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Molecular Biology

D-Index
67
Citations
22129
World Ranking
1554
National Ranking
786

Overview

Bruce J. Mayer is affiliated with the University of Connecticut in the United States. Their research spans multiple fields within the broader areas of Biochemistry, Genetics, and Molecular Biology, with significant contributions also in Agricultural and Biological Sciences.

Their research focuses on several subfields including Molecular Biology, Plant Science, Biochemistry, Animal Science and Zoology, and Genetics. Specific topics addressed in their work include RNA Research and Splicing, Lipid Metabolism and Biosynthesis, Plant Molecular Biology Research, RNA Modifications and Cancer, Animal Virus Infections Studies, Virus-based Gene Therapy Research, and Viral Infectious Diseases and Gene Expression in Insects.

Recent publications demonstrate a range of interests primarily in molecular and cellular biology. These include:

  • Measurement of solubility product reveals the interplay of oligomerization and self-association for defining condensate formation, 2024, Molecular Biology of the Cell
  • Measurement of solubility product in a model condensate reveals the interplay of small oligomerization and self-association, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cloning of Avian Sarcoma Virus CT10 and Characterization of its Protein Product, 2025, Digital Commons - RU (Rockefeller University)
  • ConducTORs of a Signaling Symphony: Metabolic and Hormone Responses Converge on TOR and EIN2 in plants., 2022, Faculty Reviews
  • Exploring the solubility product concept for describing the formation of biomolecular condensates by comparing in vitro and in silico systems, 2024, Biophysical Journal

Frequent collaborators include:

  • Aniruddha Chattaraj
  • Zeynep Baltaci
  • Leslie M. Loew
  • Jonathon A. Ditlev
  • Steve Chung

Key publication venues where Bruce J. Mayer has contributed are:

  • Molecular Biology of the Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Digital Commons - RU (Rockefeller University)
  • Faculty Reviews
  • Biophysical Journal

Best Publications

  • Identification of a ten-amino acid proline-rich SH3 binding site

    Ruibao Ren;Bruce J. Mayer;Piera Cicchetti;David Baltimore

  • Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun.

    Sánchez I;Hughes Rt;Mayer Bj;Mayer Bj;Yee K

  • Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

    Zhou Songyang;Zhou Songyang;Kermit L. Carraway;Michael J. Eck;Stephen C. Harrison

  • SH3 domains: complexity in moderation

    B.J. Mayer

  • A novel viral oncogene with structural similarity to phospholipase C.

    Bruce J. Mayer;Michinari Hamaguchi;Hidesaburo Hanafusa

  • CRYSTAL-STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES

    Gabriel Waksman;Dorothea Kominos;Scott C. Robertson;Scott C. Robertson;Nalin Pant

  • Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

    Piera Cicchetti;Bruce J. Mayer;Gerald Thiel;David Baltimore

  • Structure of PAK1 in an Autoinhibited Conformation Reveals a Multistage Activation Switch

    Ming Lei;Wange Lu;Wuyi Meng;Maria-Carla Parrini

  • A putative modular domain present in diverse signaling proteins.

    Bruce J. Mayer;Ruibao Ren;Kirk L. Clark;Kirk L. Clark;David Baltimore

  • The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

    Margareta Nikolic;Margaret M. Chou;Wange Lu;Bruce J. Mayer

  • Nck and Phosphatidylinositol 4,5-Bisphosphate Synergistically Activate Actin Polymerization through the N-WASP-Arp2/3 Pathway

    Rajat Rohatgi;Peter Nollau;Hsin-Yi Henry Ho;Marc W. Kirschner

  • Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins.

    Michiyuki Matsuda;Bruce J. Mayer;Yasuhisa Fukui;Hidesaburo Hanafusa

  • Signalling through SH2 and SH3 domains.

    Bruce J. Mayer;David Baltimore

  • Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases.

    Bruce J. Mayer;Hisamaru Hirai;Ryuichi Sakai

  • An optimized optogenetic clustering tool for probing protein interaction and function

    Amir Taslimi;Justin D. Vrana;Daniel Chen;Sofya Borinskaya

  • Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo.

    B J Mayer;P K Jackson;R A Van Etten;D Baltimore

  • Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck

    Wange Lu;Steve Katz;Ruchika Gupta;Bruce J. Mayer

  • Regulation of PAK Activation and the T Cell Cytoskeleton by the Linker Protein SLP-76

    Juliane Bubeck Wardenburg;Rajita Pappu;Jia-Ying Bu;Bruce Mayer

  • Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins.

    M. Tanaka;Ruchika Gupta;B. J. Mayer

  • NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

    Seng-Lai Tan;Haruhisa Nakao;Yupeng He;Sangeetha Vijaysri

Frequent Co-Authors

Hidesaburo Hanafusa
Hidesaburo Hanafusa Osaka Bioscience Institute
David Baltimore
David Baltimore California Institute of Technology
Leslie M. Loew
Leslie M. Loew University of Connecticut
Michael Overduin
Michael Overduin University of Alberta
David Cowburn
David Cowburn Albert Einstein College of Medicine
Michiyuki Matsuda
Michiyuki Matsuda Kyoto University
Raymond B. Birge
Raymond B. Birge Rutgers, The State University of New Jersey
Michael J. Eck
Michael J. Eck Harvard University
Peter K. Jackson
Peter K. Jackson Stanford University
Søren Brunak
Søren Brunak University of Copenhagen

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