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Biology and Biochemistry

D-Index
63
Citations
24088
World Ranking
9983
National Ranking
4373

Overview

Adi Diab is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on the field of Medicine, with a specialization in Oncology. Within this domain, their work covers subfields such as Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, and Radiology, Nuclear Medicine and Imaging.

The scientist's main topics of research include:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Melanoma and MAPK Pathways
  • Cutaneous Melanoma Detection and Management
  • Brain Metastases and Treatment
  • Immune Cell Function and Interaction

Recent publications authored by or involving Diab include:

  • "Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response," 2021, Science
  • "Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade," 2021, Nature Medicine
  • "Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma," 2020, Cancer Cell
  • "Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity," 2022, Cancer Cell
  • "Neoadjuvant relatlimab and nivolumab in resectable melanoma," 2022, Nature

Frequent co-authors collaborating with Diab include:

  • Michael A. Davies
  • Sapna P. Patel
  • Rodabe N. Amaria
  • Jennifer L. McQuade
  • Noha Abdel-Wahab

Their work is regularly published in several academic venues, notably:

  • Journal of Clinical Oncology
  • Regular and Young Investigator Award Abstracts
  • Annals of Oncology
  • Cancer Research
  • Journal for ImmunoTherapy of Cancer

Best Publications

  • Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

    V. Gopalakrishnan;V. Gopalakrishnan;C. N. Spencer;C. N. Spencer;L. Nezi;A. Reuben

  • Managing toxicities associated with immune checkpoint inhibitors: Consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group

    I. Puzanov;A. Diab;K. Abdallah;C. O. Bingham

  • Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

    Pei Ling Chen;Whijae Roh;Alexandre Reuben;Zachary A. Cooper

  • Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

    Whijae Roh;Pei Ling Chen;Alexandre Reuben;Christine N. Spencer

  • Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

    Rodabe N. Amaria;Sangeetha M. Reddy;Hussein A. Tawbi;Michael A. Davies

  • Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.

    Miles C. Andrews;Miles C. Andrews;Miles C. Andrews;Connie P.M. Duong;Connie P.M. Duong;Connie P.M. Duong;Vancheswaran Gopalakrishnan;Valerio Iebba;Valerio Iebba

  • Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma

    Catherine S. Grasso;Catherine S. Grasso;Jennifer Tsoi;Mykola Onyshchenko;Gabriel Abril-Rodriguez

  • Combining Radiation and Immunotherapy: A New Systemic Therapy for Solid Tumors?

    Chad Tang;Xiaohong Wang;Hendrick Soh;Steven Seyedin

  • Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells

    Chad Tang;James W. Welsh;Patricia de Groot;Erminia Massarelli

  • Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience

    Omar Mamlouk;Umut Selamet;Shana Machado;Maen Abdelrahim

  • Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

    Rodabe N Amaria;Peter A Prieto;Michael T Tetzlaff;Alexandre Reuben

  • Immune checkpoint inhibitor related myasthenia gravis: single center experience and systematic review of the literature.

    Houssein Safa;Daniel H Johnson;Van Anh Trinh;Theresa E Rodgers

  • Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.

    Adam D. Cohen;David A. Schaer;Cailian Liu;Yanyun Li

  • Checkpoint inhibitor therapy for cancer in solid organ transplantation recipients: an institutional experience and a systematic review of the literature

    Noha Abdel-Wahab;Noha Abdel-Wahab;Houssein Safa;Ala Abudayyeh;Daniel H. Johnson

  • A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.

    Heather L. McArthur;Adi Diab;David B. Page;Jianda Yuan

  • Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity.

    Adam D. Cohen;Adi Diab;Miguel Angel Perales;Miguel Angel Perales;Jedd D. Wolchok;Jedd D. Wolchok

  • Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02)

    Adi Diab;Nizar M. Tannir;Salah Eddine Bentebibel;Patrick Hwu

  • Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation.

    Johannes L. Zakrzewski;Adam A. Kochman;Sydney X. Lu;Theis H. Terwey

  • Endoscopic and Histologic Features of Immune Checkpoint Inhibitor-Related Colitis

    Yinghong Wang;Hamzah Abu-Sbeih;Emily Mao;Noman Ali

  • Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson.

    Yinghong Wang;Hamzah Abu-Sbeih;Emily Mao;Noman Ali

Frequent Co-Authors

Patrick Hwu
Patrick Hwu The University of Texas MD Anderson Cancer Center
Michael A. Davies
Michael A. Davies The University of Texas MD Anderson Cancer Center
Chantale Bernatchez
Chantale Bernatchez The University of Texas MD Anderson Cancer Center
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Cara Haymaker
Cara Haymaker The University of Texas MD Anderson Cancer Center
James P. Allison
James P. Allison The University of Texas MD Anderson Cancer Center
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
Jeffrey E. Gershenwald
Jeffrey E. Gershenwald The University of Texas MD Anderson Cancer Center
Padmanee Sharma
Padmanee Sharma The University of Texas MD Anderson Cancer Center
Cassian Yee
Cassian Yee The University of Texas MD Anderson Cancer Center

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