World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
82
Citations
20281
World Ranking
1070
National Ranking
28

Medicine

D-Index
82
Citations
20363
World Ranking
16304
National Ranking
545

Overview

Andrew G. Brooks is affiliated with the University of Melbourne in Australia. Their research primarily spans the fields of Immunology and Microbiology with a significant number of publications also categorized under Medicine. Within these broader fields, their work often focuses on Immunology, Epidemiology, Molecular Biology, Infectious Diseases, and Oncology.

The main topics addressed in their research include Immune Cell Function and Interaction, T-cell and B-cell Immunology, interferon and immune responses, Immune Response and Inflammation, Influenza Virus Research Studies, Cytomegalovirus and herpesvirus research, and Immunotherapy and Immune Responses.

Frequent publication venues for Andrew G. Brooks include the Journal of Virology, The Journal of Immunology, and bioRxiv (Cold Spring Harbor Laboratory), with multiple contributions also appearing in Nature Communications and The Journal of Heart and Lung Transplantation.

Their recent papers demonstrate a focus on cellular immune mechanisms and viral infections. Notable publications include:

  • Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C (2021, Nature Communications)
  • CD4 + T cell immunity against cutaneous melanoma encompasses multifaceted MHC II-dependent responses (2024, Science Immunology)
  • CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells (2022, The Journal of Experimental Medicine)
  • CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph (2021, Nature Communications)
  • MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells (2021, mBio)

Collaboration is a significant aspect of their work, with frequent co-authors including Patrick C. Reading, Sarah L. Londrigan, Lucy C. Sullivan, Jamie Rossjohn, and Philippa M. Saunders.

Best Publications

  • Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

    Francisco Borrego;Matthias Ulbrecht;Elisabeth H. Weiss;John E. Coligan

  • Cross-presentation of viral and self antigens by skin-derived CD103 + dendritic cells

    Sammy Bedoui;Paul G Whitney;Jason Waithman;Jason Waithman;Liv Eidsmo

  • Different patterns of peripheral migration by memory CD4 + and CD8 + T cells

    Thomas Gebhardt;Paul G. Whitney;Ali Zaid;Laura K. Mackay

  • Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.

    Jeffrey C. Boyington;Shawn A. Motyka;Peter Schuck;Andrew G. Brooks

  • Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

    Gabrielle T. Belz;Christopher M. Smith;Lauren Kleinert;Patrick Reading

  • A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

    Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks

  • Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

    Michelle D. Tate;Yi-Mo Deng;Jessica E. Jones;Gary P. Anderson

  • NKG2A COMPLEXED WITH CD94 DEFINES A NOVEL INHIBITORY NATURAL KILLER CELL RECEPTOR

    Andrew G. Brooks;Phillip E. Posch;Christopher J. Scorzelli;Francisco Borrego

  • Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection

    Jyh Liang Hor;Paul G. Whitney;Ali Zaid;Andrew G. Brooks

  • Recognition of vitamin B metabolites by mucosal-associated invariant T cells.

    Onisha Patel;Lars Kjer-Nielsen;Jérôme Le Nours;Jérôme Le Nours;Sidonia B. G. Eckle

  • T Cell Allorecognition via Molecular Mimicry

    Whitney Alison Macdonald;Zhenjun Chen;Stephanie Gras;Julia Kate Archbold

  • Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

    Michelle D. Tate;Danielle L. Pickett;Nico van Rooijen;Andrew G. Brooks

  • CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

    Emma J. Petrie;Craig S. Clements;Jie Lin;Lucy C. Sullivan

  • Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1

    Richard M. Coles;Scott N. Mueller;William R. Heath;Francis R. Carbone

  • Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

    Angela Pizzolla;Thi H. O. Nguyen;Jeffrey M. Smith;Andrew G. Brooks

  • Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

    Balasubramanian Krishnamurthy;Nadine L. Dudek;Mark D. McKenzie;Anthony W. Purcell

  • Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

    Daniel G Pellicci;Onisha Patel;Lars Kjer-Nielsen;Siew Siew Pang

  • Cross-Reactive Influenza-Specific Antibody-Dependent Cellular Cytotoxicity Antibodies in the Absence of Neutralizing Antibodies

    Sinthujan Jegaskanda;Emma R. Job;Marit Kramski;Karen Laurie

  • A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

    Whitney A Macdonald;Anthony W Purcell;Nicole A Mifsud;Lauren Kate Ely

  • Herpes Simplex Virus-Specific CD8+ T Cells Can Clear Established Lytic Infections from Skin and Nerves and Can Partially Limit the Early Spread of Virus after Cutaneous Inoculation

    Allison van Lint;Margaret Ayers;Andrew G. Brooks;Richard M. Coles

  • Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4( ) and CD8( ) T Cell Activation to Localized Viral Infection (vol 43, pg 554, 2015)

    Jyh Liang Hor;Paul G Whitney;Ali Zaid;Andrew G Brooks

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
Patrick C. Reading
Patrick C. Reading University of Melbourne
Prashanthan Sanders
Prashanthan Sanders University of Adelaide
James McCluskey
James McCluskey University of Melbourne
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Anthony W. Purcell
Anthony W. Purcell Monash University
Travis Clarke Beddoe
Travis Clarke Beddoe La Trobe University
William R. Heath
William R. Heath University of Melbourne
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Stephen J. Kent
Stephen J. Kent University of Melbourne

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