D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 43 Citations 9,274 69 World Ranking 3328 National Ranking 157

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antigen

Lars Kjer-Nielsen spends much of his time researching Antigen, T-cell receptor, T cell, Major histocompatibility complex and Antigen presentation. In his research on the topic of Antigen, Biochemistry is strongly related with Immune system. His work carried out in the field of T-cell receptor brings together such families of science as Molecular biology and Cell biology.

Lars Kjer-Nielsen studies T cell, focusing on Mucosal associated invariant T cell in particular. His Major histocompatibility complex study is concerned with Immunology in general. His studies in Antigen presentation integrate themes in fields like HLA-B Antigens, Human leukocyte antigen and MHC class I.

His most cited work include:

  • MR1 presents microbial vitamin B metabolites to MAIT cells (790 citations)
  • CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor (478 citations)
  • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire (469 citations)

What are the main themes of his work throughout his whole career to date?

Lars Kjer-Nielsen mainly investigates T-cell receptor, T cell, Major histocompatibility complex, Antigen and Cell biology. His T-cell receptor research is multidisciplinary, relying on both Epitope, Molecular biology and Antigen presentation. Lars Kjer-Nielsen works mostly in the field of T cell, limiting it down to topics relating to Human leukocyte antigen and, in certain cases, Peptide.

In the field of Major histocompatibility complex, his study on MHC class I and MHC restriction overlaps with subjects such as Population. His Antigen study combines topics in areas such as Receptor, Biochemistry, Mucosal associated invariant T cell and Virology. The various areas that Lars Kjer-Nielsen examines in his Cell biology study include Protein structure and Transfection.

He most often published in these fields:

  • T-cell receptor (43.42%)
  • T cell (33.55%)
  • Major histocompatibility complex (29.61%)

What were the highlights of his more recent work (between 2012-2021)?

  • T-cell receptor (43.42%)
  • Mucosal associated invariant T cell (13.16%)
  • Antigen (28.95%)

In recent papers he was focusing on the following fields of study:

T-cell receptor, Mucosal associated invariant T cell, Antigen, Immunology and T cell are his primary areas of study. His T-cell receptor study combines topics from a wide range of disciplines, such as MHC class I, CD8, Major histocompatibility complex and Cell biology. Within one scientific family, he focuses on topics pertaining to Antigen presentation under Major histocompatibility complex, and may sometimes address concerns connected to CD1.

His Antigen research is multidisciplinary, incorporating elements of Molecular biology and Interleukin 12. His work deals with themes such as Peripheral, Receptor and Treatment response, which intersect with Immunology. T cell is a primary field of his research addressed under Immune system.

Between 2012 and 2021, his most popular works were:

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways (437 citations)
  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells (352 citations)
  • Recognition of vitamin B metabolites by mucosal-associated invariant T cells. (196 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antigen

His primary areas of study are Mucosal associated invariant T cell, T-cell receptor, Antigen, T cell and Major histocompatibility complex. His research integrates issues of Cell activation and Interleukin 17 in his study of Mucosal associated invariant T cell. His study on T-cell receptor is covered under Immune system.

His T cell study is concerned with the field of Immunology as a whole. He interconnects Plasma protein binding, Cell biology and Antigen presentation in the investigation of issues within Major histocompatibility complex. His CD8 research is multidisciplinary, incorporating perspectives in Cytotoxic T cell, Epstein–Barr virus, Immunopathology and Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

MR1 presents microbial vitamin B metabolites to MAIT cells

Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours.
Nature (2012)

807 Citations

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko.
Nature (2012)

605 Citations

CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor

Natalie Borg;Kwok Soon Wun;Lars Kjer-Nielsen;Matthew Charles James Wilce.
Nature (2007)

584 Citations

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu.
Nature (2014)

502 Citations

A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks.
Immunity (2003)

385 Citations

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin.
Journal of Experimental Medicine (2013)

357 Citations

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell.
Immunity (2008)

319 Citations

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Fleur Elizabeth Tynan;Scott R Burrows;Ashley Maurice Buckle;Craig Steven Clements.
Nature Immunology (2005)

304 Citations

Prevention of diabetes in non-obese diabetic I-A k transgenic mice

Robyn M. Slattery;Lars Kjer-Nielsen;Janette Allison;Brett Charlton.
Nature (1990)

285 Citations

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

Isabelle Magalhaes;Karine Pingris;Christine Poitou;Stéphanie Bessoles.
Journal of Clinical Investigation (2015)

284 Citations

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