Toshimasa Ishizaki

Overview

Best Publications

• Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

  Masayoshi Uehata;Toshimasa Ishizaki;Hiroyuki Satoh;Takashi Ono

  3485
  Citations

• Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

  Midori Maekawa;Toshimasa Ishizaki;Shuken Boku;Naoki Watanabe

  2007
  Citations

• Focal Contacts as Mechanosensors Externally Applied Local Mechanical Force Induces Growth of Focal Contacts by an Mdia1-Dependent and Rock-Independent Mechanism

  Daniel Riveline;Daniel Riveline;Eli Zamir;Nathalie Q. Balaban;Ulrich S. Schwarz

  1801
  Citations

• The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

  Toshimasa Ishizaki;Midori Maekawa;Kazuko Fujisawa;Katsuya Okawa

  1294
  Citations

• Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

  Naoki Watanabe;Takayuki Kato;Akiko Fujita;Toshimasa Ishizaki

  1276
  Citations

• p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.

  Naoki Watanabe;Pascal Madaule;Tim Reid;Toshimasa Ishizaki

  1193
  Citations

• ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

  Osamu Nakagawa;Kazuko Fujisawa;Toshimasa Ishizaki;Yuji Saito

  1087
  Citations

• An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

  Kazuyuki Itoh;Kiyoko Yoshioka;Hitoshi Akedo;Masayoshi Uehata

  927
  Citations

• p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

  Toshimasa Ishizaki;Mamoru Naito;Kazuko Fujisawa;Midori Maekawa

  761
  Citations

• Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion.

  Shuh Narumiya;Masahiro Tanji;Toshimasa Ishizaki

  699
  Citations

• Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

  Kazumasa Ohashi;Kyoko Nagata;Midori Maekawa;Toshimasa Ishizaki

  653
  Citations

• Molecular Dissection of the Rho-associated Protein Kinase (p160ROCK)-regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells

  Masaya Hirose;Toshimasa Ishizaki;Naoki Watanabe;Masayoshi Uehata

  571
  Citations

• Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

  Go Watanabe;Yuji Saito;Pascal Madaule;Toshimasa Ishizaki

  568
  Citations

• Rho effectors and reorganization of actin cytoskeleton.

  Shuh Narumiya;Toshimasa Ishizaki;Naoki Watanabe

  543
  Citations

• Role of citron kinase as a target of the small GTPase Rho in cytokinesis

  Pascal Madaule;Masatoshi Eda;Naoki Watanabe;Kazuko Fujisawa

  490
  Citations

• Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

  Masatoshi Ohgushi;Michiru Matsumura;Mototsugu Eiraku;Kazuhiro Murakami

  484
  Citations

• Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain

  Tim Reid;Tomoyuki Furuyashiki;Toshimasa Ishizaki;Go Watanabe

  481
  Citations

• Use and properties of ROCK-specific inhibitor Y-27632.

  Shuh Narumiya;Toshimasa Ishizaki;Masayoshi Uehata

  459
  Citations

• Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1.

  Toshimasa Ishizaki;Yosuke Morishima;Muneo Okamoto;Tomoyuki Furuyashiki

  447
  Citations

• A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons

  Haruhiko Bito;Tomoyuki Furuyashiki;Hisamitsu Ishihara;Yoshikazu Shibasaki

  391
  Citations