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Grant A. Mitchell

Grant A. Mitchell

D-Index & Metrics

Medicine

D-Index
73
Citations
20075
World Ranking
19641
National Ranking
832

Overview

Grant A. Mitchell is affiliated with the University of Montreal in Canada and has contributed significantly to the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their research spans multiple subfields including Molecular Biology, Clinical Biochemistry, Genetics, Surgery, and Physiology.

Their academic output includes work on diverse topics such as Metabolism and Genetic Disorders, Mitochondrial Function and Pathology, Diet and Metabolism Studies, Pancreatic Function and Diabetes, Cellular Transport and Secretion, Genomics and Rare Diseases, and Folate and B Vitamins Research.

Grant A. Mitchell's frequent coauthors include Jean-François Soucy, Youlin Wang, Alexandra Fürtös, Shupei Wang, and Tanguy Demaret.

The scientist has published multiple articles in key venues including Molecular Genetics and Metabolism, Journal of Inherited Metabolic Disease, JIMD Reports, Haemophilia, and bioRxiv (Cold Spring Harbor Laboratory).

Their recent papers of note include:

  • Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice, 2020, PLoS Biology
  • The multiple facets of acetyl-CoA metabolism: Energetics, biosynthesis, regulation, acylation and inborn errors, 2022, Molecular Genetics and Metabolism
  • Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans, 2021, PLoS Genetics
  • Deficiency of 3-hydroxybutyrate dehydrogenase (BDH1) in mice causes low ketone body levels and fatty liver during fasting, 2020, Journal of Inherited Metabolic Disease
  • Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation, 2022, JCI Insight

Best Publications

  • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

    Saverio Cinti;Grant Mitchell;Giorgio Barbatelli;Incoronata Murano

  • A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4).

    Carol J Gallione;Gabriela M Repetto;Eric Legius;Anil K Rustgi

  • Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

    Vamsi K. Mootha;Pierre Lepage;Kathleen Miller;Jakob Bunkenborg

  • Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry.

    Toshiyuki Fukao;Gary D. Lopaschuk;Grant A. Mitchell

  • The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

    Przemyslaw Sapieha;Mirna Sirinyan;Mirna Sirinyan;David Hamel;Karine Zaniolo

  • Excess of De Novo Deleterious Mutations in Genes Associated with Glutamatergic Systems in Nonsyndromic Intellectual Disability

    Fadi F. Hamdan;Julie Gauthier;Yoichi Araki;Da-Ting Lin

  • Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

    Jacques L. Michaud;Francine Boucher;Anna Melnyk

  • Alu sequences in the coding regions of mRNA: a source of protein variability

    Wojciech Makałowski;Grant A. Mitchell;Damian Labuda

  • Medical aspects of ketone body metabolism.

    G A Mitchell;S Kassovska-Bratinova;Y Boukaftane;M F Robert

  • The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice.

    Shu Pei Wang;Nancy Laurin;Jean Himms-Hagen;Michael A. Rudnicki

  • Tyrosinemia: A Review

    Pierre A. Russo;Grant A. Mitchell;Robert M. Tanguay

  • Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis

    Jiang Wei Wu;Shu Pei Wang;Fernando Alvarez;Stéphanie Casavant

  • Ketone body metabolism and its defects

    Toshiyuki Fukao;Grant Mitchell;Jörn Oliver Sass;Tomohiro Hori

  • Recommendations for the management of tyrosinaemia type 1

    Corinne De Laet;Carlo Dionisi-Vici;James Vivian Leonard;Patrick McKiernan

  • The role of the LRPPRC (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome c oxidase) I and COX III mRNA

    Fenghao Xu;Charles Morin;Grant Mitchell;Cameron Ackerley

  • A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation

    Gregory R. Wagner;Dhaval P. Bhatt;Thomas M. O’Connell;J. Will Thompson

  • Population history and its impact on medical genetics in Quebec.

    Laberge Am;Michaud J;Richter A;Lemyre E

  • Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter.

    Jose A. Camacho;Cassandra Obie;Barbara Biery;Barbara K. Goodman

  • Lipolysis and the integrated physiology of lipid energy metabolism

    Shupei Wang;Krishnakant G. Soni;Meriem Semache;Stéphanie Casavant

  • Diagnosis and treatment of tyrosinemia type I: a US and Canadian consensus group review and recommendations

    Jeffrey M Chinsky;Rani Singh;Can Ficicioglu;Clara D M van Karnebeek

Frequent Co-Authors

Toshiyuki Fukao
Toshiyuki Fukao Gifu University
Brian H. Robinson
Brian H. Robinson Hospital for Sick Children
Jacques L. Michaud
Jacques L. Michaud University of Montreal
Eric A. Shoubridge
Eric A. Shoubridge Montreal Neurological Institute and Hospital
Alexey V. Pshezhetsky
Alexey V. Pshezhetsky University of Montreal
Naomi Kondo
Naomi Kondo Gifu University
Jacquetta M. Trasler
Jacquetta M. Trasler McGill University Health Centre
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital
Damian Labuda
Damian Labuda University of Montreal
Emile Levy
Emile Levy University of Montreal

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