia," 2020, Mucosal Immunology
  • "Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection," 2021, Nature Communications
  • "CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells," 2022, The Journal of Experimental Medicine
  • "Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries," 2020, Frontiers in Immunology

Best Publications

  • MR1 presents microbial vitamin B metabolites to MAIT cells

    Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways

    Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu

  • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

    Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko

  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

    Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin

  • Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

    Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell

  • Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant t cells using MR1 tetramers

    Azad Rahimpour;Hui Fern Koay;Anselm Enders;Rhiannon Clanchy

  • A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

    Hui-Fern Koay;Nicholas A Gherardin;Nicholas A Gherardin;Anselm Enders;Liyen Loh

  • A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

    Sidonia B G Eckle;Richard W Birkinshaw;Lyudmila Kostenko;Alexandra J Corbett

  • Recognition of vitamin B metabolites by mucosal-associated invariant T cells.

    Onisha Patel;Lars Kjer-Nielsen;Jérôme Le Nours;Jérôme Le Nours;Sidonia B. G. Eckle

  • T Cell Allorecognition via Molecular Mimicry

    Whitney Alison Macdonald;Zhenjun Chen;Stephanie Gras;Julia Kate Archbold

  • Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

    Z. Chen;H. Wang;C. D'Souza;S. Sun

  • Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

    Andrew N Keller;Sidonia B G Eckle;Weijun Xu;Ligong Liu

  • A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

    Kate Henderson;Jason A Tye-Din;Jason A Tye-Din;Hugh Harrington Reid;Zhenjun Chen

  • MAIT cells protect against pulmonary Legionella longbeachae infection.

    Huimeng Wang;Criselle D’Souza;Xin Yi Lim;Lyudmila Kostenko

  • Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

    Rangsima Reantragoon;Lars Kjer-Nielsen;Onisha G Patel;Zhenjun Chen

  • Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

    Timothy S.C. Hinks;Timothy S.C. Hinks;Emanuele Marchi;Maisha Jabeen;Moshe Olshansky;Moshe Olshansky

  • The intracellular pathway for the presentation of vitamin B–related antigens by the antigen-presenting molecule MR1

    Hamish E G McWilliam;Sidonia B G Eckle;Alex Theodossis;Ligong Liu

  • MAIT cells contribute to protection against lethal influenza infection in vivo

    Bonnie van Wilgenburg;Bonnie van Wilgenburg;Liyen Loh;Zhenjun Chen;Troi J. Pediongco

  • Molecular architecture of the αβ T cell receptor–CD3 complex

    Michael E Birnbaum;Richard Berry;Yu-Shan Stephanie Hsiao;Zhenjun Chen

  • Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

    Jeffrey Y. W. Mak;Weijun Xu;Robert C. Reid;Alexandra J. Corbett

  • T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

    Dennis X. Beringer;Fleur S. Kleijwegt;Florian Wiede;Arno R. Van Der Slik

  • Antigen Ligation Triggers a Conformational Change within the Constant Domain of the αβ T Cell Receptor

    Travis Clarke Beddoe;Zhenjun Chen;Craig Steven Clements;Lauren Kate Ely

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
James McCluskey
James McCluskey University of Melbourne
David P. Fairlie
David P. Fairlie University of Queensland
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Anthony W. Purcell
Anthony W. Purcell Monash University
Scott R. Burrows
Scott R. Burrows QIMR Berghofer Medical Research Institute
Richard A. Strugnell
Richard A. Strugnell University of Melbourne
Stephanie Gras
Stephanie Gras La Trobe University
John J. Miles
John J. Miles James Cook University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, several related healthcare degrees can complement or expand career opportunities. Many students explore nursing programs as a pathway to clinical roles that intersect with immunological research and patient care. If you’re looking for accessible entry points, there are options like easiest accelerated nursing programs that allow fast-tracked education paired with practical experience.

Licensed Practical Nurse (LPN) programs often provide a foundational healthcare education, and you can find lpn schools easy to get into which can help begin a career focused on direct patient care. Building on the LPN foundation, pursuing a Registered Nurse (RN) or Nurse Practitioner degree can lead to specialized roles.

Specifically, some students aim for advanced practice nursing by choosing the which nurse practitioner program is easiest to balance rigorous coursework with hands-on training. For those drawn to mental health and immunology’s role in neuroimmunology, top psychiatric mental health nurse practitioner programs online provide flexible options with strong clinical placement support.

Choosing the right online degree or pathway involves evaluating program difficulty, clinical opportunities, and your career goals. These options offer varied routes into immunology-related healthcare careers with adaptable schedules and accessible admission standards.

Best Scientists Citing Zhenjun Chen

Trending Scientists