World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
10302
World Ranking
14522
National Ranking
6103

Overview

Reuben Kapur is affiliated with Indiana University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Within these fields, they have contributed extensively to Molecular Biology, Hematology, Immunology, Genetics, and Cancer Research.

The scientist's work focuses on several main topics, including Acute Myeloid Leukemia Research, Immune Cell Function and Interaction, Epigenetics and DNA Methylation, Hematopoietic Stem Cell Transplantation, Cancer-related Gene Regulation, Immune Cells in Cancer, and Cancer-related Molecular Mechanisms Research.

Among their recent papers are:

  • Obesity-induced inflammation exacerbates clonal hematopoiesis (2023, Journal of Clinical Investigation)
  • An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment (2022, Science Immunology)
  • Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells (2020, Cell Reports)
  • Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid (2020, Journal of Clinical Investigation)
  • Il-1r1 drives leukemogenesis induced by Tet2 loss (2022, Leukemia)

Publications by Reuben Kapur have appeared frequently in the following venues:

  • Blood
  • Leukemia
  • Journal of Clinical Investigation
  • Stem Cell Reviews and Reports
  • Molecular Therapy

The scientist collaborates regularly with several coauthors, including:

  • Baskar Ramdas
  • Santhosh Kumar Pasupuleti
  • Chi Zhang
  • Lakshmi Reddy Palam

Best Publications

  • Stat3 and Stat4 Direct Development of IL-17-Secreting Th Cells

    Anubhav N. Mathur;Hua Chen Chang;Dimitrios G. Zisoulis;Gretta L. Stritesky

  • Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense.

    Andrew W. Roberts;Chaekyun Kim;Ling Zhen;John B. Lowe

  • Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.

    Charlie R. Mantel;Heather A. O'Leary;Brahmananda R. Chitteti;Xinxin Huang

  • Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis

    Zhigang Cai;Jonathan J. Kotzin;Baskar Ramdas;Sisi Chen

  • Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells

    Feng Chun Yang;David A. Ingram;Shi Chen;Cynthia M. Hingtgen

  • Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells.

    Feng Chun Yang;Reuben Kapur;Alastair J. King;Wen Tao

  • Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment

    Jianjian Shi;Xiangbing Wu;Michelle Surma;Sasidhar Vemula

  • Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner

    Lin Wang;Huajia Zhang;Sonia Rodriguez;Liyun Cao

  • T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype

    Anubhav N. Mathur;Hua Chen Chang;Dimitrios G. Zisoulis;Reuben Kapur

  • Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

    Rebecca J. Chan;Melissa B. Leedy;Veerendra Munugalavadla;Cara S. Voorhorst

  • Role of c-Kit and erythropoietin receptor in erythropoiesis

    Veerendra Munugalavadla;Reuben Kapur

  • ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease

    Jilu Zhang;Abdulraouf M. Ramadan;Brad Griesenauer;Wei Li

  • Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

    Qiang Wen;Benjamin Goldenson;Serena J. Silver;Monica Schenone

  • Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation.

    Veerendra Munugalavadla;Louis C. Dore;Bai Lin Tan;Li Hong

  • ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

    Sasidhar Vemula;Jianjian Shi;Philip Hanneman;Lei Wei

  • Therapeutic potential of targeting the oncogenic SHP2 phosphatase.

    Li Fan Zeng;Ruo Yu Zhang;Zhi Hong Yu;Sijiu Li

  • Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

    Fabiola Traina;Fabiola Traina;Valeria Visconte;Anna M. Jankowska;Hideki Makishima

  • Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins

    Yu Li;Jingliang Yan;Pradip De;Hua Chen Chang

  • Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.

    Lingyan Wu;Cong Yan;Magdalena Czader;Oded Foreman

  • Signaling Through the Interaction of Membrane-Restricted Stem Cell Factor and c-kit Receptor Tyrosine Kinase: Genetic Evidence for a Differential Role in Erythropoiesis

    Reuben Kapur;Manus Majumdar;Xiangli Xiao;Monica McAndrews-Hill

Frequent Co-Authors

Mervin C. Yoder
Mervin C. Yoder Indiana University
David A. Ingram
David A. Ingram Indiana University
Zhong Yin Zhang
Zhong Yin Zhang Purdue University West Lafayette
Mark H. Kaplan
Mark H. Kaplan Indiana University
Hal E. Broxmeyer
Hal E. Broxmeyer Indiana University
Helmut Hanenberg
Helmut Hanenberg University of Duisburg-Essen
Lei Wei
Lei Wei Wuhan University
Feng Chun Yang
Feng Chun Yang The University of Texas Health Science Center at San Antonio
Sophie Paczesny
Sophie Paczesny Medical University of South Carolina
Edward F. Srour
Edward F. Srour Indiana University

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