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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
12869
World Ranking
16522
National Ranking
6842

Overview

Jie Zheng is affiliated with the University of California, Los Angeles in the United States and has an active research profile primarily focused on medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, ophthalmology, radiology, nuclear medicine and imaging, public health, environmental and occupational health, and cell biology.

Their research topics reflect a strong focus on ocular health and molecular signaling pathways. These topics include:

  • Retinal Diseases and Treatments
  • Corneal Surgery and Treatments
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Wnt/β-catenin signaling in development and cancer
  • Ocular Surface and Contact Lens
  • Cancer-related gene regulation

Jie Zheng has contributed several recent publications in notable journals. These include:

  • "HIF-1α in myocardial ischemia-reperfusion injury (Review)" (2021) published in Molecular Medicine Reports
  • "Human limbal epithelial stem cell regulation, bioengineering and function" (2021) published in Progress in Retinal and Eye Research
  • "Premise and peril of Wnt signaling activation through GSK-3β inhibition" (2022) published in iScience
  • "Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine" (2021) published in RSC Chemical Biology
  • "Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study" (2022) published in The AAPS Journal

Their frequent collaborators include Sophie X. Deng, Sarah Robertson, Clémence Bonnet, Hua Mei, and Luis Sanchez.

Jie Zheng's publications appear most often in these venues:

  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience
  • Genes
  • Biochemistry and Biophysics Reports

Best Publications

  • Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

    Yuan Gao;J. Bradley Dickerson;Fukun Guo;Jie Zheng

  • THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

    Stephen W. White;Jie Zheng;Yo ng-Mei Zhang;Charles O. Rock

  • Large-Scale Sequence Analysis of Avian Influenza Isolates

    John C. Obenauer;Jackie Denson;Perdeep K. Mehta;Xiaoping Su

  • Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled.

    Hing-C. Wong;Audrey Bourdelas;Anke Krauss;Ho-Jin Lee

  • PDZ domains and their binding partners: structure, specificity, and modification

    Ho-Jin Lee;Jie J Zheng

  • Macrophage Wnt7b is critical for kidney repair and regeneration

    Shuei Liong Lin;Bing Li;Sujata Rao;Eun Jin Yeo

  • A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

    Chi Hon Lee;Benjamin Leung;Mark A. Lemmon;Jie Zheng

  • Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

    Xiaodong Wu;Beatrice Knudsen;Stephan M Feller;Jie Zheng

  • Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

    Jie Zheng;Sean M. Cahill;Mark A. Lemmon;David Fushman

  • Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia

    Barthelemy Diouf;Kristine R. Crews;Glen Lew;Deqing Pei

  • An Antagonist of Dishevelled Protein-Protein Interaction Suppresses β-Catenin–Dependent Tumor Cell Growth

    Naoaki Fujii;Liang You;Zhidong Xu;Kazutsugu Uematsu

  • Crystal Structure of a Full-Length beta-Catenin

    Yi Xing;Ken Ichi Takemaru;Jing Liu;Jason D. Berndt

  • Identification of a specific inhibitor of the Dishevelled PDZ domain

    Jufang Shan;De Li Shi;Junmei Wang;Jie Zheng

  • Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled

    David Grandy;Jufang Shan;Xinxin Zhang;Sujata Rao

  • Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway.

    Hing C. Wong;Junhao Mao;Jason T. Nguyen;Shamala Srinivas

  • The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd.

    Yazhou Zhang;Yang Wang;Xiaofeng Li;Jianhong Zhang

  • Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization

    Matias Simons;William J. Gault;Daniel Gotthardt;Rajeev Rohatgi

  • Physiological signals and oncogenesis mediated through Crk family adapter proteins.

    Stephan M. Feller;Guido Posern;Jan Voss;Christian Kardinal

  • Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway

    Peter Maye;Jie Zheng;Lin Li;Dianqing Wu

  • The solution structure of acyl carrier protein from Mycobacterium tuberculosis.

    Hing Cm Wong;Gaohua Liu;Yong-Mei Zhang;Charles Om Rock;Charles Om Rock

Frequent Co-Authors

David Cowburn
David Cowburn Albert Einstein College of Medicine
Dianqing Wu
Dianqing Wu Yale University
Beatrice S. Knudsen
Beatrice S. Knudsen University of Utah
Yi Zheng
Yi Zheng Cincinnati Children's Hospital Medical Center
Yong-Mei Zhang
Yong-Mei Zhang Medical University of South Carolina
George Barany
George Barany University of Minnesota
Mary V. Relling
Mary V. Relling St. Jude Children's Research Hospital
Hidesaburo Hanafusa
Hidesaburo Hanafusa Osaka Bioscience Institute
Charles O. Rock
Charles O. Rock St. Jude Children's Research Hospital
William E. Evans
William E. Evans St. Jude Children's Research Hospital

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