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Rudolf Zechner

Rudolf Zechner

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Biology and Biochemistry
Austria
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
40701
World Ranking
1355
National Ranking
8

Medicine

D-Index
101
Citations
40581
World Ranking
7927
National Ranking
40

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Austria Leader Award
  • 2025 - Research.com Biology and Biochemistry in Austria Leader Award
  • 2019 - Member of the National Academy of Sciences
  • 2007 - Wittgenstein Award

Overview

Rudolf Zechner is affiliated with the University of Graz in Austria. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Physiology, Biochemistry, Surgery, Molecular Biology, and Epidemiology.

Their main research topics include:

  • Adipose Tissue and Metabolism
  • Lipid metabolism and biosynthesis
  • Pancreatic function and diabetes
  • Endoplasmic Reticulum Stress and Disease
  • Fatty Acid Research and Health
  • Cancer, Lipids, and Metabolism
  • Cancer, Hypoxia, and Metabolism

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Journal of Lipid Research
  • Journal of Biological Chemistry
  • Nature Metabolism

Recent papers authored or co-authored by Rudolf Zechner include:

  • Lipolysis: cellular mechanisms for lipid mobilization from fat stores, 2021, Nature Metabolism
  • Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis, 2021, Cell
  • ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids, 2022, Nature
  • Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides, 2020, Proceedings of the National Academy of Sciences
  • The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure, 2020, Cell Reports Medicine

Frequent co-authors working alongside Rudolf Zechner include:

  • Peter Hofer
  • Martina Schweiger
  • Renate Schreiber
  • Monika Oberer
  • G Grabner

Over the course of their career, Rudolf Zechner has received several awards, notably membership in the National Academy of Sciences in 2019 and the Wittgenstein Award in 2007.

Best Publications

  • Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase

    Robert Zimmermann;Juliane G. Strauss;Guenter Haemmerle;Gabriele Schoiswohl

  • Cellular fatty acid metabolism and cancer

    Erin Currie;Almut Schulze;Rudolf Zechner;Tobias C. Walther

  • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

    Guenter Haemmerle;Achim Lass;Robert Zimmermann;Gregor Gorkiewicz

  • FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

    Rudolf Zechner;Robert Zimmermann;Thomas O. Eichmann;Sepp D. Kohlwein

  • Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.

    Achim Lass;Robert Zimmermann;Guenter Haemmerle;Monika Riederer

  • Adipose Triglyceride Lipase and Hormone-sensitive Lipase Are the Major Enzymes in Adipose Tissue Triacylglycerol Catabolism

    Martina Schweiger;Renate Schreiber;Guenter Haemmerle;Achim Lass

  • Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

    Aliki Kosteli;Eiji Sugaru;Guenter Haemmerle;Jayne F. Martin

  • Hormone-sensitive Lipase Deficiency in Mice Causes Diglyceride Accumulation in Adipose Tissue, Muscle, and Testis

    Guenter Haemmerle;Robert Zimmermann;Marianne Hayn;Christian Theussl

  • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

    Guenter Haemmerle;Tarek Moustafa;Gerald Woelkart;Sabrina Büttner

  • Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

    Achim Lass;Robert Zimmermann;Monika Oberer;Rudolf Zechner

  • A switch from white to brown fat increases energy expenditure in cancer-associated cachexia.

    Michele Petruzzelli;Martina Schweiger;Renate Schreiber;Ramon Campos-Olivas

  • Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

    Rudolf Zechner;Petra C. Kienesberger;Guenter Haemmerle;Robert Zimmermann

  • Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

    Suman K. Das;Sandra Eder;Silvia Schauer;Clemens Diwoky

  • Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

    K Aalto-Setälä;E A Fisher;X Chen;T Chajek-Shaul

  • Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

    Moshe S. Weintraub;Rudolf Zechner;Anne Brown;Shlomo Eisenberg

  • Cytosolic lipolysis and lipophagy: two sides of the same coin

    Rudolf Zechner;Frank Madeo;Dagmar Kratky

  • Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.

    P. H. Weinstock;C. L. Bisgaier;K. Aalto-Setala;H. Radner

  • Lipolysis: cellular mechanisms for lipid mobilization from fat stores.

    Gernot F. Grabner;Hao Xie;Martina Schweiger;Rudolf Zechner

  • Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

    Brendan N. Reid;Gene P. Ables;Oleg A. Otlivanchik;Gabriele Schoiswohl

  • Obese Yeast: Triglyceride Lipolysis Is Functionally Conserved from Mammals to Yeast

    C F Kurat;Klaus Natter;Julia Petschnigg;Heimo Wolinski

Frequent Co-Authors

Guenter Haemmerle
Guenter Haemmerle University of Graz
Achim Lass
Achim Lass University of Graz
Robert Zimmermann
Robert Zimmermann University of Graz
Gert M. Kostner
Gert M. Kostner University of Graz
Bernd Mayer
Bernd Mayer University of Graz
Wolfgang Sattler
Wolfgang Sattler Medical University of Graz
Rolf Breinbauer
Rolf Breinbauer Graz University of Technology
Jan L. Breslow
Jan L. Breslow Rockefeller University
Robert V. Farese
Robert V. Farese Harvard University
Sepp D. Kohlwein
Sepp D. Kohlwein University of Graz

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