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D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
10109
World Ranking
18304
National Ranking
7476

Overview

Guo-fu Hu is a researcher affiliated with Tufts Medical Center in the United States. Their work spans the fields of biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, cancer research, immunology, surgery, and physiology.

Hu's research covers several key topics including:

  • Cancer, Hypoxia, and Metabolism
  • MicroRNA in disease regulation
  • Phagocytosis and Immune Regulation
  • Hippo pathway signaling and YAP/TAZ
  • Adipose Tissue and Metabolism
  • Gut microbiota and health
  • Probiotics and Fermented Foods

Their recent publications demonstrate a focus on molecular mechanisms underlying disease processes and immune regulation. Notable papers include:

  • "Angiogenin maintains gut microbe homeostasis by balancing α-Proteobacteria and Lachnospiraceae" (2020) published in Gut
  • "Angiogenin mediates paternal inflammation-induced metabolic disorders in offspring through sperm tsRNAs" (2021) published in Nature Communications
  • "Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages" (2023) published in Biomedicine & Pharmacotherapy
  • "Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis" (2020) published in The EMBO Journal
  • "Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors" (2020) published in Communications Biology

Frequent publication venues for Hu include Nature Communications, Communications Biology, Gut, Biomedicine & Pharmacotherapy, and The EMBO Journal.

Hu collaborates regularly with several coauthors, including Jinghao Sheng, Zhengping Xu, Zihui Yuan, Liang Yuan, and Alexander Hu, reflecting a collaborative research environment.

Best Publications

  • Angiogenin cleaves tRNA and promotes stress-induced translational repression.

    Satoshi Yamasaki;Pavel Ivanov;Guo-fu Hu;Paul Anderson

  • Epithelial-Mesenchymal Transition and Cell Cooperativity in Metastasis

    Takanori Tsuji;Soichiro Ibaragi;Guo Fu Hu

  • Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

    Mohamed M. Emara;Pavel Ivanov;Tyler Hickman;Nemisha Dawra

  • Copper stimulates proliferation of human endothelial cells under culture

    Guo-fu Hu

  • Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis

    Koji Kishimoto;Koji Kishimoto;Shumei Liu;Takanori Tsuji;Karen A. Olson

  • Angiogenin-Cleaved tRNA Halves Interact with Cytochrome c, Protecting Cells from Apoptosis during Osmotic Stress

    Mridusmita Saikia;Raul Jobava;Marc Parisien;Andrea Putnam

  • Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth.

    Takanori Tsuji;Soichiro Ibaragi;Kaori Shima;Miaofen G. Hu

  • Angiogenin Loss-of-Function Mutations in Amyotrophic Lateral Sclerosis

    David Wu;Wenhao Yu;Hiroko Kishikawa;Rebecca D. Folkerth

  • A putative angiogenin receptor in angiogenin-responsive human endothelial cells

    Guo-fu Hu;James F. Riordan;Bert L. Vallee

  • Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation.

    Takanori Tsuji;Yeqing Sun;Yeqing Sun;Koji Kishimoto;Karen A. Olson

  • Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

    Michael A. Van Es;Helenius J. Schelhaas;Paul W J Van Vught;Nicola Ticozzi;Nicola Ticozzi

  • Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

    Mridusmita Saikia;Dawid Krokowski;Bo Jhih Guan;Pavel Ivanov

  • Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities.

    Guo-Fu Hu;James F. Riordan;Bert L. Vallee

  • Emerging role of angiogenin in stress response and cell survival under adverse conditions.

    Shuping Li;Guo-Fu Hu;Guo-Fu Hu

  • SOX9 Is Expressed in Human Fetal Prostate Epithelium and Enhances Prostate Cancer Invasion

    Hongyun Wang;Irwin Leav;Soichiro Ibaragi;Michael Wegner

  • A therapeutic target for prostate cancer based on angiogenin-stimulated angiogenesis and cancer cell proliferation

    Norie Yoshioka;Li Wang;Li Wang;Koji Kishimoto;Takanori Tsuji

  • Actin is a binding protein for angiogenin.

    Guo-Fu Hu;Daniel J. Strydom;James W. Fett;James F. Riordan

  • Neomycin inhibits angiogenin-induced angiogenesis

    Guo-fu Hu

  • Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

    Kevin A. Goncalves;Lev Silberstein;Shuping Li;Nicolas Severe

  • Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.

    Lev Silberstein;Kevin A. Goncalves;Kevin A. Goncalves;Peter V. Kharchenko;Raphael Turcotte

Frequent Co-Authors

James F. Riordan
James F. Riordan Harvard University
Philip W. Hinds
Philip W. Hinds Tufts University
Bert L. Vallee
Bert L. Vallee Harvard University
David T. Scadden
David T. Scadden Harvard University
Paul A. Anderson
Paul A. Anderson University of Wisconsin–Madison
Pavel Ivanov
Pavel Ivanov Brigham and Women's Hospital
Fotini Gounari
Fotini Gounari University of Chicago
Robert H. Brown
Robert H. Brown University of Massachusetts Chan Medical School
Giuseppe D'Alessio
Giuseppe D'Alessio University of Naples Federico II
John Landers
John Landers University of Massachusetts Chan Medical School

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