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Immunology

D-Index
60
Citations
14018
World Ranking
3317
National Ranking
138

Overview

Lars Kjer-Nielsen is affiliated with the University of Melbourne in Australia. Their research primarily spans the fields of Immunology and Microbiology, with additional contributions to Medicine. The scientist's work addresses several specialized subfields, including Immunology, Oncology, Epidemiology, and Genetics.

Their scientific investigations cover a diverse range of topics, notably:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Mycobacterium research and diagnosis
  • Diabetes and associated disorders

Several of Lars Kjer-Nielsen's frequent co-authors include:

  • Alexandra J. Corbett
  • James McCluskey
  • Sara Suliman
  • Sarah K. Iwany
  • Kattya López Tamara

The scientist has published in various academic venues, with notable publications appearing in:

  • The Journal of Infectious Diseases
  • The Journal of Immunology
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent published papers include:

  • "Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls," 2020, The Journal of Infectious Diseases
  • "Dual TCR-α Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation," 2022, The Journal of Immunology
  • "Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo," 2023, Frontiers in Immunology
  • "Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation," 2021, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • MR1 presents microbial vitamin B metabolites to MAIT cells

    Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways

    Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu

  • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

    Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko

  • CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor

    Natalie Borg;Kwok Soon Wun;Lars Kjer-Nielsen;Matthew Charles James Wilce

  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

    Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin

  • A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

    Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks

  • Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

    Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell

  • Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

    Isabelle Magalhaes;Karine Pingris;Christine Poitou;Stéphanie Bessoles

  • T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

    Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements

  • A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

    Sidonia B G Eckle;Richard W Birkinshaw;Lyudmila Kostenko;Alexandra J Corbett

  • Recognition of vitamin B metabolites by mucosal-associated invariant T cells.

    Onisha Patel;Lars Kjer-Nielsen;Jérôme Le Nours;Jérôme Le Nours;Sidonia B. G. Eckle

  • T Cell Allorecognition via Molecular Mimicry

    Whitney Alison Macdonald;Zhenjun Chen;Stephanie Gras;Julia Kate Archbold

  • Prevention of diabetes in non-obese diabetic I-A k transgenic mice

    Robyn M. Slattery;Lars Kjer-Nielsen;Janette Allison;Brett Charlton

  • A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

    Fleur Elizabeth Tynan;Hugh Harrington Reid;Lars Kjer-Nielsen;John J Miles

  • Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

    Daniel G Pellicci;Onisha Patel;Lars Kjer-Nielsen;Siew Siew Pang

  • Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

    Andrew N Keller;Sidonia B G Eckle;Weijun Xu;Ligong Liu

  • A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

    Whitney A Macdonald;Anthony W Purcell;Nicole A Mifsud;Lauren Kate Ely

  • MAIT cells protect against pulmonary Legionella longbeachae infection.

    Huimeng Wang;Criselle D’Souza;Xin Yi Lim;Lyudmila Kostenko

  • Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

    Rangsima Reantragoon;Lars Kjer-Nielsen;Onisha G Patel;Zhenjun Chen

  • The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.

    Natalie A Borg;Lauren Kate Ely;Travis Clarke Beddoe;Whitney Alison Macdonald

  • The Structure of H-2Kb and Kbm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance

    Andrew Ian Webb;Natalie A Borg;Michelle Anne Dunstone;Lars Kjer-Nielsen

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
James McCluskey
James McCluskey University of Melbourne
Anthony W. Purcell
Anthony W. Purcell Monash University
Travis Clarke Beddoe
Travis Clarke Beddoe La Trobe University
Zhenjun Chen
Zhenjun Chen University of Melbourne
Andrew G. Brooks
Andrew G. Brooks University of Melbourne
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Scott R. Burrows
Scott R. Burrows QIMR Berghofer Medical Research Institute
John J. Miles
John J. Miles James Cook University
David P. Fairlie
David P. Fairlie University of Queensland

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