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Biology and Biochemistry

D-Index
53
Citations
18873
World Ranking
15908
National Ranking
6609

Overview

Philip W. Hinds is affiliated with Tufts University in the United States and has contributed to various research areas primarily in biochemistry, genetics, molecular biology, medicine, and immunology. Their work spans multiple subfields including molecular biology, immunology, oncology, developmental neuroscience, and ophthalmology.

The main topics covered by Hinds' research include:

  • PI3K/AKT/mTOR signaling in cancer
  • Ubiquitin and proteasome pathways
  • Protein degradation and inhibitors
  • Cancer-related molecular pathways
  • Neurogenesis and neuroplasticity mechanisms
  • Epigenetics and DNA methylation
  • Interferon and immune responses

Recent publications by Philip W. Hinds include:

  • "Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47 phox" (2020, Proceedings of the National Academy of Sciences)
  • "A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding" (2022, Proceedings of the National Academy of Sciences)
  • "AKT1 Is Required for a Complete Palbociclib-Induced Senescence Phenotype in BRAF-V600E-Driven Human Melanoma" (2022, Cancers)
  • "AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis" (2023, Cancers)
  • "Hyperlipidemia-induced metabolic changes in regulatory T cells result in altered function" (2021, European Journal of Immunology)

Philip W. Hinds frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Cancers
  • European Journal of Immunology
  • American Journal Of Pathology

Coauthors who have regularly collaborated with Hinds include:

  • Philip N. Tsichlis
  • Abraham Bayer
  • Jodie Pietruska
  • Siobhan K. McRee
  • Jaymes Farrell

Best Publications

  • The p53 proto-oncogene can act as a suppressor of transformation

    Cathy A. Finlay;Philip W. Hinds;Arnold J. Levine

  • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

    C A Finlay;P W Hinds;T H Tan;D Eliyahu

  • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

    Philip W. Hinds;Sibylle Mittnacht;Vjekoslav Dulic;Andrew Arnold

  • Physical interaction of the retinoblastoma protein with human D cyclins

    Steven F. Dowdy;Philip W. Hinds;Kenway Louie;Steven I. Reed

  • Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation.

    P Hinds;C Finlay;A J Levine

  • A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

    Maria Carmen Marin;Christine A. Jost;Louise A. Brooks;Meredith S. Irwin

  • Function of a human cyclin gene as an oncogene.

    Philip W. Hinds;Steven F. Dowdy;Elinor Ng Eaton;Andrew Arnold

  • Cyclins and cdks in development and cancer: a perspective

    Amit Deshpande;Peter Sicinski;Philip W Hinds

  • Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

    P. W. Hinds;C. A. Finlay;R. S. Quartin;S. J. Baker

  • Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.

    Elizabeth Neuman;Mohamed H. Ladha;Nancy Lin;Todd M. Upton

  • The Retinoblastoma Protein Acts as a Transcriptional Coactivator Required for Osteogenic Differentiation

    David M. Thomas;Shannon A. Carty;Denise M. Piscopo;Jong Seo Lee

  • Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis

    Mark W. Landis;Mark W. Landis;Basil S. Pawlyk;Tiansen Li;Piotr Sicinski

  • Tumor suppressor genes

    Philip W. Hinds;Robert A. Weinberg

  • Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

    Cyrille Sage;Mingqian Huang;Kambiz Karimi;Gabriel Gutierrez

  • Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines.

    P W Hinds;C A Finlay;A B Frey;A J Levine

  • PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration.

    Carmen J. Marsit;Shichun Zheng;Kenneth D Aldape;Philip W. Hinds

  • The retinoblastoma protein and the regulation of cell cycling.

    David Cobrinik;Steven F. Dowdy;Philip W. Hinds;Sibylle Mittnacht

  • Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

    David M. Thomas;Sandra A. Johnson;Natalie A. Sims;Melanie K. Trivett

  • P53 is a tumor suppressor gene.

    Arnold J. Levine;Cathy A. Finlay;Philip W. Hinds

  • A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A

    Xin Zhang;Irina Neganova;Stefan Przyborski;Chunbo Yang

Frequent Co-Authors

Charlotte Kuperwasser
Charlotte Kuperwasser Tufts University
David W. P. Thomas
David W. P. Thomas University of Nottingham
Steven F. Dowdy
Steven F. Dowdy University of California, San Diego
Guo-fu Hu
Guo-fu Hu Tufts Medical Center
Philip N. Tsichlis
Philip N. Tsichlis The Ohio State University
Karl Münger
Karl Münger Tufts University
Carmen J. Marsit
Carmen J. Marsit Emory University
John K. Wiencke
John K. Wiencke University of California, San Francisco
Karl T. Kelsey
Karl T. Kelsey Brown University

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