2012 - Fellow of the American Association for the Advancement of Science (AAAS)
2006 - E. Mead Johnson Award, Society for Pediatric Research
Member of the Association of American Physicians
His primary areas of study are Cell biology, Genetics, Aneuploidy, Spindle apparatus and Mitosis. Microtubule is the focus of his Cell biology research. The concepts of his Aneuploidy study are interwoven with issues in Cancer, Polyploid and Human fertilization.
David Pellman works mostly in the field of Spindle apparatus, limiting it down to topics relating to Kinetochore and, in certain cases, Anaphase and Centrosome duplication, as a part of the same area of interest. He combines topics linked to Cancer cell with his work on Mitosis. His work deals with themes such as Carcinogenesis, Hippo signaling pathway, Signal transduction and Cancer research, which intersect with Centrosome.
David Pellman mainly investigates Cell biology, Mitosis, Genetics, Spindle apparatus and Cancer. His studies in Cell biology integrate themes in fields like Cell division, Anaphase, Centrosome and Spindle pole body. The various areas that David Pellman examines in his Mitosis study include Cytokinesis, Chromosome segregation, Chromothripsis, Molecular biology and Mitotic exit.
His research integrates issues of Chromosome breakage, DNA sequencing and DNA replication in his study of Chromothripsis. The Spindle apparatus study combines topics in areas such as Adenomatous polyposis coli and Saccharomyces cerevisiae. His Aneuploidy research incorporates themes from Ploidy and Bioinformatics.
His main research concerns Cell biology, Chromothripsis, Mitosis, Computational biology and Genome. He interconnects Chromatin and DNA in the investigation of issues within Cell biology. Chromothripsis is a subfield of Genome instability that he studies.
His Mitosis research includes themes of Chromosome segregation, Mutation, Cell division, Genetic screen and DNA replication. His Chromosome segregation study integrates concerns from other disciplines, such as Mitotic exit, Centrosome and Nuclear pore. David Pellman has researched Computational biology in several fields, including Chromosome and Whole genome sequencing.
His primary areas of investigation include Mitosis, Chromothripsis, Cell biology, Computational biology and Genome instability. His study in Mitosis is interdisciplinary in nature, drawing from both Aurora B kinase, Aurora Kinase B, Signal transduction, Tumor suppressor gene and DNA replication. His DNA replication research incorporates elements of Gene duplication, Chromosome breakage, Ubiquitin ligase and Cell division.
The study incorporates disciplines such as Chromosome segregation, Cyclin-dependent kinase, Replisome, Chromatin and Centrosome in addition to Cell biology. His Chromosome segregation research is multidisciplinary, incorporating elements of Spindle apparatus, Mitotic exit, Procentriole and Nuclear pore. His research in Computational biology tackles topics such as Genome which are related to areas like Human cancer.
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Absolute quantification of somatic DNA alterations in human cancer
Scott L Carter;Kristian Cibulskis;Elena Helman;Elena Helman;Aaron McKenna.
Nature Biotechnology (2012)
A Mechanism Linking Extra Centrosomes to Chromosomal Instability
Neil J. Ganem;Susana A. Godinho;David Pellman.
DNA breaks and chromosome pulverization from errors in mitosis
Karen Crasta;Neil J. Ganem;Neil J. Ganem;Regina Dagher;Regina Dagher;Alexandra B. Lantermann.
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53 -null cells
Takeshi Fujiwara;Madhavi Bandi;Masayuki Nitta;Elena V. Ivanova.
Causes and consequences of aneuploidy in cancer
David J. Gordon;Benjamin Resio;David Pellman.
Nature Reviews Genetics (2012)
From polyploidy to aneuploidy, genome instability and cancer
Zuzana Storchova;David Pellman.
Nature Reviews Molecular Cell Biology (2004)
Tetraploidy, aneuploidy and cancer.
Neil J Ganem;Zuzana Storchova;David Pellman.
Current Opinion in Genetics & Development (2007)
Chromothripsis from DNA damage in micronuclei
Cheng-Zhong Zhang;Alexander Spektor;Hauke Cornils;Joshua M. Francis.
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
Mijung Kwon;Susana A. Godinho;Namrata S. Chandhok;Neil J. Ganem.
Genes & Development (2008)
Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance
Max A. Tischfield;Hagit N. Baris;Chen Wu;Guenther Rudolph.
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