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E. Aubrey Thompson

E. Aubrey Thompson

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
14156
World Ranking
14856
National Ranking
6214

Overview

E. Aubrey Thompson is affiliated with the Mayo Clinic in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans multiple subfields, notably oncology, cancer research, radiology, nuclear medicine and imaging, molecular biology, and neurology.

The scientist's work covers a range of main topics, including cancer immunotherapy and biomarkers, radiomics and machine learning in medical imaging, cancer genomics and diagnostics, breast cancer treatment studies, HER2/EGFR in cancer research, Alzheimer's disease research and treatments, and neuroinflammation and neurodegeneration mechanisms.

Frequent coauthors collaborating with E. Aubrey Thompson include Saranya Chumsri, Jennifer M. Kachergus, Jodi M. Carter, Yaohua Ma, and Matthew P. Goetz. These partnerships reflect ongoing collaborative efforts in their research areas.

Their publications appear prominently in several scientific venues such as Cancer Research, Journal of Clinical Oncology, Clinical Cancer Research, Nature Communications, and Cancers. Specifically, they have published 12 papers in Cancer Research, 7 in Journal of Clinical Oncology, 4 in Clinical Cancer Research, 3 in Nature Communications, and 2 in Cancers.

Among their recent papers are:

  • Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia, 2020, Journal of Clinical Investigation
  • The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice, 2020, The Journal of Pathology
  • Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance, 2022, Nature Communications
  • Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler, 2021, Cancers
  • Characteristics and Spatially Defined Immune (micro)landscapes of Early-stage PD-L1-positive Triple-negative Breast Cancer, 2021, Clinical Cancer Research

Best Publications

  • The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

    R. Salgado;C. Denkert;S. Demaria;N. Sirtaine

  • A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

    Zhenqiang Su;Paweł P. Łabaj;Sheng Li;Jean Thierry-Mieg

  • Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group Part 2 TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors

    Shona Hendry;Roberto Salgado;Thomas Gevaert;Prudence A. Russell;Prudence A. Russell

  • Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis

    Andrew R. Conery;Yanna Cao;E. Aubrey Thompson;Courtney M. Townsend

  • MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

    Krishna R. Kalari;Asha A. Nair;Jaysheel D. Bhavsar;Daniel R. O'Brien

  • The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma

    Verline Justilien;Michael P. Walsh;Syed A. Ali;E. Aubrey Thompson

  • MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer

    Cathy A. Andorfer;Brian M. Necela;E. Aubrey Thompson;Edith A. Perez

  • Atypical Protein Kinase Cι Plays a Critical Role in Human Lung Cancer Cell Growth and Tumorigenicity

    Roderick P. Regala;Capella Weems;Lee Jamieson;John A. Copland

  • Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

    George Vasmatzis;Sarah H. Johnson;Ryan A. Knudson;Rhett P. Ketterling

  • Genomic Analysis Reveals That Immune Function Genes Are Strongly Linked to Clinical Outcome in the North Central Cancer Treatment Group N9831 Adjuvant Trastuzumab Trial

    Edith A. Perez;E. Aubrey Thompson;Karla V. Ballman;S. Keith Anderson

  • 3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer

    Yan W. Asmann;Eric W. Klee;E. Aubrey Thompson;Edith A. Perez

  • The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

    Paula I Gonzalez‐Ericsson;Elisabeth S Stovgaard;Luz F Sua;Emily Reisenbichler

  • Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo

    Nicole R. Murray;Lee Jamieson;Wangsheng Yu;Jie Zhang

  • Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

    Zuzana Kos;Elvire Roblin;Rim S. Kim;Stefan Michiels

  • Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing.

    Zhifu Sun;Yan W. Asmann;Krishna R. Kalari;Brian Bot

  • Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in macrophages

    Brian M. Necela;Weidong Su;E. Aubrey Thompson

  • Protein Kinase C (PKC) βII Induces Cell Invasion through a Ras/Mek-, PKCι/Rac 1-dependent Signaling Pathway

    Jie Zhang;Panos Z. Anastasiadis;Yan Liu;E. Aubrey Thompson

  • Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

    Mercedes Prudencio;Jack Humphrey;Jack Humphrey;Sarah Pickles;Anna-Leigh Brown

  • Folate Receptor-α (FOLR1) Expression and Function in Triple Negative Tumors

    Brian M. Necela;Jennifer A. Crozier;Cathy A. Andorfer;Laura Lewis-Tuffin

  • Evi1 is a survival factor which conveys resistance to both TGFβ- and taxol-mediated cell death via PI3K/AKT

    Y Liu;L Chen;T C Ko;A P Fields

Frequent Co-Authors

Edith A. Perez
Edith A. Perez Mayo Clinic
Yan W. Asmann
Yan W. Asmann Mayo Clinic
Alan P. Fields
Alan P. Fields Mayo Clinic
Zhifu Sun
Zhifu Sun Mayo Clinic
Karla V. Ballman
Karla V. Ballman Cornell University
Jin Jen
Jin Jen Bristol Myers Squibb
Keith L. Knutson
Keith L. Knutson Mayo Clinic
Amylou C. Dueck
Amylou C. Dueck Mayo Clinic
Gary P. Schroth
Gary P. Schroth Illumina (United States)

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