World's Best Scientists 2026 revealed!
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
165
Citations
96828
World Ranking
1048
National Ranking
622

Immunology

D-Index
166
Citations
97955
World Ranking
63
National Ranking
44

Medicine

D-Index
166
Citations
98201
World Ranking
610
National Ranking
352

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Steven L. Kunkel is affiliated with the University of Michigan-Ann Arbor in the United States. Their research focuses primarily on medicine and immunology and microbiology, with numerous publications contributing to these fields.

The scientist has contributed extensively to immunology, epidemiology, rehabilitation, molecular biology, and pulmonary and respiratory medicine. Their work encompasses important topics such as immune cells in cancer, wound healing and treatments, immune response and inflammation, immune cell function and interaction, immunotherapy and immune responses, aortic aneurysm repair treatments, and neutrophil, myeloperoxidase, and oxidative mechanisms.

Frequent publication venues for Steven L. Kunkel include:

  • JCI Insight
  • The Journal of Immunology
  • The Journal of Experimental Medicine
  • Cellular and Molecular Immunology
  • Annals of Surgery

Among their recent papers are the following:

  • Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms, 2021, The Journal of Experimental Medicine
  • Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair, 2022, Cellular and Molecular Immunology
  • Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair, 2020, JCI Insight
  • TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF, 2020, JCI Insight
  • Palmitate-TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing, 2020, European Journal of Immunology

Collaboration appears to be an integral part of their scientific output, with frequent co-authors including:

  • Amrita Joshi
  • Katherine Gallagher
  • Frank M. Davis
  • Sonya Wolf
  • Aaron D. denDekker

Steven L. Kunkel's research contributions span 32 publications in the field of medicine and 28 in immunology and microbiology, with 27 focused specifically on immunology as a subfield.

In 2008, they were recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

    Marco Baggiolini;Alfred Walz;Steven L. Kunkel

  • Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

    Alisa E. Koch;Peter J. Polverini;Steven L. Kunkel;Lisa A. Harlow

  • Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

    Laurelee Osborn;Steven Kunkel;Gary J. Nabel

  • Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

    J L Romson;B G Hook;S L Kunkel;G D Abrams

  • Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

    Landin Boring;Jennifa Gosling;Stephen W. Chensue;Steven L. Kunkel

  • The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis

    Robert M. Strieter;Peter J. Polverini;Steven L. Kunkel;Douglas A. Arenberg

  • Abnormalities in Monocyte Recruitment and Cytokine Expression in Monocyte Chemoattractant Protein 1–deficient Mice

    Bao Lu;Barbara J. Rutledge;Long Gu;Joseph Fiorillo

  • Regulation of transendothelial neutrophil migration by endogenous interleukin-8

    Andreas R. Huber;Steven L. Kunkel;Robert F. Todd;Stephen J. Weiss

  • Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

    L M Colletti;D G Remick;G D Burtch;S L Kunkel

  • Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta.

    R. M. Strieter;S. L. Kunkel;H. J. Showell;D. G. Remick

  • CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

    Craig B. Thompson;Tullia Lindsten;Jeffrey A. Ledbetter;Steven L. Kunkel

  • Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups

    S. C. Donnelly;C. Haslett;Robert M. Strieter;Steven L. Kunkel

  • Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.

    A E Koch;S L Kunkel;L A Harlow;B Johnson

  • Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

    T J Standiford;S L Kunkel;M A Basha;S W Chensue

  • Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.

    S L Kunkel;M Spengler;M A May;R Spengler

  • Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

    George E. Griffin;Kwanyee Leung;Thomas M. Folks;Steven Kunkel

  • Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline

    Robert M. Strieter;Daniel G. Remick;Daniel G. Remick;Peter A. Ward;Peter A. Ward;Robert N. Spengler;Robert N. Spengler

  • Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome.

    Richard B. Goodman;Robert M. Strieter;Diane P. Martin;Kenneth P. Steinberg

  • Interleukin-8 (IL-8): The Major Neutrophil Chemotactic Factor in the Lung

    Steven L. Kunkel;Theodore Standiford;Keita Kasahara;Robert M. Strieter

  • Role of tumor necrosis factor-alpha in disease states and inflammation.

    Robert M. Strieter;Steven L. Kunkel;Roger C. Bone

Frequent Co-Authors

Robert M. Strieter
Robert M. Strieter University of Virginia
Nicholas W. Lukacs
Nicholas W. Lukacs University of Michigan–Ann Arbor
Cory M. Hogaboam
Cory M. Hogaboam Cedars-Sinai Medical Center
Theodore J. Standiford
Theodore J. Standiford University of Michigan–Ann Arbor
Stephen W. Chensue
Stephen W. Chensue University of Michigan–Ann Arbor
Marie D. Burdick
Marie D. Burdick University of Virginia
Daniel G. Remick
Daniel G. Remick Boston University
Peter K. Henke
Peter K. Henke University of Michigan–Ann Arbor
Akihiro Matsukawa
Akihiro Matsukawa Okayama University
Joseph P. Lynch
Joseph P. Lynch University of California, Los Angeles

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