World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
130
Citations
56378
World Ranking
2507
National Ranking
1413

Research.com Recognitions

  • 2006 - Distinguished Scientist Award, American Heart Association
  • 1997 - Member of the National Academy of Medicine (NAM)
  • 1995 - Member of the National Academy of Sciences
  • 1994 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 1984 - E. Mead Johnson Award, Society for Pediatric Research
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jan L. Breslow is affiliated with Rockefeller University in the United States. Their research primarily spans the field of medicine with a focus on several subfields including physiology, epidemiology, dermatology, molecular biology, and endocrinology, diabetes, and metabolism.

They have contributed notably to the following main topics of research:

  • Diet and metabolism studies
  • Diet, Metabolism, and Disease
  • Liver Disease Diagnosis and Treatment
  • Skin Protection and Aging
  • Metabolomics and Mass Spectrometry Studies
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases

Jan L. Breslow has published in various scientific venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Journal of Clinical and Translational Science
  • OMICS A Journal of Integrative Biology

Some recent publications include:

  • "Excess dietary fructose does not alter gut microbiota or permeability in humans: A pilot randomized controlled study," 2021, Journal of Clinical and Translational Science
  • "Obesity and ethnicity alter gene expression in skin," 2020, Scientific Reports
  • "The Application of Spearman Partial Correlation for Screening Predictors of Weight Loss in a Multiomics Dataset," 2022, OMICS A Journal of Integrative Biology
  • "Excess Dietary Fructose Does Not Alter Gut Microbiota or Permeability in Humans: A Randomized Controlled Pilot Study," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Obesity and Race Alter Gene Expression in Skin," 2020, bioRxiv (Cold Spring Harbor Laboratory)

Jan L. Breslow's frequent co-authors include:

  • José O. Alemán
  • Peter R. Holt
  • Jeanne Walker
  • Sandra Garcet
  • Christopher E. Mason

Throughout their career, Jan L. Breslow has received several awards and recognitions:

  • Distinguished Scientist Award, American Heart Association, 2006
  • Member of the National Academy of Medicine (NAM), 1997
  • Member of the National Academy of Sciences, 1995
  • Robert J. and Claire Pasarow Foundation Medical Research Award, 1994
  • E. Mead Johnson Award, Society for Pediatric Research, 1984
  • Member of the Association of American Physicians

Best Publications

  • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

    Andrew S. Plump;Jonathan D. Smith;Tony Hayek;Katriina Aalto-Setälä

  • Low-Density Lipoprotein Subclass Patterns and Risk of Myocardial Infarction

    Melissa A. Austin;Jan L. Breslow;Charles H. Hennekens;Julie E. Buring

  • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

    Yutaka Nakashima;Andrew S. Plump;Elaine W. Raines;Jan L. Breslow

  • Moderate Alcohol Intake, Increased Levels of High-Density Lipoprotein and Its Subfractions, and Decreased Risk of Myocardial Infarction

    Gaziano Jm;Buring Je;Breslow Jl;Goldhaber Sz

  • Upregulation of VCAM-1 and ICAM-1 at Atherosclerosis-Prone Sites on the Endothelium in the ApoE-Deficient Mouse

    Yutaka Nakashima;Elaine W. Raines;Andrew S. Plump;Jan L. Breslow

  • Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

    Jason K. Kim;Jonathan J. Fillmore;Yan Chen;Chunli Yu

  • Fasting Triglycerides, High-Density Lipoprotein, and Risk of Myocardial Infarction

    J M Gaziano;C H Hennekens;C J O'Donnell;J L Breslow

  • Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice.

    Yasushi Ito;Neal Azrolan;Anita O'Connell;Annemarie Walsh

  • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

    W Palinski;V A Ord;A S Plump;J L Breslow

  • Glycosylated Hemoglobins and Long-Term Blood Glucose Control in Diabetes Mellitus

    K H Gabbay;K Hasty;J L Breslow;R C Ellison

  • Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.

    Moshe S. Weintraub;Shlomo Eisenberg;Jan L. Breslow

  • n−3 Fatty acids and cardiovascular disease

    Jan L Breslow

  • Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes.

    Vassilis I. Zannis;Jan L. Breslow;Gerd Utermann;Robert W. Mahley

  • Whole population, genome-wide mapping of hidden relatedness

    Alexander Gusev;Jennifer K. Lowe;Markus Stoffel;Mark J. Daly

  • Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

    H K Das;J Mcpherson;G A P Bruns;S K Karathanasis

  • Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment.

    Kara N. Maxwell;Edward A. Fisher;Jan L. Breslow

  • Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

    Kara N. Maxwell;Raymond E. Soccio;Elizabeth M. Duncan;Ephraim Sehayek

  • Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

    K Aalto-Setälä;E A Fisher;X Chen;T Chajek-Shaul

  • Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism

    David Q. Shih;Markus Bussen;Ephraim Sehayek;Meenakshisundaram Ananthanarayanan

  • Intracellular Cholesterol Transport

    Raymond E. Soccio;Jan L. Breslow

Frequent Co-Authors

Jeffrey M. Friedman
Jeffrey M. Friedman Rockefeller University
Alan R. Tall
Alan R. Tall Columbia University
Jonathan D. Smith
Jonathan D. Smith Cleveland Clinic
Markus Stoffel
Markus Stoffel University of Geneva
Edward A. Fisher
Edward A. Fisher New York University
David Altshuler
David Altshuler Harvard University
Ira J. Goldberg
Ira J. Goldberg New York University
Rudolf Zechner
Rudolf Zechner University of Graz
Itsik Pe'er
Itsik Pe'er Columbia University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital

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