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Hidesaburo Hanafusa

Hidesaburo Hanafusa

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
107
Citations
35422
World Ranking
419
National Ranking
30

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 1985 - Member of the National Academy of Sciences

Overview

Hidesaburo Hanafusa was affiliated with the Osaka Bioscience Institute in Japan. Their research contributed to multiple fields within the life sciences, primarily focusing on biochemistry, genetics, and molecular biology, as well as medicine.

The scientist's work spanned several interconnected subfields, including molecular biology, oncology, and genetics. Their research topics frequently addressed protein kinase regulation and GTPase signaling, cytokine signaling pathways and interactions, and virus-based gene therapy research.

Hanafusa published at least one research paper titled "A Role for RAS in V-CRK Transformation" in 2025, which appeared in the venue PubMed. This publication has been cited twenty times, indicating its presence in ongoing research discussions.

  • A Role for RAS in V-CRK Transformation (2025, PubMed)

Collaborative work played a role in their research career, often partnering with coauthors. One known frequent coauthor was Heidi Greulich, with whom Hanafusa worked on at least one publication.

  • Heidi Greulich

Their research was disseminated primarily through the venue PubMed.

  • PubMed (1 publication)

Hanafusa's contributions to science were recognized by membership in the National Academy of Sciences, awarded in 1985.

Best Publications

  • SH2 domains recognize specific phosphopeptide sequences

    Songyang Zhou;Songyang Zhou;Steven E. Shoelson;Manas Chaudhuri;Gerald Gish

  • Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

    Z Songyang;S E Shoelson;J McGlade;P Olivier

  • A novel viral oncogene with structural similarity to phospholipase C.

    Bruce J. Mayer;Michinari Hamaguchi;Hidesaburo Hanafusa

  • CRYSTAL-STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES

    Gabriel Waksman;Dorothea Kominos;Scott C. Robertson;Scott C. Robertson;Nalin Pant

  • TRANCE, a TNF Family Member, Activates Akt/PKB through a Signaling Complex Involving TRAF6 and c-Src

    Brian R Wong;Daniel Besser;Nacksung Kim;Joseph R Arron

  • Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus.

    Tatsuo Takeya;Hidesaburo Hanafusa

  • Evidence for a transcriptional activation function of BRCA1 C-terminal region

    Alvaro N. A. Monteiro;Avery August;Hidesaburo Hanafusa

  • Identification of the Product of Growth Arrest-specific Gene 6 as a Common Ligand for Axl, Sky, and Mer Receptor Tyrosine Kinases

    Kyoko Nagata;Kazumasa Ohashi;Toru Nakano;Hitoshi Arita

  • A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

    F R Cross;E A Garber;D Pellman;H Hanafusa

  • Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins.

    Michiyuki Matsuda;Bruce J. Mayer;Yasuhisa Fukui;Hidesaburo Hanafusa

  • Cell transformation by the viral src oncogene.

    Richard Jove;Hidesaburo Hanafusa

  • BRCA1 regulates p53-dependent gene expression

    Toru Ouchi;Alvaro N. A. Monteiro;Avery August;Stuart A. Aaronson

  • c-Abl kinase regulates the protein binding activity of c-Crk.

    Feller Sm;Knudsen B;Hanafusa H

  • The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region.

    Maria-Magdalena Georgescu;Kathrin H. Kirsch;Tsuyoshi Akagi;Tomoyuki Shishido

  • Cell Transformation by RNA Tumor Viruses

    Hidesaburo Hanafusa

  • Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation

    Tsuyoshi Akagi;Ken Sasai;Hidesaburo Hanafusa

  • Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.

    R. B. Birge;J. E. Fajardo;C. Reichman;S. E. Shoelson

  • Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

    Xiaodong Wu;Beatrice Knudsen;Stephan M Feller;Jie Zheng

  • Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein.

    Alan M. Schultz;Louis E. Henderson;Stephen Oroszlan;Ellen A. Garber

  • The defectiveness of Rous sarcoma virus.

    Hidesaburo Hanafusa;Teruko Hanafusa;Harry Rubin

Frequent Co-Authors

Lu-Hai Wang
Lu-Hai Wang National Health Research Institutes
Bruce J. Mayer
Bruce J. Mayer University of Connecticut
Raymond B. Birge
Raymond B. Birge Rutgers, The State University of New Jersey
Beatrice S. Knudsen
Beatrice S. Knudsen University of Utah
Hisataka Sabe
Hisataka Sabe Hokkaido University
Frederick R. Cross
Frederick R. Cross Rockefeller University
Sally Kornbluth
Sally Kornbluth Duke University
Avery August
Avery August Cornell University
David Pellman
David Pellman Howard Hughes Medical Institute
Hideo Iba
Hideo Iba Chiba University

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