World's Best Scientists 2026 revealed!

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Medicine

D-Index
110
Citations
40401
World Ranking
5610
National Ranking
3016

Overview

John K. Wiencke is affiliated with the University of California, San Francisco in the United States. Their research contributions span multiple areas within medicine and biochemistry, genetics, and molecular biology, with a significant focus on cancer and molecular mechanisms.

The main fields of study addressed in Wiencke's body of work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, the subfields of emphasis are:

  • Molecular Biology
  • Genetics
  • Immunology
  • Oncology
  • Cancer Research

Wiencke has concentrated on several key research topics:

  • Epigenetics and DNA Methylation
  • Glioma Diagnosis and Treatment
  • Ferroptosis and cancer prognosis
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Cancer-related molecular mechanisms research
  • Head and Neck Cancer Studies

The scientist's recent publications include the following:

  • "Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma," 2020, JAMA Oncology
  • "Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling," 2022, Nature Communications
  • "Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma," 2023, Journal of Clinical Oncology
  • "Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers," 2020, Nature Communications
  • "Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer," 2022, Nature Genetics

Frequent co-authors collaborating with Wiencke include:

  • Annette M. Molinaro
  • Karl T. Kelsey
  • Margaret Wrensch
  • Devin C. Koestler
  • Lucas A. Salas

Wiencke's work has appeared regularly in these publication venues:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Clinical Epigenetics
  • Nature Communications

Best Publications

  • DNA methylation arrays as surrogate measures of cell mixture distribution

    Eugene Andres Houseman;William P Accomando;Devin C Koestler;Brock C Christensen

  • Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

    Jeanette E Eckel-Passow;Daniel H Lachance;Annette M. Molinaro;Kyle M. Walsh

  • Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

    Brock C. Christensen;E. Andres Houseman;E. Andres Houseman;Carmen J. Marsit;Shichun Zheng

  • Detectable clonal mosaicism and its relationship to aging and cancer

    Kevin B. Jacobs;Kevin B. Jacobs;Meredith Yeager;Meredith Yeager;Weiyin Zhou;Weiyin Zhou;Sholom Wacholder

  • Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.

    Annette M. Molinaro;Shawn Hervey-Jumper;Ramin A. Morshed;Jacob Young

  • Variants in the CDKN2B and RTEL1 regions are associated with high grade glioma susceptibility

    Margaret Wrensch;Robert B. Jenkins;Jeffrey S. Chang;Ru Fang Yeh

  • Genetic and molecular epidemiology of adult diffuse glioma

    Annette M Molinaro;Jennie W Taylor;John K Wiencke;Margaret R Wrensch

  • The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

    Robert J. A. Bell;H. Tomas Rube;Alex Kreig;Andrew Mancini

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

    Eric J. Duell;John K. Wiencke;Tsun-Jen Cheng;Andrea Varkonyi

  • Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women.

    N L Petrakis;S Barnes;E B King;J Lowenstein

  • Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta

    Heather H. Nelson;John K. Wiencke;David C. Christiani;T. J. Cheng

  • p16INK4a and Histology-specific Methylation of CpG Islands by Exposure to Tobacco Smoke in Non-Small Cell Lung Cancer

    Duk Hwan Kim;Heather H. Nelson;John K. Wiencke;Shichun Zheng

  • Survival and low-grade glioma: the emergence of genetic information.

    Elizabeth B. Claus;Kyle M. Walsh;John K. Wiencke;Annette M. Molinaro

  • Human lymphocytes exposed to low doses of ionizing radiations become refractory to high doses of radiation as well as to chemical mutagens that induce double-strand breaks in DNA.

    Sheldon Wolff;Veena Afzal;J.K. Wiencke;Gregorio Olivieri

  • The landscape of recombination in African Americans

    Anjali G. Hinch;Arti Tandon;Arti Tandon;Nick Patterson;Yunli Song

  • In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia.

    Joseph L. Wiemels;Zhijian Xiao;Patricia A. Buffler;Ana T. Maia

  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

    Beatrice S Melin;Jill S Barnholtz-Sloan;Margaret R Wrensch;Christoffer Johansen

  • Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions

    E. Andres Houseman;E. Andres Houseman;Brock C. Christensen;Ru-Fang Yeh;Carmen J. Marsit

  • Detectable clonal mosaicism and its relationship to aging and cancer

    Kevin B. Jacobs;Meredith Yeager;Weiyin Zhou;Sholom Wacholder

Frequent Co-Authors

Margaret R. Wrensch
Margaret R. Wrensch University of California, San Francisco
Karl T. Kelsey
Karl T. Kelsey Brown University
Joseph L. Wiemels
Joseph L. Wiemels University of Southern California
Paige M. Bracci
Paige M. Bracci University of California, San Francisco
Brock C. Christensen
Brock C. Christensen Dartmouth College
E. Andres Houseman
E. Andres Houseman Oregon State University
Carmen J. Marsit
Carmen J. Marsit Emory University
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine

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