World's Best Scientists 2026 revealed!

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Immunology

D-Index
90
Citations
36613
World Ranking
1062
National Ranking
573

Medicine

D-Index
90
Citations
36716
World Ranking
12063
National Ranking
6190

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Simon Mallal is affiliated with Vanderbilt University Medical Center in the United States. Their research spans multiple fields, with a primary focus on medicine and immunology and microbiology. Within these broader categories, they have concentrated on subfields including immunology, infectious diseases, molecular biology, epidemiology, and emergency medicine.

The scientist's research topics cover a range of subjects related to immune function, infectious agents, and treatment. Notable areas include immune cell function and interaction, HIV-related health complications and treatments, SARS-CoV-2 and COVID-19 research, HIV research and treatment, vaccines and immunoinformatics approaches, drug-induced adverse reactions, and immunotherapy and immune responses.

Simon Mallal has coauthored numerous publications with several frequent collaborators, such as Elizabeth J. Phillips, Celestine N. Wanjalla, Alessandro Sette, Abha Chopra, and Spyros A. Kalams.

The venues where Mallal has published most frequently include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Nature
  • The Laryngoscope
  • JAMA Network Open

Among recent papers authored or coauthored by Simon Mallal are the following:

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans (2020, Science)
  • Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis (2020, Science Advances)
  • SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron (2022, Cell)
  • Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases (2021, Cell Reports Medicine)
  • α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease (2020, Nature Communications)

The scientist has received recognition through several awards, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2014 and membership in the Association of American Physicians.

Best Publications

  • HLA-B*5701 Screening for Hypersensitivity to Abacavir

    Simon Mallal;Elizabeth Phillips;Giampiero Carosi;Jean-Michel Molina

  • Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

    S. Mallal;S. Mallal;D. Nolan;C. Witt;C. Witt;G. Masel;G. Masel

  • A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

    Jacques Fellay;Kevin V. Shianna;Dongliang Ge;Sara Colombo

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

    Jose Mateus;Alba Grifoni;Alison Tarke;John Sidney

  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

    Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth

  • Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level

    Corey B. Moore;Mina John;Ian R. James;Frank T. Christiansen;Frank T. Christiansen

  • SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron

    Unknown

  • T cells from patients with Parkinson’s disease recognize α-synuclein peptides

    David Sulzer;Roy N. Alcalay;Francesca Garretti;Lucien Cote

  • RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint inhibitors

    Sherene Loi;Sherene Loi;Sathana Dushyanthen;Paul A. Beavis;Roberto Salgado

  • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.

    Simon A Mallal;Mina John;Corey B. Moore;Ian R. James

  • The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases

    Patricia Price;C. Witt;R. Allcock;D. Sayer

  • Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases.

    Alison Tarke;Alison Tarke;John Sidney;Conner K. Kidd;Jennifer M. Dan;Jennifer M. Dan

  • Adaptation of HIV-1 to human leukocyte antigen class I

    Y. Kawashima;K. Pfafferott;J. Frater;P. Matthews

  • Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

    Annalise M. Martin;David Nolan;Silvana Gaudieri;Silvana Gaudieri;Coral Ann Almeida

  • Immune restoration disease after the treatment of immunodeficient HIV‐infected patients with highly active antiretroviral therapy

    M.A. French;N. Lenzo;M. John;S.A. Mallal

  • Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

    David A. Ostrov;Barry J. Grant;Yuri A. Pompeu;John Sidney

  • Common genetic variation and the control of HIV-1 in humans.

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  • High Sensitivity of Human Leukocyte Antigen-B*5701 as a Marker for Immunologically Confirmed Abacavir Hypersensitivity in White and Black Patients

    Michael Saag;Rukmini Balu;Elizabeth Phillips;Philip Brachman

  • Influence of HLA-C Expression Level on HIV Control

    Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen

  • Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data

    J. P.A. Ioannidis;P. S. Rosenberg;J. J. Goedert;L. J. Ashton

  • Common Genetic Variation and the Control of HIV-1 in Humans

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

Frequent Co-Authors

David Nolan
David Nolan Royal Perth Hospital
Mina John
Mina John Royal Perth Hospital
Elizabeth J. Phillips
Elizabeth J. Phillips Vanderbilt University Medical Center
Silvana Gaudieri
Silvana Gaudieri University of Western Australia
Ian James
Ian James Perron Institute for Neurological and Translational Science
Andri Rauch
Andri Rauch University of Bern
Jonathan M. Carlson
Jonathan M. Carlson Microsoft (United States)
Zabrina L. Brumme
Zabrina L. Brumme Simon Fraser University
Bruce D. Walker
Bruce D. Walker Harvard University
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology

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