Lars Kjer-Nielsen spends much of his time researching Antigen, T-cell receptor, T cell, Major histocompatibility complex and Antigen presentation. In his research on the topic of Antigen, Biochemistry is strongly related with Immune system. His work carried out in the field of T-cell receptor brings together such families of science as Molecular biology and Cell biology.
Lars Kjer-Nielsen studies T cell, focusing on Mucosal associated invariant T cell in particular. His Major histocompatibility complex study is concerned with Immunology in general. His studies in Antigen presentation integrate themes in fields like HLA-B Antigens, Human leukocyte antigen and MHC class I.
Lars Kjer-Nielsen mainly investigates T-cell receptor, T cell, Major histocompatibility complex, Antigen and Cell biology. His T-cell receptor research is multidisciplinary, relying on both Epitope, Molecular biology and Antigen presentation. Lars Kjer-Nielsen works mostly in the field of T cell, limiting it down to topics relating to Human leukocyte antigen and, in certain cases, Peptide.
In the field of Major histocompatibility complex, his study on MHC class I and MHC restriction overlaps with subjects such as Population. His Antigen study combines topics in areas such as Receptor, Biochemistry, Mucosal associated invariant T cell and Virology. The various areas that Lars Kjer-Nielsen examines in his Cell biology study include Protein structure and Transfection.
T-cell receptor, Mucosal associated invariant T cell, Antigen, Immunology and T cell are his primary areas of study. His T-cell receptor study combines topics from a wide range of disciplines, such as MHC class I, CD8, Major histocompatibility complex and Cell biology. Within one scientific family, he focuses on topics pertaining to Antigen presentation under Major histocompatibility complex, and may sometimes address concerns connected to CD1.
His Antigen research is multidisciplinary, incorporating elements of Molecular biology and Interleukin 12. His work deals with themes such as Peripheral, Receptor and Treatment response, which intersect with Immunology. T cell is a primary field of his research addressed under Immune system.
His primary areas of study are Mucosal associated invariant T cell, T-cell receptor, Antigen, T cell and Major histocompatibility complex. His research integrates issues of Cell activation and Interleukin 17 in his study of Mucosal associated invariant T cell. His study on T-cell receptor is covered under Immune system.
His T cell study is concerned with the field of Immunology as a whole. He interconnects Plasma protein binding, Cell biology and Antigen presentation in the investigation of issues within Major histocompatibility complex. His CD8 research is multidisciplinary, incorporating perspectives in Cytotoxic T cell, Epstein–Barr virus, Immunopathology and Virology.
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MR1 presents microbial vitamin B metabolites to MAIT cells
Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours.
Nature (2012)
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko.
Nature (2012)
CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor
Natalie Borg;Kwok Soon Wun;Lars Kjer-Nielsen;Matthew Charles James Wilce.
Nature (2007)
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu.
Nature (2014)
A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity
Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks.
Immunity (2003)
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin.
Journal of Experimental Medicine (2013)
Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity
Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell.
Immunity (2008)
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.
Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements.
Nature Immunology (2005)
Prevention of diabetes in non-obese diabetic I-A k transgenic mice
Robyn M. Slattery;Lars Kjer-Nielsen;Janette Allison;Brett Charlton.
Nature (1990)
Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
Isabelle Magalhaes;Karine Pingris;Christine Poitou;Stéphanie Bessoles.
Journal of Clinical Investigation (2015)
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