What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in PI3K/AKT/mTOR pathway, Protein kinase B, Cancer research, Cell biology and Signal transduction.
His studies deal with areas such as Autophagy, Targeted therapy, Leukemia and Cell growth as well as PI3K/AKT/mTOR pathway.
The various areas that he examines in his Autophagy study include Computational biology and Physiology.
His work carried out in the field of Protein kinase B brings together such families of science as Jurkat cells, Cellular differentiation, GSK-3, Internal medicine and Pharmacology.
His research in Cancer research intersects with topics in Cancer, Kinase, MAPK/ERK pathway, Immunology and PTEN.
Within one scientific family, Alberto M. Martelli focuses on topics pertaining to Nuclear protein under Cell biology, and may sometimes address concerns connected to Nuclear matrix.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health (423 citations)
- Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging (416 citations)
What are the main themes of his work throughout his whole career to date?
Alberto M. Martelli mainly investigates Cancer research, Protein kinase B, PI3K/AKT/mTOR pathway, Cell biology and Signal transduction.
His Cancer research research is multidisciplinary, relying on both Cancer, Targeted therapy, Leukemia, Immunology and MAPK/ERK pathway.
His Protein kinase B research integrates issues from Jurkat cells, Internal medicine and Kinase.
His PI3K/AKT/mTOR pathway research includes elements of Pharmacology and Cell growth.
He has researched Cell biology in several fields, including Molecular biology and Biochemistry.
His study in Signal transduction is interdisciplinary in nature, drawing from both Cellular differentiation and DNA repair.
He most often published in these fields:
- Cancer research (47.54%)
- Protein kinase B (39.34%)
- PI3K/AKT/mTOR pathway (36.39%)
What were the highlights of his more recent work (between 2016-2021)?
- Cancer research (47.54%)
- Signal transduction (24.26%)
- Cancer (10.16%)
In recent papers he was focusing on the following fields of study:
Alberto M. Martelli spends much of his time researching Cancer research, Signal transduction, Cancer, PI3K/AKT/mTOR pathway and Protein kinase B.
His Cancer research research is multidisciplinary, incorporating perspectives in Pancreatic cancer, Cancer cell, Targeted therapy, Leukemia and MAPK/ERK pathway.
His Signal transduction study results in a more complete grasp of Cell biology.
Alberto M. Martelli has included themes like Inducer, Caspase and Protein family in his Cell biology study.
Alberto M. Martelli interconnects mTORC1, Radiosensitivity, Disease and Doxorubicin in the investigation of issues within Cancer.
The Protein kinase B study combines topics in areas such as Wnt signaling pathway, Cytotoxic T cell, Receptor and PTEN.
Between 2016 and 2021, his most popular works were:
- Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging. (116 citations)
- Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. (86 citations)
- Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells. (44 citations)
In his most recent research, the most cited papers focused on:
Alberto M. Martelli mainly focuses on Cancer research, microRNA, Resveratrol, PI3K/AKT/mTOR pathway and Protein kinase B.
His Cancer research research includes themes of Cancer, Gemcitabine, Gene, Hedgehog signaling pathway and Leukemia.
His biological study spans a wide range of topics, including Carcinogenesis, Tumor suppressor gene, Cancer stem cell, Internal medicine and Tumor progression.
His Carcinogenesis study integrates concerns from other disciplines, such as Cell cycle, Bcl-2-associated X protein, Mdm2 and Cell biology.
His work in Resveratrol addresses issues such as Nutraceutical, which are connected to fields such as Inflammation, Antioxidant, Oxidative stress, Metformin and Cancer cell.
His PI3K/AKT/mTOR pathway study focuses mostly on Mechanistic target of rapamycin, mTORC1 and PTEN.
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