K. Ravi Acharya

Overview

Best Publications

• ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis

  Matthew J Greenway;Peter M Andersen;Carsten Russ;Sean Ennis

  824
  Citations

• Eosinophil granule proteins: form and function.

  K. Ravi Acharya;Steven J. Ackerman

  554
  Citations

• Botulinum and tetanus neurotoxins: structure, function and therapeutic utility

  Kathryn Turton;John A Chaddock;K.Ravi Acharya

  479
  Citations

• The CCN family of proteins: structure-function relationships.

  Kenneth P. Holbourn;K. Ravi Acharya;Bernard Perbal;Bernard Perbal

  469
  Citations

• ACE revisited: A new target for structure-based drug design

  K. Ravi Acharya;Edward D. Sturrock;James F. Riordan;Mario R. W. Ehlers

  422
  Citations

• Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme.

  K.R. Acharya;D.I. Stuart;N.P.C. Walker;M. Lewis

  362
  Citations

• Crystal Structures of Apo- and Holo-bovine α-Lactalbumin at 2.2-Å Resolution Reveal an Effect of Calcium on Inter-lobe Interactions

  E D Chrysina;K Brew;K R Acharya

  329
  Citations

• Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme

  Ramanathan Natesh;Sylva L. U. Schwager;Hazel R. Evans;Edward D. Sturrock

  312
  Citations

• Crystal structure of human α-lactalbumin at 1·7 Å resolution

  K. Ravi Acharya;Jingshan Ren;David I. Stuart;David C. Phillips

  278
  Citations

• Crystal structures of guinea-pig, goat and bovine α-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase

  Ashley C.W. Pike;Keith Brew;K. Ravi Acharya

  272
  Citations

• Angiotensin-Converting Enzyme-2 (ACE2): Comparative Modeling of the Active Site, Specificity Requirements, and Chloride Dependence †

  Jodie L. Guy;Richard M. Jackson;K. Ravi Acharya;Edward D. Sturrock

  239
  Citations

• Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1.

  K R Acharya;E F Passalacqua;E Y Jones;K Harlos

  224
  Citations

• Structural basis for the recognition of carbohydrates by human galectin-7.

  D.D. Leonidas;E.H. Vatzaki;H. Vorum;J.E. Celis

  223
  Citations

• Crystal Structure of the N Domain of Human Somatic Angiotensin I-Converting Enzyme Provides a Structural Basis for Domain-Specific Inhibitor Design.

  Hazel R. Corradi;Sylva L.U. Schwager;Aloysius T. Nchinda;Edward D. Sturrock

  214
  Citations

• Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept

  Andreas Rummel;Timo Eichner;Tanja Weil;Tino Karnath

  207
  Citations

• Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins.

  Demetrios D Leonidas;Boris L Elbert;Zeqi Zhou;Hakon Leffler

  205
  Citations

• Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons

  Vasanta Subramanian;Benedict Crabtree;K. Ravi Acharya

  187
  Citations

• Molecular Recognition and Regulation of Human Angiotensin-I Converting Enzyme (Ace) Activity by Natural Inhibitory Peptides.

  Geoffrey Masuyer;Sylva L. U. Schwager;Edward D. Sturrock;R. Elwyn Isaac

  165
  Citations

• The advantages and limitations of protein crystal structures

  K. Ravi Acharya;Matthew D. Lloyd

  165
  Citations

• Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site.

  Anastassios C Papageorgiou;K.Ravi Acharya;Robert Shapiro;Edward F Passalacqua

  163
  Citations