H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 71 Citations 17,315 139 World Ranking 1427 National Ranking 164

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary scientific interests are in Cell biology, Biochemistry, Kinase, Molecular biology and Phosphorylation. In his study, which falls under the umbrella issue of Cell biology, Actin is strongly linked to Cytoskeleton. The Molecular biology study combines topics in areas such as GTPase, Complementary DNA, MAP2K7, breakpoint cluster region and MAP kinase kinase kinase.

His GTPase research incorporates themes from GTPase-activating protein, G protein and Pleckstrin homology domain. His Phosphorylation research is multidisciplinary, incorporating elements of Semaphorin and RHOA. His studies in RHOA integrate themes in fields like Actin cytoskeleton and Myosin.

His most cited work include:

  • A brain serine/threonine protein kinase activated by Cdc42 and Rac1 (1325 citations)
  • The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. (789 citations)
  • PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors (695 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Molecular biology, Biochemistry, Kinase and Internal medicine. His work focuses on many connections between Cell biology and other disciplines, such as Cytoskeleton, that overlap with his field of interest in Actin. His Molecular biology research includes themes of Gene expression, Complementary DNA, Messenger RNA and Signal transduction, Protein kinase C.

Louis Lim has researched Kinase in several fields, including Serine, Phosphorylation and Focal adhesion. His research in GTPase focuses on subjects like GTPase-activating protein, which are connected to Guanine nucleotide exchange factor. His p21-activated kinases research incorporates elements of Rac GTP-Binding Proteins and Membrane ruffling.

He most often published in these fields:

  • Cell biology (63.37%)
  • Molecular biology (44.86%)
  • Biochemistry (36.21%)

What were the highlights of his more recent work (between 2001-2015)?

  • Cell biology (63.37%)
  • Kinase (28.40%)
  • Molecular biology (44.86%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Kinase, Molecular biology, Phosphorylation and RHOA. The study incorporates disciplines such as Neurite and Actin cytoskeleton, Cytoskeleton in addition to Cell biology. His work carried out in the field of Kinase brings together such families of science as Actin, MG132, Myotonic dystrophy and Focal adhesion.

His Focal adhesion research includes elements of PAK1, Guanine nucleotide exchange factor and Mitosis. As part of one scientific family, he deals mainly with the area of Molecular biology, narrowing it down to issues related to the Signal transduction, and often Nuclear export signal and Cell nucleus. His research investigates the connection between RHOA and topics such as Filopodia that intersect with problems in Cytoplasm, Gene isoform and Laminin.

Between 2001 and 2015, his most popular works were:

  • The GIT-Associated Kinase PAK Targets to the Centrosome and Regulates Aurora-A (196 citations)
  • The GIT-Associated Kinase PAK Targets to the Centrosome and Regulates Aurora-A (196 citations)
  • α2-Chimaerin, Cyclin-Dependent Kinase 5/p35, and Its Target Collapsin Response Mediator Protein-2 Are Essential Components in Semaphorin 3A-Induced Growth-Cone Collapse (179 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Louis Lim spends much of his time researching Cell biology, Phosphorylation, Kinase, Molecular biology and Focal adhesion. His Cell biology study incorporates themes from Binding domain and Actin cytoskeleton. In the field of Phosphorylation, his study on PAK1, GSK-3 and Cyclin-dependent kinase 5 overlaps with subjects such as Cyclin-dependent kinase.

His work in Molecular biology addresses issues such as Cytoskeleton, which are connected to fields such as Actin and Protein phosphorylation. In his study, GTPase is inextricably linked to Autophosphorylation, which falls within the broad field of Focal adhesion. His study in Rho-associated protein kinase is interdisciplinary in nature, drawing from both c-Raf, Cyclin-dependent kinase 9, ASK1, Mitogen-activated protein kinase kinase and MAP kinase kinase kinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Edward Manser;Thomas Leung;Harfizah Salihuddin;Zhuo-shen Zhao.
Nature (1994)

2140 Citations

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.

T Leung;X Q Chen;E Manser;L Lim.
Molecular and Cellular Biology (1996)

1234 Citations

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

Edward Manser;Tsui-Han Loo;Cheng-Gee Koh;Zhou-Shen Zhao.
Molecular Cell (1998)

1097 Citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

Thomas Leung;Edward Manser;Lydia Tan;Louis Lim.
Journal of Biological Chemistry (1995)

1004 Citations

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

E Manser;H Y Huang;T H Loo;X Q Chen.
Molecular and Cellular Biology (1997)

848 Citations

Bcr encodes a GTPase-activating protein for p21rac.

Dagmar Diekmann;Suzanne Brill;Michelle D. Garrett;Nicholas Totty.
Nature (1991)

638 Citations

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly.

Zhou-shen Zhao;Edward Manser;Tsui-Han Loo;Louis Lim.
Molecular and Cellular Biology (2000)

520 Citations

A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

Zhou-Shen Zhao;Edward Manser;Xiang-Qun Chen;Claire Chong.
Molecular and Cellular Biology (1998)

482 Citations

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.

Louis Lim;Edward Manser;Thomas Leung;Christine Hall.
FEBS Journal (1996)

446 Citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42.

Edward Manser;Thomas Leung;Harfizah Salihuddin;Lydia Tan.
Nature (1993)

438 Citations

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