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Medicine

D-Index
83
Citations
26918
World Ranking
15546
National Ranking
606

Overview

Massimo Libra is affiliated with the University of Catania in Italy and has contributed extensively to biomedical research, particularly in medicine and biochemistry, genetics, and molecular biology. With a research portfolio of 134 publications in medicine and 107 in biochemistry and molecular biology, their work covers a wide range of interdisciplinary scientific topics.

The primary subfields of study for Massimo Libra include molecular biology, oncology, cancer research, infectious diseases, and immunology. Their research addresses critical topics such as microRNA in disease regulation, cancer-related molecular mechanisms, epigenetics and DNA methylation, nutritional studies and diet, cancer immunotherapy and biomarkers, diet and metabolism studies, and COVID-19 clinical research studies.

Among the recent publications, notable papers include:

  • "Targeting GSK3 and Associated Signaling Pathways Involved in Cancer" (2020) in Cells
  • "Sensitivity assessment of droplet digital PCR for SARS-CoV-2 detection" (2020) in International Journal of Molecular Medicine
  • "SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19" (2020) in Food and Chemical Toxicology
  • "Current and innovative methods for the diagnosis of COVID-19 infection (Review)" (2021) in International Journal of Molecular Medicine
  • "Functional Roles of Matrix Metalloproteinases and Their Inhibitors in Melanoma" (2020) in Cells

Massimo Libra has collaborated frequently with several researchers. The most frequent co-authors are:

  • Luca Falzone
  • Saverio Candido
  • Silvia Vivarelli
  • Giuseppe Gattuso
  • Benjamin Bonavida

Their studies have been published in multiple scientific journals. The most common venues include:

  • International Journal of Molecular Sciences
  • Nutrients
  • Cancers
  • International Journal of Molecular Medicine
  • International Journal of Oncology

Best Publications

  • ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE

    James A. McCubrey;Linda S. Steelman;William H. Chappell;Stephen L. Abrams

  • Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

    James A. McCubrey;Linda S. Steelman;Steven L. Abrams;John T. Lee

  • Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

    Linda S. Steelman;William H. Chappell;Stephen L. Abrams;C. Ruth Kempf

  • Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium.

    Luca Falzone;Salvatore Salomone;Massimo Libra

  • Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

    William H. Chappell;Linda S. Steelman;Jacquelyn M. Long;Ruth C. Kempf

  • Gut Microbiota and Cancer: From Pathogenesis to Therapy

    Silvia Vivarelli;Rossella Salemi;Saverio Candido;Luca Falzone

  • Cutaneous melanoma: From pathogenesis to therapy (Review)

    Giulia C. Leonardi;Luca Falzone;Rossella Salemi;Antonino Zanghì

  • GSK-3 as potential target for therapeutic intervention in cancer.

    James A. McCubrey;Linda S. Steelman;Fred E. Bertrand;Nicole Marie Davis

  • Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia

    L. S. Steelman;S. L. Abrams;J. Whelan;F. E. Bertrand

  • Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

    George Mihai Nitulescu;Denisa Margina;Petras Juzenas;Qian Peng

  • Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mtor cascades which alter therapy response

    James A McCubrey;Linda S Steelman;William H Chappell;Stephen L Abrams

  • Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

    James Andrew McCubrey;Linda S. Steelman;William H. Chappell;Stephen L. Abrams

  • Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.

    L S Steelman;R A Franklin;S L Abrams;W Chappell

  • Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

    Nicole Marie Davis;Melissa Sokolosky;Kristin Stadelman;Stephen L. Abrams

  • Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy

    J A McCubrey;L S Steelman;S L Abrams;F E Bertrand

  • Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

    James A. McCubrey;L. S. Steelman;Fred E. Bertrand;Nicole Marie Davis

  • Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

    Negin Misaghian;Giovanni Ligresti;L. S. Steelman;Fred E. Bertrand

  • PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches.

    Giovanni Ligresti;Loredana Militello;Linda S. Steelman;Andrea Cavallaro

  • Targeting the translational apparatus to improve leukemia therapy: Roles of the PI3K/PTEN/Akt/mTOR pathway

    A. M. Martelli;C. Evangelisti;W. Chappell;S. L. Abrams

  • Akt as a therapeutic target in cancer.

    Linda S Steelman;Kristin M Stadelman;William H Chappell;Stefan Horn

Frequent Co-Authors

James A. McCubrey
James A. McCubrey East Carolina University
Alberto M. Martelli
Alberto M. Martelli University of Bologna
Giuseppe Montalto
Giuseppe Montalto University of Palermo
Lucio Cocco
Lucio Cocco University of Bologna
Melchiorre Cervello
Melchiorre Cervello National Research Council (CNR)
Maurizio Montella
Maurizio Montella Regione Campania
Diego Serraino
Diego Serraino University of Oxford
Demetrios A. Spandidos
Demetrios A. Spandidos University of Crete
Marco Donia
Marco Donia Copenhagen University Hospital
Carlo La Vecchia
Carlo La Vecchia University of Milan

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