Terrence M. Tumpey spends much of his time researching Virology, Virus, Influenza A virus subtype H5N1, Influenza A virus and Immunology. Terrence M. Tumpey is interested in Vaccination, which is a branch of Virology. Many of his research projects under Virus are closely connected to Mycoplasma genitalium with Mycoplasma genitalium, tying the diverse disciplines of science together.
His Influenza A virus subtype H5N1 study incorporates themes from Neuraminidase, Hemagglutinin, Interferon, Outbreak and Transmission. The Influenza A virus study combines topics in areas such as Viral disease, Mutation, Microbiology and Virulence. As a part of the same scientific study, Terrence M. Tumpey usually deals with the Immunology, concentrating on Gene expression and frequently concerns with Regulation of gene expression.
His primary areas of investigation include Virology, Virus, Influenza A virus subtype H5N1, Influenza A virus and Viral replication. His studies deal with areas such as Microbiology and Virulence as well as Virology. His Virus research focuses on subjects like Immune system, which are linked to Inflammation.
His work investigates the relationship between Influenza A virus subtype H5N1 and topics such as Viral disease that intersect with problems in Alpha interferon. In his research, Interferon regulatory factors and Gene expression is intimately related to Interferon, which falls under the overarching field of Influenza A virus. As a member of one scientific family, Terrence M. Tumpey mostly works in the field of Viral replication, focusing on Respiratory tract and, on occasion, Respiratory infection and Infectivity.
His main research concerns Virology, Virus, Pandemic, Transmission and Influenza A virus subtype H5N1. His research investigates the connection between Virology and topics such as Virulence that intersect with problems in Lineage. His Influenza A virus, Viral replication, Infectivity, Viral shedding and Titer investigations are all subjects of Virus research.
His Influenza A virus research is multidisciplinary, incorporating perspectives in Cell and Downregulation and upregulation, Gene. His research investigates the connection between Transmission and topics such as Zoonotic Infection that intersect with issues in Strain and Antigenic Diversity. His study in Influenza A virus subtype H5N1 is interdisciplinary in nature, drawing from both Phenotype, Influenza a and Enzootic.
Terrence M. Tumpey focuses on Virus, Virology, Hemagglutinin, Tropism and Pandemic. His work on Virus deals in particular with Influenza A virus subtype H5N1 and Influenza A virus. His work in Virology addresses subjects such as Cell, which are connected to disciplines such as Downregulation and upregulation and Gene.
He interconnects Reverse genetics, Viral pathogenesis, Hemagglutination assay and Antigenic variation in the investigation of issues within Antigenic drift. His work deals with themes such as Infectivity and Hemagglutination, which intersect with Tissue tropism. His Viral etiology research is multidisciplinary, incorporating perspectives in Respiratory virus and Respiratory pathogen.
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Characterization of the reconstructed 1918 Spanish influenza pandemic virus
Terrence M. Tumpey;Christopher F. Basler;Patricia V. Aguilar;Hui Zeng.
Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus
James Stevens;Ola Blixt;Terrence M. Tumpey;Jeffery K. Taubenberger.
Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice
Terrence M. Tumpey;Adolfo García-Sastre;Jeffery K. Taubenberger;Peter Palese.
Journal of Virology (2005)
H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.
Lucy A. Perrone;Julie K. Plowden;Adolfo García-Sastre;Jacqueline M. Katz.
PLOS Pathogens (2008)
A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
Terrence M. Tumpey;Taronna R. Maines;Neal Van Hoeven;Laurel Glaser.
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
John C. Kash;Terrence M. Tumpey;Sean C. Proll;Victoria Carter.
A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence.
Gina M Conenello;Dmitriy Zamarin;Lucy A Perrone;Terrence Tumpey.
PLOS Pathogens (2007)
Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
Xiaocong Yu;Tshidi Tsibane;Patricia A. McGraw;Frances S. House.
Induction of broadly neutralizing H1N1 influenza antibodies by vaccination
Chih Jen Wei;Jeffrey C. Boyington;Patrick M. McTamney;Wing Pui Kong.
Protection against lethal influenza virus challenge by RNA interference in vivo.
Stephen Mark Tompkins;Chia-Yun Lo;Terrence M. Tumpey;Suzanne L. Epstein.
Proceedings of the National Academy of Sciences of the United States of America (2004)
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