H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 85 Citations 29,399 156 World Ranking 1381 National Ranking 820

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

2006 - E. Mead Johnson Award, Society for Pediatric Research

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His primary areas of study are Cell biology, Genetics, Aneuploidy, Spindle apparatus and Mitosis. Microtubule is the focus of his Cell biology research. The concepts of his Aneuploidy study are interwoven with issues in Cancer, Polyploid and Human fertilization.

David Pellman works mostly in the field of Spindle apparatus, limiting it down to topics relating to Kinetochore and, in certain cases, Anaphase and Centrosome duplication, as a part of the same area of interest. He combines topics linked to Cancer cell with his work on Mitosis. His work deals with themes such as Carcinogenesis, Hippo signaling pathway, Signal transduction and Cancer research, which intersect with Centrosome.

His most cited work include:

  • Absolute quantification of somatic DNA alterations in human cancer (1159 citations)
  • A Mechanism Linking Extra Centrosomes to Chromosomal Instability (1039 citations)
  • Cytokinesis failure generating tetraploids promotes tumorigenesis in p53 -null cells (797 citations)

What are the main themes of his work throughout his whole career to date?

David Pellman mainly investigates Cell biology, Mitosis, Genetics, Spindle apparatus and Cancer. His studies in Cell biology integrate themes in fields like Cell division, Anaphase, Centrosome and Spindle pole body. The various areas that David Pellman examines in his Mitosis study include Cytokinesis, Chromosome segregation, Chromothripsis, Molecular biology and Mitotic exit.

His research integrates issues of Chromosome breakage, DNA sequencing and DNA replication in his study of Chromothripsis. The Spindle apparatus study combines topics in areas such as Adenomatous polyposis coli and Saccharomyces cerevisiae. His Aneuploidy research incorporates themes from Ploidy and Bioinformatics.

He most often published in these fields:

  • Cell biology (81.36%)
  • Mitosis (41.81%)
  • Genetics (26.55%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (81.36%)
  • Chromothripsis (25.42%)
  • Mitosis (41.81%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Chromothripsis, Mitosis, Computational biology and Genome. He interconnects Chromatin and DNA in the investigation of issues within Cell biology. Chromothripsis is a subfield of Genome instability that he studies.

His Mitosis research includes themes of Chromosome segregation, Mutation, Cell division, Genetic screen and DNA replication. His Chromosome segregation study integrates concerns from other disciplines, such as Mitotic exit, Centrosome and Nuclear pore. David Pellman has researched Computational biology in several fields, including Chromosome and Whole genome sequencing.

Between 2016 and 2021, his most popular works were:

  • Nuclear envelope assembly defects link mitotic errors to chromothripsis (116 citations)
  • Nuclear envelope assembly defects link mitotic errors to chromothripsis (116 citations)
  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing (96 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

His primary areas of investigation include Mitosis, Chromothripsis, Cell biology, Computational biology and Genome instability. His study in Mitosis is interdisciplinary in nature, drawing from both Aurora B kinase, Aurora Kinase B, Signal transduction, Tumor suppressor gene and DNA replication. His DNA replication research incorporates elements of Gene duplication, Chromosome breakage, Ubiquitin ligase and Cell division.

The study incorporates disciplines such as Chromosome segregation, Cyclin-dependent kinase, Replisome, Chromatin and Centrosome in addition to Cell biology. His Chromosome segregation research is multidisciplinary, incorporating elements of Spindle apparatus, Mitotic exit, Procentriole and Nuclear pore. His research in Computational biology tackles topics such as Genome which are related to areas like Human cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Absolute quantification of somatic DNA alterations in human cancer

Scott L Carter;Kristian Cibulskis;Elena Helman;Elena Helman;Aaron McKenna.
Nature Biotechnology (2012)

1354 Citations

A Mechanism Linking Extra Centrosomes to Chromosomal Instability

Neil J. Ganem;Susana A. Godinho;David Pellman.
Nature (2009)

1341 Citations

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53 -null cells

Takeshi Fujiwara;Madhavi Bandi;Masayuki Nitta;Elena V. Ivanova.
Nature (2005)

1074 Citations

DNA breaks and chromosome pulverization from errors in mitosis

Karen Crasta;Neil J. Ganem;Neil J. Ganem;Regina Dagher;Regina Dagher;Alexandra B. Lantermann.
Nature (2012)

969 Citations

From polyploidy to aneuploidy, genome instability and cancer

Zuzana Storchova;David Pellman.
Nature Reviews Molecular Cell Biology (2004)

859 Citations

Causes and consequences of aneuploidy in cancer

David J. Gordon;Benjamin Resio;David Pellman.
Nature Reviews Genetics (2012)

831 Citations

Tetraploidy, aneuploidy and cancer.

Neil J Ganem;Zuzana Storchova;David Pellman.
Current Opinion in Genetics & Development (2007)

740 Citations

Chromothripsis from DNA damage in micronuclei

Cheng-Zhong Zhang;Alexander Spektor;Hauke Cornils;Joshua M. Francis.
Nature (2015)

698 Citations

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

Mijung Kwon;Susana A. Godinho;Namrata S. Chandhok;Neil J. Ganem.
Genes & Development (2008)

590 Citations

An actin nucleation mechanism mediated by Bni1 and Profilin

Isabelle Sagot;Avital A. Rodal;James Moseley;Bruce L. Goode;Bruce L. Goode.
Nature Cell Biology (2002)

582 Citations

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Harvard University

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Harvard University

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