Barbara A. Weir

Overview

Best Publications

• Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

  Roel G. W. Verhaak;Katherine A. Hoadley;Elizabeth Purdom;Victoria Wang

  9586
  Citations

• Comprehensive genomic characterization defines human glioblastoma genes and core pathways

  Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  7310
  Citations

• The landscape of somatic copy-number alteration across human cancers

  Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  4301
  Citations

• Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

  David A. Barbie;Pablo Tamayo;Jesse S. Boehm;So Young Kim

  3341
  Citations

• Somatic mutations affect key pathways in lung adenocarcinoma

  Li Ding;Gad Getz;David A. Wheeler;Elaine R. Mardis

  3191
  Citations

• Next-generation characterization of the Cancer Cell Line Encyclopedia

  Mahmoud Ghandi;Franklin W. Huang;Franklin W. Huang;Franklin W. Huang;Judit Jané-Valbuena;Judit Jané-Valbuena;Gregory V. Kryukov

  2674
  Citations

• Defining a Cancer Dependency Map

  Aviad Tsherniak;Francisca Vazquez;Francisca Vazquez;Phil G. Montgomery;Barbara A. Weir;Barbara A. Weir

  2449
  Citations

• Absolute quantification of somatic DNA alterations in human cancer

  Scott L Carter;Kristian Cibulskis;Elena Helman;Elena Helman;Aaron McKenna

  2050
  Citations

• Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

  Robin M Meyers;Jordan G Bryan;James M McFarland;Barbara A Weir

  1707
  Citations

• Characterizing the cancer genome in lung adenocarcinoma

  Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  1304
  Citations

• Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.

  Kerby Shedden;Jeremy M.G. Taylor;Steven A. Enkemann;Ming Sound Tsao

  1179
  Citations

• SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

  Adam J. Bass;Adam J. Bass;Hideo Watanabe;Hideo Watanabe;Craig H. Mermel;Craig H. Mermel;Soyoung Yu

  1067
  Citations

• β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

  Joseph Rosenbluh;Deepak Nijhawan;Deepak Nijhawan;Deepak Nijhawan;Andrew G. Cox;Andrew G. Cox;Xingnan Li

  816
  Citations

• Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

  Jordi Barretina;Barry S Taylor;Barry S Taylor;Shantanu Banerji;Shantanu Banerji;Alexis H Ramos;Alexis H Ramos

  792
  Citations

• PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

  Martin L. Sos;Mirjam Koker;Barbara A. Weir;Stefanie Heynck

  637
  Citations

• Highly parallel identification of essential genes in cancer cells

  Biao Luo;Hiu Wing Cheung;Aravind Subramanian;Tanaz Sharifnia

  628
  Citations

• Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

  Andrew J Aguirre;Robin M Meyers;Barbara A. Weir;Francisca Vázquez

  619
  Citations

• Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.

  Courtney A. Lovejoy;Wendi Li;Steven Reisenweber;Supawat Thongthip

  617
  Citations

• Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer

  Chang Qi Zhu;Keyue Ding;Dan Strumpf;Barbara A. Weir

  506
  Citations

• MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.

  Gregory V. Kryukov;Gregory V. Kryukov;Frederick H. Wilson;Frederick H. Wilson;Jason R. Ruth;Jason R. Ruth;Joshiawa Paulk;Joshiawa Paulk

  505
  Citations