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Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
30494
World Ranking
4943
National Ranking
156

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award

Overview

Lei Wei is a researcher affiliated with Wuhan University in China, specializing in biochemistry, genetics, and molecular biology, with additional contributions to the field of medicine. Their research spans several subfields including molecular biology, cancer research, cell biology, genetics, and oncology.

The main topics addressed in Lei Wei's work encompass:

  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Protein kinase regulation and GTPase signaling
  • Circular RNAs in diseases
  • Extracellular vesicles in disease
  • Cancer-related molecular pathways
  • Hedgehog signaling pathway studies

Lei Wei's recent publications include:

  • "FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells" (2023) published in Bone Research
  • "Rho Kinases in Embryonic Development and Stem Cell Research" (2022) published in Archivum Immunologiae et Therapiae Experimentalis
  • "SCARB1 in extracellular vesicles promotes NPC metastasis by co-regulating M1 and M2 macrophage function" (2023) published in Cell Death Discovery
  • "Jervine inhibits non-small cell lung cancer (NSCLC) progression by suppressing Hedgehog and AKT signaling via triggering autophagy-regulated apoptosis" (2020) published in Biochemical and Biophysical Research Communications
  • "Insight Into Rho Kinase Isoforms in Obesity and Energy Homeostasis" (2022) published in Frontiers in Endocrinology

The frequent coauthors collaborating with Lei Wei include Tao Wang, Zhihong Xie, Fanchao Li, Wentao Dong, and Xuesong Zhu.

The researcher has contributed multiple papers to several publication venues, with notable repeated contributions in Bone Research and Cell Death Discovery. Other venues include Archivum Immunologiae et Therapiae Experimentalis, Biochemical and Biophysical Research Communications, and Frontiers in Endocrinology.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Crystal structure of the tyrosine kinase domain of the human insulin receptor.

    S. R. Hubbard;Lei Wei;L. Ellis;L. Ellis;W. A. Hendrickson;W. A. Hendrickson

  • Cardiomyocyte death in doxorubicin-induced cardiotoxicity

    Yi Wei Zhang;Jianjian Shi;Jianjian Shi;Yuan Jian Li;Lei Wei;Lei Wei

  • The two homologous domains of human angiotensin I-converting enzyme are both catalytically active.

    Lei Wei;Frangois Alhenc-Gelas;Pierre Corvol;Eric Clauser

  • Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides.

    Emmanuel Jaspard;Lei Wei;François Alhenc-Gelas

  • CSCD: a database for cancer-specific circular RNAs

    Siyu Xia;Jing Feng;Ke Chen;Yanbing Ma

  • The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.

    L Wei;E Clauser;F Alhenc-Gelas;P Corvol

  • Rho kinase in the regulation of cell death and survival.

    Jianjian Shi;Lei Wei

  • Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

    Naomi H. Philip;Christopher P. Dillon;Annelise G. Snyder;Patrick Fitzgerald

  • Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis

    Jiang Chang;Min Xie;Viraj R. Shah;Michael D. Schneider

  • Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes

    Lei Wei;F. Alhenc-Gelas;F. Soubrier;A. Michaud

  • CircRNA inhibits DNA damage repair by interacting with host gene

    Xiaolong Xu;Jingwei Zhang;Yihao Tian;Yang Gao

  • Rho kinases play an obligatory role in vertebrate embryonic organogenesis

    Lei Wei;Wilmer Roberts;Lu Wang;Miho Yamada

  • Rho kinase as a therapeutic target in cardiovascular disease

    Michelle Surma;Lei Wei;Jianjian Shi

  • Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis

    Ying Min Zhang;Jacqueline Bo;George E. Taffet;Jiang Chang

  • Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

    Jianjian Shi;Xiangbing Wu;Michelle Surma;Sasidhar Vemula

  • The Age-Related Changes in Cartilage and Osteoarthritis

    YongPing Li;XiaoChun Wei;JingMing Zhou;Lei Wei

  • Novel Insights into the Roles of Rho Kinase in Cancer

    Lei Wei;Michelle Surma;Stephanie Shi;Nathan Lambert-Cheatham

  • RhoA Signaling via Serum Response Factor Plays an Obligatory Role in Myogenic Differentiation

    Lei Wei;Wei Zhou;Jeffrey D. Croissant;Finn Erik Johansen

  • Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells.

    Zhongyuan Wang;Bo Li;Bo Li;Liang Zhou;Shubin Yu

Frequent Co-Authors

Robert J. Schwartz
Robert J. Schwartz University of Houston
Reuben Kapur
Reuben Kapur Indiana University
Jianmin Zhao
Jianmin Zhao Chinese Academy of Sciences
Pierre Corvol
Pierre Corvol Collège de France
Mark L. Entman
Mark L. Entman Baylor College of Medicine
Braden C. Fleming
Braden C. Fleming Brown University
Ge Zhang
Ge Zhang Hong Kong Baptist University
Eric Clauser
Eric Clauser Université Paris Cité
Ling Qin
Ling Qin Chinese University of Hong Kong
Gang Li
Gang Li Chinese University of Hong Kong

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