World's Best Scientists 2026 revealed!

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Immunology

D-Index
46
Citations
11657
World Ranking
4576
National Ranking
199

Overview

Ian James is affiliated with the Perron Institute for Neurological and Translational Science in Australia. Their research spans multiple fields, primarily focusing on medicine and agricultural and biological sciences.

Their work covers key subfields such as insect science, neurology, genetics, infectious diseases, and immunology. Ian James has contributed to topics including amyotrophic lateral sclerosis research, neurogenetic and muscular disorders research, insect symbiosis and bacterial influences, SARS-CoV-2 and COVID-19 research, viral gastroenteritis research and epidemiology, immunodeficiency and autoimmune disorders, and Parkinson's disease mechanisms and treatments.

Ian James has published in several venues, frequently appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology Genetics
  • Pathogens and Immunity
  • Frontiers in Aging Neuroscience
  • Current Biology

Their recent papers include:

  • Generation of a Novel SARS-CoV-2 Sub-genomic RNA Due to the R203K/G204R Variant in Nucleocapsid: Homologous Recombination has Potential to Change SARS-CoV-2 at Both Protein and RNA Level, 2021, Pathogens and Immunity
  • Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype, 2021, Frontiers in Aging Neuroscience
  • Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Rational engineering of a synthetic insect-bacterial mutualism, 2022, Current Biology
  • New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals, 2020, Human Immunology

Ian James frequently collaborates with colleagues in their research, including:

  • Frank Mastaglia
  • Colin Dale
  • Abha Chopra
  • S. Mallal
  • Frances Theunissen

In addition to journal publications, Ian James has contributed to book publishing, with a forthcoming title titled Rethinking Literary Naturalism scheduled for 2025 with Liverpool University Press.

Best Publications

  • Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

    S. Mallal;S. Mallal;D. Nolan;C. Witt;C. Witt;G. Masel;G. Masel

  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

    Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth

  • Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level

    Corey B. Moore;Mina John;Ian R. James;Frank T. Christiansen;Frank T. Christiansen

  • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.

    Simon A Mallal;Mina John;Corey B. Moore;Ian R. James

  • Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

    Annalise M. Martin;David Nolan;Silvana Gaudieri;Silvana Gaudieri;Coral Ann Almeida

  • Immune restoration disease after the treatment of immunodeficient HIV‐infected patients with highly active antiretroviral therapy

    M.A. French;N. Lenzo;M. John;S.A. Mallal

  • Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts

    Annalise M Martin;David Nolan;Ian James;Paul Cameron

  • Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy

    Mina John;Corey B. Moore;Ian R. James;David Nolan

  • Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580

    James G. Conway;Brad McDonald;Janet Parham;Barry Keith

  • Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir

    David Nolan;Richard Upton;Elizabeth McKinnon;Mina John

  • Population Level Analysis of Human Immunodeficiency Virus Type 1 Hypermutation and Its Relationship with APOBEC3G and vif Genetic Variation

    Craig Pace;Jean Keller;David Nolan;Ian James

  • Improving the Effectiveness of Penicillin Allergy De-labeling.

    Jack Bourke;Jack Bourke;Rebecca Pavlos;Ian James;Elizabeth Phillips

  • Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level.

    David Nolan;Emma Hammond;Ian James;Elizabeth McKinnon

  • HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.

    Katherine C. Konvinse;Jason A. Trubiano;Jason A. Trubiano;Rebecca Pavlos;Ian James

  • Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

    Alexandre Harari;Cristina Cellerai;Felicitas Bellutti Enders;Josef Köstler

  • Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy.

    Silvana Gaudieri;Andri Rauch;Andri Rauch;Katja Pfafferott;Eleanor Barnes

  • Population-based V3 Genotypic Tropism Assay: A Retrospective Analysis Using Screening Samples From the A4001029 and MOTIVATE Studies

    Rachel A McGovern;Alexander Thielen;Theresa Mo;Winnie Dong

  • Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing.

    John Archer;Michael S Braverman;Bruce E Taillon;Brian Desany

  • Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.

    Mina John;Elizabeth J. Mckinnon;Ian R. James;David A. Nolan

  • Evidence of Viral Adaptation to HLA Class I-Restricted Immune Pressure in Chronic Hepatitis C Virus Infection

    Silvana Gaudieri;Andri Rauch;Lawrence P. Park;Elizabeth Freitas

  • Proportions of circulating T cells with a regulatory cell phenotype increase with HIV-associated immune activation and remain high on antiretroviral therapy.

    Andrew Lim;Dino Tan;Patricia Price;Adeeba Kamarulzaman

  • Immunological profiles of immune restoration disease presenting as mycobacterial lymphadenitis and cryptococcal meningitis

    D.B.A. Tan;Y.K. Yong;H.Y. Tan;A. Kamarulzaman

  • Divergent Adaptation of Hepatitis C Virus Genotypes 1 and 3 to Human Leukocyte Antigen-Restricted Immune Pressure

    Andri Rauch;Ian James;Katja Pfafferott;David Nolan

Frequent Co-Authors

Simon Mallal
Simon Mallal Vanderbilt University Medical Center
David Nolan
David Nolan Royal Perth Hospital
Mina John
Mina John Royal Perth Hospital
Silvana Gaudieri
Silvana Gaudieri University of Western Australia
Frank T. Christiansen
Frank T. Christiansen University of Western Australia
Frank L. Mastaglia
Frank L. Mastaglia University of Western Australia
Andri Rauch
Andri Rauch University of Bern
Elizabeth J. Phillips
Elizabeth J. Phillips Vanderbilt University Medical Center
Martyn A. French
Martyn A. French University of Western Australia
Hansjakob Furrer
Hansjakob Furrer University of Bern

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