D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 10,745 131 World Ranking 7192 National Ranking 3319

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His scientific interests lie mostly in Protein kinase C, Cell biology, Cancer research, Molecular biology and Signal transduction. His research in Protein kinase C intersects with topics in Activator, Protein kinase A and Effector. His studies deal with areas such as Cell cycle, K562 cells, Apoptosis and Cell growth as well as Cell biology.

Alan P. Fields interconnects Carcinogenesis, A549 cell and Hedgehog signaling pathway in the investigation of issues within Cancer research. The various areas that Alan P. Fields examines in his Molecular biology study include Lamin and Cellular differentiation. His study looks at the relationship between Signal transduction and topics such as Intestinal mucosa, which overlap with Beta-catenin and Adenomatous polyposis coli.

His most cited work include:

  • Protein kinase C isozymes and the regulation of diverse cell responses (633 citations)
  • Atypical protein kinase Cι is an oncogene in human non-small cell lung cancer (229 citations)
  • Elevated Protein Kinase C βII Is an Early Promotive Event in Colon Carcinogenesis (215 citations)

What are the main themes of his work throughout his whole career to date?

Alan P. Fields focuses on Protein kinase C, Cancer research, Cell biology, Carcinogenesis and Protein kinase A. Protein kinase C is closely attributed to Molecular biology in his work. His work deals with themes such as Cancer, Adenocarcinoma, Oncogene, Immunology and Lung cancer, which intersect with Cancer research.

His biological study spans a wide range of topics, including Cell cycle, Intestinal epithelium, Isozyme and Cell growth. His Carcinogenesis research is multidisciplinary, incorporating elements of Tumor progression, Stem cell and Pancreatic cancer. His Protein kinase A research integrates issues from RAC1 and In vivo.

He most often published in these fields:

  • Protein kinase C (41.86%)
  • Cancer research (41.09%)
  • Cell biology (31.01%)

What were the highlights of his more recent work (between 2012-2020)?

  • Cancer research (41.09%)
  • Carcinogenesis (26.36%)
  • Lung cancer (17.05%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Carcinogenesis, Lung cancer, Protein kinase A and Signal transduction. The Cancer research study combines topics in areas such as Phenotype, Immunology, SOX2, KRAS and Adenocarcinoma. His Carcinogenesis study incorporates themes from Pancreatic cancer, Guanine nucleotide exchange factor, RAC1, Tumor progression and Growth factor receptor.

His work carried out in the field of Protein kinase A brings together such families of science as Molecular biology, Gene expression profiling, Oncogene and Effector. His study in the field of Protein kinase C also crosses realms of Platelet-derived growth factor. Cell biology, Phosphorylation and Kinase are all intrinsically tied to his study in Protein kinase C.

Between 2012 and 2020, his most popular works were:

  • The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma (197 citations)
  • Molecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cells. (85 citations)
  • Atypical Protein Kinase Cι as a human oncogene and therapeutic target (64 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Alan P. Fields mainly focuses on Carcinogenesis, Cancer research, Signal transduction, Protein kinase A and Protein kinase C. The concepts of his Carcinogenesis study are interwoven with issues in Phenotype, Ovarian cancer and Gene duplication. His study in Cancer research is interdisciplinary in nature, drawing from both KRAS, Hedgehog and Hedgehog signaling pathway.

His Protein kinase A research is multidisciplinary, incorporating perspectives in Oncogene, Molecular biology, Transforming growth factor beta, In vivo and Effector. His Protein kinase C study is focused on Cell biology in general. His work on Kinase as part of general Cell biology research is frequently linked to Gold Sodium Thiomalate, thereby connecting diverse disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Protein kinase C isozymes and the regulation of diverse cell responses

Edward C. Dempsey;Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields.
American Journal of Physiology-lung Cellular and Molecular Physiology (2000)

1031 Citations

Atypical protein kinase Cι is an oncogene in human non-small cell lung cancer

Roderick P. Regala;Capella Weems;Lee Jamieson;Andras Khoor.
Cancer Research (2005)

347 Citations

Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells.

B A Hocevar;A P Fields.
Journal of Biological Chemistry (1991)

328 Citations

The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma

Verline Justilien;Michael P. Walsh;Syed A. Ali;E. Aubrey Thompson.
Cancer Cell (2014)

293 Citations

Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation.

N.R. Murray;G.P. Baumgardner;D.J. Burns;A.P. Fields.
Journal of Biological Chemistry (1993)

283 Citations

Identification of nuclear beta II protein kinase C as a mitotic lamin kinase.

V L Goss;B A Hocevar;L J Thompson;C A Stratton.
Journal of Biological Chemistry (1994)

252 Citations

Atypical Protein Kinase C ι Protects Human Leukemia Cells against Drug-induced Apoptosis

Nicole R. Murray;Alan P. Fields.
Journal of Biological Chemistry (1997)

244 Citations

Atypical Protein Kinase Cι Plays a Critical Role in Human Lung Cancer Cell Growth and Tumorigenicity

Roderick P. Regala;Capella Weems;Lee Jamieson;John A. Copland.
Journal of Biological Chemistry (2005)

244 Citations

Elevated Protein Kinase C βII Is an Early Promotive Event in Colon Carcinogenesis

Yesim Gökmen-Polar;Nicole R. Murray;Marco A. Velasco;Zoran Gatalica.
Cancer Research (2001)

236 Citations

Overexpression of Protein Kinase C βII Induces Colonic Hyperproliferation and Increased Sensitivity to Colon Carcinogenesis

Nicole R. Murray;Laurie A. Davidson;Robert S. Chapkin;W. Clay Gustafson.
Journal of Cell Biology (1999)

228 Citations

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