Peter Marynen mostly deals with Molecular biology, Genetics, Cancer research, Tyrosine kinase and Gene. His studies in Molecular biology integrate themes in fields like Syndecan 1, Heparan sulfate, Acute lymphocytic leukemia, Complementary DNA and MALT lymphoma. His study in Cancer research is interdisciplinary in nature, drawing from both Cellular differentiation, Gene rearrangement, Immunology and Acute leukemia.
His research integrates issues of Karyotype and JAK2 Gene Mutation in his study of Immunology. His work deals with themes such as Receptor tyrosine kinase and Imatinib mesylate, which intersect with Tyrosine kinase. Within one scientific family, Peter Marynen focuses on topics pertaining to Lymphoma under Gene, and may sometimes address concerns connected to Nucleic acid thermodynamics.
His primary scientific interests are in Genetics, Molecular biology, Cancer research, Gene and Chromosomal translocation. His Molecular biology research is multidisciplinary, incorporating perspectives in Fusion gene, Complementary DNA, Peptide sequence, Cytogenetics and Fluorescence in situ hybridization. His Fluorescence in situ hybridization research integrates issues from Gene rearrangement, Chromosome 12 and Pathology.
His Cancer research research includes themes of Immunology and Tyrosine kinase, ABL. Peter Marynen has included themes like Imatinib and Receptor tyrosine kinase in his Tyrosine kinase study. His studies deal with areas such as Myeloid, Acute lymphocytic leukemia and Lymphoma as well as Chromosomal translocation.
His primary areas of study are Genetics, Cancer research, Gene, Gene duplication and Cell biology. His Cancer research research includes elements of Tyrosine kinase and PDGFRA. Peter Marynen interconnects Gene rearrangement, Breakpoint, Non-allelic homologous recombination, Comparative genomic hybridization and Hypopituitarism in the investigation of issues within Gene duplication.
His study looks at the intersection of Comparative genomic hybridization and topics like B-cell lymphoma with Chromosomal translocation. His studies examine the connections between Phenotype and genetics, as well as such issues in Ubiquitin ligase, with regards to Molecular biology, Proteasome, Drosophila melanogaster and Wnt signaling pathway. The Molecular biology study combines topics in areas such as Cleavage factor, Signal transduction and IκBα.
Peter Marynen mainly focuses on Cancer research, Genetics, Gene duplication, Dasatinib and PDGFRA. His Cancer research research incorporates themes from Tyrosine kinase, Cellular differentiation, Immunology and Kinase activity. His Tyrosine kinase research is multidisciplinary, relying on both Fusion protein and Lymphoma.
His Immunology research incorporates elements of Internal medicine, Chemotherapy and Chromosomal translocation. His work carried out in the field of Gene duplication brings together such families of science as Molecular biology, Gene rearrangement and Comparative genomic hybridization. The study incorporates disciplines such as X-linked intellectual disability, Ubiquitin ligase and Point mutation in addition to Molecular biology.
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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Ross L. Levine;Ross L. Levine;Martha Wadleigh;Jan Cools;Benjamin L. Ebert;Benjamin L. Ebert.
Cancer Cell (2005)
Gene prioritization through genomic data fusion.
Stein Aerts;Diether Lambrechts;Sunit Maity;Peter Van Loo.
Nature Biotechnology (2006)
Allele-specific copy number analysis of tumors
Peter Van Loo;Silje H. Nordgard;Silje H. Nordgard;Ole Christian Lingjærde;Hege G. Russnes.
Proceedings of the National Academy of Sciences of the United States of America (2010)
The Apoptosis Inhibitor Gene API2 and a Novel 18q Gene,MLT, Are Recurrently Rearranged in the t(11;18)(q21;q21) Associated With Mucosa-Associated Lymphoid Tissue Lymphomas
Judith Dierlamm;Mathijs Baens;Iwona Wlodarska;Margarita Stefanova-Ouzounova.
Blood (1999)
Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males.
Hilde Van Esch;Marijke Bauters;Jaakko Ignatius;Mieke Jansen.
American Journal of Human Genetics (2005)
Fusion of TEL, the ETS-Variant Gene 6 (ETV6), to the Receptor-Associated Kinase JAK2 as a Result of t(9; 12) in a Lymphoid and t(9; 15; 12) in a Myeloid Leukemia
Pieter Peeters;Sophie D. Raynaud;Jan Cools;Iwona Wlodarska.
Blood (1997)
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants
Maria Debiec-Rychter;Jan Cools;Herlinde Dumez;Raf Sciot.
Gastroenterology (2005)
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
C Graux;Jan Cools;C Melotte;H Quentmeier.
Nature Genetics (2004)
A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation
A. Carrie;L. Jun;T. Bienvenu;M.C. Vinet.
Nature Genetics (1999)
Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.
G David;V Lories;B Decock;P Marynen.
Journal of Cell Biology (1990)
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