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Ram Sasisekharan

Ram Sasisekharan

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
26443
World Ranking
2464
National Ranking
1303

Research.com Recognitions

  • 2014 - Fellow, National Academy of Inventors
  • 2010 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Ram Sasisekharan is affiliated with MIT in the United States and has a research focus spanning several fields within medicine and molecular biology. Their prolific publication record encompasses areas such as infectious diseases, immunology, and radiology.

The scientist's primary fields of study include Medicine and Biochemistry, Genetics, and Molecular Biology. Within these, their work delves deeply into subfields such as Molecular Biology, Infectious Diseases, Radiology, Nuclear Medicine and Imaging, Immunology, and Oncology.

Key research topics covered by their work include SARS-CoV-2 and COVID-19 research, monoclonal and polyclonal antibodies research, glycosylation and glycoproteins research, vaccines and immunoinformatics approaches, Bacillus and Francisella bacterial research, viral infectious diseases and gene expression in insects, and HIV research and treatment.

The scientist has contributed to multiple publications in notable venues. Frequent publication venues include:

  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Molecular Biosciences
  • New England Journal of Medicine
  • Frontiers in Immunology

Recent papers by Ram Sasisekharan feature research on viral evolution and immune responses. These include:

  • Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain (2022, Cell Reports Medicine)
  • Glycans in Virus-Host Interactions: A Structural Perspective (2021, Frontiers in Molecular Biosciences)
  • Insights on the mutational landscape of the SARS-CoV-2 Omicron variant (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • Phase 1 Trial of a Therapeutic Anti-Yellow Fever Virus Human Antibody (2020, New England Journal of Medicine)
  • Preparing for the Future - Nanobodies for Covid-19? (2021, New England Journal of Medicine)

Collaboration has been a prominent aspect of Sasisekharan's research, with frequent coauthors including Rahul Raman, Thomas A. Clark, Nathaniel L. Miller, Kannan Tharakaraman, and Mathuros Ruchirawat.

Over the course of their career, Ram Sasisekharan has been recognized by prestigious organizations with awards such as Fellow of the National Academy of Inventors in 2014 and Fellow of the Indian National Academy of Engineering (INAE) in 2010.

Best Publications

  • Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

    Shiladitya Sengupta;David Eavarone;Ishan Capila;Ganlin Zhao

  • Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

    Taronna R. Maines;Akila Jayaraman;Jessica A. Belser;Debra A. Wadford

  • Roles of heparan-sulphate glycosaminoglycans in cancer

    Ram Sasisekharan;Zachary Shriver;Ganesh Venkataraman;Uma Narayanasami

  • Contaminated heparin associated with adverse clinical events and activation of the contact system.

    Takashi Kei Kishimoto;Karthik Viswanathan;Tanmoy Ganguly;Subbiah Elankumaran

  • Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events.

    Marco Guerrini;Daniela Beccati;Zachary Shriver;Annamaria Naggi

  • Enzymatic degradation of glycosaminoglycans.

    Steffen Ernst;Robert Langer;Charles L. Cooney;Ram Sasisekharan

  • Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift

    S. E. Hensley;S. R. Das;A. L. Bailey;L. M. Schmidt

  • Glycomics: an integrated systems approach to structure-function relationships of glycans.

    Rahul Raman;S Raguram;Ganesh Venkataraman;James C Paulson

  • Structural Insights into Biological Roles of Protein-Glycosaminoglycan Interactions

    Rahul Raman;V. Sasisekharan;Ram Sasisekharan

  • Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin.

    Aarthi Chandrasekaran;Aravind Srinivasan;Rahul Raman;Karthik Viswanathan

  • Heparin and heparan sulfate: biosynthesis, structure and function

    Ram Sasisekharan;Ganesh Venkataraman

  • Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.

    Puneeth Iyengar;Virginia Espina;Terence W. Williams;Ying Lin

  • Modulating angiogenesis: the yin and the yang in ginseng.

    Shiladitya Sengupta;Sue Anne Toh;Lynda A. Sellers;Jeremy N. Skepper

  • Cell surface glypicans are low-affinity endostatin receptors

    S. Ananth Karumanchi;Vivekanand Jha;Ramani Ramchandran;Anil Karihaloo;Anil Karihaloo

  • GLYCOMICS APPROACH TO STRUCTURE-FUNCTION RELATIONSHIPS OF GLYCOSAMINOGLYCANS

    Ram Sasisekharan;Rahul Raman;Vikas Prabhakar

  • Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis

    Dongfang Liu;Zachary Shriver;Ganesh Venkataraman;Yosuf El Shabrawi

  • Sequencing complex polysaccharides.

    Ganesh Venkataraman;Zachary Shriver;Rahul Raman;Ram Sasisekharan

  • Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

    Richard C. Binari;Brian E. Staveley;Wayne A. Johnson;Ranga Godavarti

  • Glycomics: a pathway to a class of new and improved therapeutics.

    Zachary Shriver;S. Raguram;Ram Sasisekharan

  • Outbreak of Adverse Reactions Associated with Contaminated Heparin

    David B. Blossom;Alexander J. Kallen;Priti R. Patel;Alexis Elward

Frequent Co-Authors

Marco Guerrini
Marco Guerrini Istituto G. Ronzoni
Annamaria Naggi
Annamaria Naggi University of Brescia
Giangiacomo Torri
Giangiacomo Torri Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni
Eng Eong Ooi
Eng Eong Ooi National University of Singapore
Benito Casu
Benito Casu Istituto G. Ronzoni
Jacqueline M. Katz
Jacqueline M. Katz Emory University
Jessica A. Belser
Jessica A. Belser Centers for Disease Control and Prevention

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