World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
127
Citations
76433
World Ranking
461
National Ranking
295

Research.com Recognitions

  • 2020 - Fellow of the Royal Society of Edinburgh
  • 2012 - Fellow of the American Academy of Arts and Sciences
  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Tom Curran is affiliated with Children's Mercy Hospital in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a primary focus on medicine. Their research encompasses molecular biology, genetics, biophysics, cancer research, and immunology.

Their work covers several main topics, including:

  • Genomics and Rare Diseases
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Glioma Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Genomic Variations and Chromosomal Abnormalities
  • Cancer Genomics and Diagnostics
  • Genomics and Phylogenetic Studies

Recent notable publications by Tom Curran include:

  • "Genomic answers for children: Dynamic analyses of >1000 pediatric rare disease genomes" (2022) published in Genetics in Medicine
  • "A spectroscopic liquid biopsy for the earlier detection of multiple cancer types" (2023) published in British Journal of Cancer
  • "Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality" (2021) published in Cell Reports
  • "Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort" (2023) published in Nature Communications
  • "Pangenome graphs improve the analysis of structural variants in rare genetic diseases" (2024) published in Nature Communications

The scientist's research appears frequently in journals such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cell Reports, Zenodo (CERN European Organization for Nuclear Research), and Genetics in Medicine.

Some of the frequent collaborators include:

  • Emily Farrow
  • Warren Cheung
  • Isabelle Thiffault
  • Tomi Pastinen
  • Carl Schwendinger-Schreck

Tom Curran has received several honors, including being named a Fellow of the Royal Society of Edinburgh in 2020, a Fellow of the American Academy of Arts and Sciences in 2012, and a Fellow of the American Association for the Advancement of Science (AAAS) in 1994.

Best Publications

  • Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

    James I. Morgan;Tom Curran

  • Prediction of central nervous system embryonal tumour outcome based on gene expression

    Scott L. Pomeroy;Pablo Tamayo;Michelle Gaasenbeek;Lisa M. Sturla

  • Expression of c-fos protein in brain: metabolic mapping at the cellular level

    S. M. Sagar;Frank R Sharp;T. Curran

  • Mapping patterns of c-fos expression in the central nervous system after seizure

    James I. Morgan;Donna R. Cohen;James L. Hempstead;Tom Curran

  • Fos and Jun: the AP-1 connection.

    Tom Curran;B.Robert Franza

  • A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

    G. D'arcangelo;G. G. Miao;Shu-Cheng Chen;H. D. Soares

  • Redox regulation of fos and jun DNA-binding activity in vitro

    Cory Abate;Lekha Patel;Frank J. Rauscher;Tom Curran

  • Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

    Tsonwin Hai;Tom Curran

  • Induction of c- fos gene and protein by growth factors precedes activation of c- myc

    Rolf Müller;Rodrigo Bravo;Jean Burckhardt;Tom Curran

  • A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

    Vikas P. Sukhatme;Xinmin Cao;Louise C. Chang;Chon-Hwa Tsai-Morris

  • Role of ion flux in the control of c-fos expression.

    James I. Morgan;Tom Curran

  • Stimulus-transcription coupling in neurons: role of cellular immediate-early genes.

    James I. Morgan;Tom Curran

  • Redox activation of Fos‐Jun DNA binding activity is mediated by a DNA repair enzyme.

    S. Xanthoudakis;G. Miao;F. Wang;Y.-C. E. Pan

  • Continuous c-fos expression precedes programmed cell death in vivo

    Richard J. Smeyne;Montserrat Vendrell;Michael Hayward;Michael Hayward;Suzanne J. Baker

  • The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun.

    Jain J;McCaffrey Pg;Miner Z;Miner Z;Kerppola Tk

  • Reelin Is a Ligand for Lipoprotein Receptors

    Gabriella D'Arcangelo;Ramin Homayouni;Lakhu Keshvara;Dennis S Rice

  • Radial glia cells are candidate stem cells of ependymoma

    Michael D. Taylor;Helen Poppleton;Christine Fuller;Xiaoping Su

  • Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

    T Curran;M B Gordon;K L Rubino;L C Sambucetti

  • FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA.

    T Curran;G Peters;C Van Beveren;N M Teich

  • Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

    S Xanthoudakis;T Curran

Frequent Co-Authors

James I. Morgan
James I. Morgan St. Jude Children's Research Hospital
Tom K. Kerppola
Tom K. Kerppola University of Michigan–Ann Arbor
Gabriella D'Arcangelo
Gabriella D'Arcangelo Rutgers, The State University of New Jersey
Richard J. Smeyne
Richard J. Smeyne Thomas Jefferson University
Richard J. Gilbertson
Richard J. Gilbertson University of Cambridge
Kazunori Nakajima
Kazunori Nakajima Keio University
Peter J. McKinnon
Peter J. McKinnon St. Jude Children's Research Hospital
Frank J. Rauscher
Frank J. Rauscher The Wistar Institute
John A. Connor
John A. Connor University of New Mexico
Jie Zheng
Jie Zheng University of California, Los Angeles

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