Eric Legius

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

Best Publications

• SOX10 mutations in patients with Waardenburg-Hirschsprung disease.

  Véronique Pingault;Nadège Bondurand;Kirsten Kuhlbrodt;Derk E. Goerich

  947
  Citations

• A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4).

  Carol J Gallione;Gabriela M Repetto;Eric Legius;Anil K Rustgi

  829
  Citations

• The NF1 tumor suppressor critically regulates TSC2 and mTOR

  Cory M. Johannessen;Elizabeth E. Reczek;Marianne F. James;Hilde Brems

  674
  Citations

• Neurofibromatosis type 1

  Legius E;Descheemaeker Mj;Fryns Jp;Van den Berghe H

  597
  Citations

• Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.

  Hilde Brems;Magdalena Chmara;Magdalena Chmara;Mourad Sahbatou;Ellen Denayer

  525
  Citations

• Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis.

  Eric Legius;Eric Legius;Douglas A. Marchuk;Francis S. Collins;Thomas W. Glover

  469
  Citations

• Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation.

  E Legius;L Messiaen;P Wolkenstein;P Pancza

  468
  Citations

• PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies

  Thomas De Raedt;Eline Beert;Eric Pasmant;Armelle Luscan

  450
  Citations

• Intelligence and psychosocial adjustment in velocardiofacial syndrome: a study of 37 children and adolescents with VCFS.

  Ann Swillen;Koenraad Devriendt;Eric Legius;Benedicte Eyskens

  414
  Citations

• Mechanisms in the pathogenesis of malignant tumours in neurofibromatosis type 1

  Hilde Brems;Eline Beert;Thomy de Ravel;Eric Legius

  385
  Citations

• Elevated risk for MPNST in NF1 microdeletion patients.

  T. De Raedt;H. Brems;P. Wolkenstein;D. Vidaud

  341
  Citations

• Cognitive function and academic performance in neurofibromatosis 1 : Consensus statement from the NF1 Cognitive Disorders Task Force

  K. N. North;V. Riccardi;C. Samango-Sprouse;R. Ferner

  341
  Citations

• Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia.

  J R Hurvitz;W M Suwairi;W Van Hul;H El-Shanti

  333
  Citations

• PTPN11 mutations in LEOPARD syndrome

  Eric Legius;C Schrander-Stumpel;E Schollen;C Pulles-Heintzberger

  313
  Citations

• Communication with close and distant relatives in the context of genetic testing for hereditary breast and ovarian cancer in cancer patients.

  Erna Claes;Gerry Evers-Kiebooms;Andrea Boogaerts;Marleen Decruyenaere

  308
  Citations

• CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia

  Susanne Kohl;Balazs Varsanyi;Balazs Varsanyi;Gesine Abadin Antunes;Britta Baumann

  268
  Citations

• Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

  Ophélia Maertens;Hans Prenen;Maria Debiec-Rychter;Agnieszka Wozniak

  263
  Citations

• Guidelines for the Li–Fraumeni and heritable TP53-related cancer syndromes

  Thierry Frebourg;Svetlana Bajalica Lagercrantz;Carla Oliveira;Rita Magenheim

  247
  Citations

• Atypical Neurofibromas in Neurofibromatosis Type 1 Are Premalignant Tumors

  Eline Beert;Hilde Brems;Bruno Daniëls;Ivo De Wever

  242
  Citations

• Intelligence and psychosocial adjustment in velo-cardio-facial syndrome: a study of 37 children and adolescents with VCFS

  Ann Swillen;Koenraad Devriendt;Eric Legius;B Eyskens

  5
  Citations