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Naofumi Mukaida

Naofumi Mukaida

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Medicine
Japan
2023

D-Index & Metrics

Immunology

D-Index
116
Citations
44794
World Ranking
383
National Ranking
15

Medicine

D-Index
116
Citations
44883
World Ranking
4391
National Ranking
93

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Naofumi Mukaida is affiliated with Kanazawa University in Japan and has a focused research portfolio in Medicine and Immunology and Microbiology. Their work spans various subfields including Immunology, Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, and Hematology.

Their recent scholarly contributions include papers published between 2020 and 2023, demonstrating involvement in tumor microenvironment signaling, immune response modulation, and liver disease mechanisms. Notable publications include:

  • CCL4 Signaling in the Tumor Microenvironment, 2020, Advances in Experimental Medicine and Biology
  • Two-Faced Roles of Tumor-Associated Neutrophils in Cancer Development and Progression, 2020, International Journal of Molecular Sciences
  • C C chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice, 2021, Metabolism
  • Immune Mechanisms of Pulmonary Fibrosis with Bleomycin, 2023, International Journal of Molecular Sciences
  • CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status, 2022, Metabolism

Research topics predominantly address chemokine receptors and signaling, immune cells in cancer, immunotherapy and immune responses, immune cell function and interaction, liver disease diagnosis and treatment, protease and inhibitor mechanisms, and venous thromboembolism diagnosis and management.

  • Chemokine receptors and signaling
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Liver Disease Diagnosis and Treatment
  • Protease and Inhibitor Mechanisms
  • Venous Thromboembolism Diagnosis and Management

Mukaida's publishing record includes frequent contributions to notable journals such as the International Journal of Molecular Sciences, Metabolism, Cancers, Advances in Experimental Medicine and Biology, and Nature Communications.

  • International Journal of Molecular Sciences
  • Metabolism
  • Cancers
  • Advances in Experimental Medicine and Biology
  • Nature Communications

Frequent collaborators with multiple co-authorships alongside Mukaida include Tomohisa Baba, Yuko Ishida, Toshikazu Kondo, Yumi Kuninaka, and Mizuho Nosaka, indicating ongoing teamwork in research projects related to Mukaida's fields of interest.

Best Publications

  • Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

    J. J. Oppenheim;C. O. C. Zachariae;N. Mukaida;K. Matsushima

  • Essential involvement of interleukin-8 (IL-8) in acute inflammation.

    Akihisa Harada;Nobuaki Sekido;Tohru Akahoshi;Tohru Akahoshi;Takashi Wada

  • Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.

    Taiji Matsusaka;Keiko Fujikawa;Yukihiro Nishio;Naofumi Mukaida

  • Descemet membrane endothelial keratoplasty (DMEK).

    Peirong Lu;Longbiao Li;Naofumi Mukaida;Xueguang Zhang

  • Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis

    Boryana K. Popivanova;Kazuya Kitamura;Yu Wu;Toshikazu Kondo

  • Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.

    N Mukaida;Y Mahe;K Matsushima

  • Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8

    Nobuaki Sekido;Naofumi Mukaida;Akihisa Harada;Isao Nakanishi

  • Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice.

    Zi-Qing Lin;Zi-Qing Lin;Toshikazu Kondo;Yuko Ishida;Tatsunori Takayasu

  • Molecular mechanism of interleukin-8 gene expression

    Naofumi Mukaida;Shu-ichi Okamoto;Yuji Ishikawa;Kouji Matsushima

  • Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-kB-like binding sites of the interleukin 8 gene.

    Kazuo Yasumoto;Shu Ichi Okamoto;Naofumi Mukaida;Seishi Murakami

  • Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases

    Naofumi Mukaida

  • Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions

    Naofumi Mukaida;Akihisa Harada;Kouji Matsushima

  • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.

    N. Mukaida;M. Morita;Y. Ishikawa;N. Rice

  • Retraction: Molecular characterization of Legionella pneumophila -induced interleukin-8 expression in T cells

    Reika Takamatsu;Hiromitsu Teruya;Eriko Takeshima;Chie Ishikawa

  • Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy

    Takashi Wada;Kengo Furuichi;Norihiko Sakai;Yasunori Iwata

  • Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

    Yasushi Sawanobori;Satoshi Ueha;Makoto Kurachi;Takeshi Shimaoka

  • Interleukin-8: an expanding universe beyond neutrophil chemotaxis and activation.

    Naofumi Mukaida

  • Hepatitis C Virus Nonstructural 5A Protein Induces Interleukin-8, Leading to Partial Inhibition of the Interferon-Induced Antiviral Response

    Stephen J. Polyak;Khalid S. A. Khabar;Denise M. Paschal;Heather J. Ezelle

  • IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2.

    Roger S. Smith;Eric R. Fedyk;T. A. Springer;N. Mukaida

  • Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN45.

    Miki Aihara;Daisuke Tsuchimoto;Hisao Takizawa;Atsushi Azuma

Frequent Co-Authors

Kouji Matsushima
Kouji Matsushima Tokyo University of Science
Tadashi Kasahara
Tadashi Kasahara Jichi Medical University
Shuichi Kaneko
Shuichi Kaneko Kanazawa University
Saburo Sone
Saburo Sone University of Tokushima
Hui Wang
Hui Wang University of Ulster
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Kazuhiko Takehara
Kazuhiko Takehara Kanazawa University
Makoto Naito
Makoto Naito Niigata University
Atsushi Hirao
Atsushi Hirao Kanazawa University
Naoki Mori
Naoki Mori University of the Ryukyus

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